This cluster randomized trial compares associations between commonly used decontamination strategies (chlorhexidine 2% mouthwash, selective oropharyngeal decontamination, and selective digestive tract decontamination) and occurrence of intensive care unit (ICU)–acquired bloodstream infections with multidrug-resistant gram-negative bacteria in ICUs with moderate to high levels of antibiotic resistance.
This randomized clinical trial compares the effects of high-flow nasal vs standard oxygen therapy on 28-day mortality among immunocompromised patients with acute hypoxemic respiratory failure.
This randomized clinical trial compares the ability of lanadelumab—a human monoclonal antibody that selectively inhibits active plasma kallikrein—vs placebo to prevent angioedema among patients with types I and II hereditary angioedema.
This study uses insurance claims database to describe trends in telemedicine use and its associations with physician supply and with state laws madating coverage in a large commercially insured population between 2005 and 2017.
This study examined the rates of patients in the United Kingdom treated with gabapentin and pregabalin for the first time, and the rates of these patients with an off-label indication or a coprescription of opioids or benzodiazepines.
This 2018 Recommendation Statement from the US Preventive Services Task Force concludes that the current evidence is insufficient to assess the balance of benefits and harms of primary care interventions to prevent child maltreatment (I statement).
This systematic review to support the 2018 US Preventive Services Task Force Recommendation Statement on primary care interventions to prevent child maltreatment summarizes published evidence on the benefits and harms of interventions to prevent maltreatment among children with no signs or symptoms of current or past maltreatment.
This Viewpoint argues for reform of the US health care system, starting with the elimination of employment-based insurance.
In this Viewpoint, Hu and Willett survey the accomplishments and future directions of nutritional epidemiology research, arguing for a multidisciplinary approach across the lifecycle using new digital technologies as the best means to address existing uncertainties about optimal diet and nutrition.
This Viewpoint discusses the proposed implementation of “public charge” to immigration policy that would make receipt of public assistance grounds for denying immigrants lawful permanent residence in the United States.
This Viewpoint discusses widespread perceptions of vulnerability and risk that discourage enrollment of pregnant women in clinical trials, and calls for actionable guidelines to overcome those perceptions and eliminate barriers to their participation.
In this narrative medicine essay, an MD-PhD candidate purssuing a graduate degree in the history of medicine uses her study of an early HIV/AIDS archive to reflect on the importance of history in contribution to a proper understanding of contemporary health care and policy and on its vital role in teaching students empathy and emotional intelligence.
A 38-year-old woman with a history of gastric bypass surgery and hysterectomy had acute abdominal pain. Results of routine blood testing were unremarkable; a lung biopsy revealed spindle-cell fascicles with entrapped benign alveolar tissue but no necrosis, atypia, or mitotic activity. What would you do next?
This Medical Letter review summarizes information on the timing, composition, effectiveness, and adverse effects of the 2018-2019 influenza vaccine.
This Medical News article is an interview with the founders of One Tent Health, a nonprofit free HIV screening initiative that serves high-risk neighborhoods in Washington, DC.
This JAMA Patient Page describes the US Preventive Services Task Force’s recommendations on interventions to prevent child maltreatment.
Create a personal account or sign in to: