This randomized trial compares the effects of maternal Down syndrome screening using plasma cell-free DNA (cfDNA) measures vs invasive screening on miscarriage rates among pregnant women at high risk of trisomy 21 based on first-trimester combined screening.
This randomized clinical trial compares the effects of a fixed low-dose triple combination antihypertensive pill vs usual care on high blood pressure control among patients with mild or moderate hypertension treated at urban hospital clinics in Sri Lanka.
This cohort study uses Danish national registry data to investigate associations between traumatic brain injury and suicide in the general Danish population between 1980 and 2014.
This study uses US community cohort data to assess BRCA1 and BRCA2 testing among medically underserved Medicare beneficiaries with breast cancer, ovarian cancer, or both.
This study uses National Inpatient Sample data to characterize trends in transcatheter aortic valve replacement (TAVR) in age groups 55 years and older in the United States from 2012 to 2015.
This Viewpoint discusses how the separation of immigrating children from their parents can result in deleterious long-term physical and psychological effects.
This Viewpoint reviews CDC injury statistics documenting a rise in preventable fatalities in young people related to opioids, motor vehicle crashes, and firearms, and calls for policies aimed at reversing the trend.
This Viewpoint assesses the literature regarding marijuana use during pregnancy and whether it is safe to use as an alternative to opioids for pain management among pregnant women.
This Viewpoint uses recent case law to explore the issue of whether brand-name drug manufacturers can and should be held legally liable for medical harms from generic versions of the same drug produced by other manufacturers with identical labeling.
This Viewpoint reviews the prospects for collapse faced by ACA-created state health insurance Marketplaces if younger and healthier people disenroll and reviews evidence that the Marketplaces are likely still stable enough to provide coverage despite rising premiums.
In this narrative medicine essay, the author flickers in 55-word scenarios through the life of his father who came to the United States as a Vietnamese refugee through his own life working with refugee children as a youth and now as a physician to reflect that the best of who he is resulted from his father seeking a better life.
This commentary discusses a randomized clinical trial published in JAMA Surgery comparing the effects of point-of-care vs video instructions vs in-person training about tourniquet use on correct tourniquet application and skill retention 3 to 9 months after hemorrhage control training.
This JAMA Clinical Update reviews the use of maternal cell-free DNA (cfDNA) analysis to help screen for fetal aneuploidy trisomies 13, 18, 21, and others).
This Clinical Evidence Synopsis summarizes a Cochrane review of randomized trials comparing the effects of the addition of clopidogrel to aspirin therapy vs aspirin therapy alone among patients at high risk for or with established cardiovascular disease.
In this Medical News article, experts discuss the importance of screening for intimate partner violence to detect traumatic brain injuries that may lead to serious cognitive deficits.
This Arts and Medicine essay discusses efforts in US medical centers to develop wall portraiture that honors the full diversity of medical school classes and junior faculty.
This JAMA Patient Page describes the symptoms, diagnosis, and treatment of scabies skin infestation.