This retrospective analysis estimates the additional cost to Medicare of prescribing brand-name combination medications instead of generic constituents by using the Medicare data set of Part D beneficiaries prescribed any of the 1500 medications that accounted for highest total spending in 2015.
This cohort study assesses the association between cardiovascular (CV) health, defined by measures of healthy lifestyle and controlled CV risk factors, and risk of cognitive decline and dementia in community-dwelling people in France aged 65 years or older.
This cross-sectional study examines associations between modifiable cardiovascular risk factors—such as BMI, cholesterol and glucose levels, smoking, and alcohol use—and MRI measures of cerebrovascular structure, function, and white matter integrity in adults aged 18 to 40.
This study uses an US Food and Drug Administration–cleared oximeter to measure the accuracy of the pulse oximetry-based consumer baby monitors Owlet Smart Sock 2 and Baby Vida.
This 2018 Recommendation Statement from the US Preventive Services Task Force makes recommendations regarding use of cervical cytology alone, high-risk HPV testing alone, and both in combination to screen for cervical cancer.
This systematic review to support the 2018 US Preventive Services Task Force Recommendation Statement on screening for cervical cancer summarizes published evidence on the benefits and harms of using high-risk human papillomavirus (hrHPV) testing alone, hrHPV testing with cytology, or cytology alone for cervical cancer screening.
This modeling study uses a microsimulation model of a hypothetical cohort to model the benefits, burden, and harms of cervical cancer screening strategies to inform the 2018 US Preventive Services Task Force Recommendation Statement on screening for cervical cancer in primary care.
This Viewpoint provides a clinical update on Lyme disease, reviewing information on the epidemiology, diagnosis, and treatment of the infection, and discussing the role of Lyme testing in the evaluation of chronic pain and fatigue.
This Viewpoint argues that direct primary care, in which patients contract directly with a primary care physician to pay a recurring out-of-pocket fee for a defined set of benefits, is unlikely to drive improvements in outcomes and reduction in costs because of adverse patient selection and the absence of incentives for physicians to deliver value.
This Viewpoint discusses the importance of understanding how microtimescale influences—fluctuations in mood or motivation on a minute-to-minute or day-to-day basis—affect people’s ability to sustain lifestyle behaviors over a lifetime and envisions development of just-in-time interventions as needed to facilitate daily healthy choices.
This Viewpoint discusses Centers for Medicare & Medicaid Services (CMS) policies requiring physicians to engage patients in shared decision making prior to implantation of an implantable cardioverter-defibrillator, lung cancer screening, and left atrial appendage closure for stroke prevention in atrial fibrillation and argues that better guidance is needed if the requirements are to promote meaningful shared decisions.
In this narrative medicine essay, an opthalmalogist recounts the unexpected results of a cataract removal from a patient who had been blind since she was a teenager following a severe infection that had permanently scarred her corneas.
In this Medical News article, an endocrinologist in Puerto Rico recounts her experiences treating patients during and after last year’s major hurricane.
This JAMA Patient Page describes the US Preventive Services Task Force’s recommendations on screening for cervical cancer.