This randomized clinical trial compares the effect of 4 weeks’ administration of inhaled, nebulized inorganic nitrite vs placebo on exercise capacity in patients with heart failure with preserved ejection fraction (HFpEF).
This cohort study investigates associations between blood pressure classifications defined by the 2017 ACC/AHA guidelines in adults younger than 40 years and long-term CVD events including myocardial infarction, heart failure, and stroke.
This population-based cohort study uses a national insurance database data to estimate long-term rates of cardiovascular disease among young Korean adults with elevated blood pressure and stage 1 and 2 hypertension defined by the 2017 ACC/AHA High Blood Pressure Clinical Practice Guideline.
This cohort study uses UK Whitehall II study data to characterize changes in cardiovascular risk factors over 10 years and associations between change in risk and incident cardiovascular events among people without baseline cardiovascular disease.
This Research Letter examines cumulative incidence on autism spectrum disorder in Denmark using nationwide registered diagnosis data from 1980 to 2012 and assesses whether prevalence was stabilized.
This study evaluates primary end points in randomized clinical trials (RCTs) published in 3 major general medical journals to determine how changing the P value threshold for statistical significance from .05 to .005 could affect the interpretation of previously published RCTs.
This Viewpoint compares and contrasts recommendations in the 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) and 2017 American College of Cardiology/American Heart Association (ACC/AHA) blood pressure (BP) guidelines, focusing on definitions of high BP, treatment targets, and BP management for CKD and at older ages.
In this Viewpoint, Eugene Braunwald and coauthor characterize the global prevalence of hypertension as an epidemic and call for collaborative efforts on the part of physicians, other health professionals, and governmental and nongovernmental agencies to develop innovative strategies to manage it, including screening and intervention in nontraditional settings such as barbershops and grocery stores.
This Viewpoint argues for incorporating home blood pressure monitoring measures in primary care pay-for-performance (P4P) quality reporting.
In this narrative medicine essay, two physicians write to their gravely ill 4-year-old daughter promising to try and remain hopeful despite their inability to protect her.
This Clinical Update summarizes the main approaches to out-of-office blood pressure monitoring—home monitoring and ambulatory monitoring and the benefits and challenges of each in the management of hypertension.
A 65-year-old woman with prior RCA NSTEMI treated with PCI presents with home BP fluctuations from <120/80 mm Hg to 200/100 mm Hg and mean 24-hour ambulatory measures of <160/90 mm Hg. How do you interpret the results?
This Medical News article discusses the increased risk of future heart disease and stroke in women who experienced preeclampsia and other pregnancy complications.
This Arts and Medicine essay discusses the relevance of poetry to clinical medicine in an edited transcript of a conversation between physician-poet Rafael Campo and National Book Award–winning poet Mark Doty.
This JAMA Patient Page describes reasons for blood pressure self-monitoring and the steps involved in the procedure.
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