This randomized clinical trial compares the efficacy and safety of epicutaneous immunotherapy with a peanut patch vs placebo among peanut-allergic children.
This Whitehall II cohort study examines whether midlife diet assessed using the Alternate Healthy Eating Index, a food frequency questionnaire, is associated with subsequent risk for dementia in UK civil servants.
This cohort study uses EHR data from the practices of UK general practitioners to examine the association between an initial prescription for tramadol and all-cause mortality relative to other commonly prescribed NSAIDs (naproxen, diclofenac, celecoxib, etoricoxib) and codeine in patients with osteoarthritis (OA).
This long-term follow-up of a randomized trial reporting no apparent effect of high-dose vs standard-dose prenatal vitamin D supplementation on wheezing in children at the age of 3 years extends the findings an additional 3 years and describes asthma risk at the age of 6 years.
This guideline statement describes development of evidence-based recommendations for detection and management of preoperative anemia, red blood cell (RBC) transfusion, and implementation of patient blood management programs.
As health care costs continue to rise and health system and insurance entities undergo major changes, mistrust and tension has arisen between payers vs physicians and hospitals. This Viewpoint explains the reasons for these tensions, the perspectives of both sides, and proposed and existing solutions for transforming US health care.
This Viewpoint reviews variables influencing the optimal timing of prenatal vaccination, including difference by trimester in vaccine fetal safety, maternal disease susceptibility and immune response, and maternal access to uptake of immunization.
This Viewpoint reports on research that shows reductions in firearm-related homicides in states and counties that have enacted laws restricting firearm access to individuals with a history of violence, restraining orders, or convictions for violent acts including misdemeanor violence and calls for policies with taut oversight systems restricting firearm access to high-risk individuals.
This Viewpoint reviews the Centers for Medicare & Medicaid Services’ (CMS’) Total Cost of Care agreement with Maryland, which incentivizes the state in a demonstration project over 8-years to coordinate care among hospitals, clinics, physicians, and clinicians and ensure that upfront care reduces avoidable costly care later.
In this narrative medicine essay, a palliative care physician shares the story of his 100-year-old grandmother’s last moments surrounded by family and love.
A 31-year-old G2P1 woman who had undergone gastric bypass 4 years prior and is 36 weeks pregnant presents with acute abdominal signs and symptoms that persist after an uncomplicated delivery; a CT scan reveals mesenteric vascular compromise. What is the diagnosis and what would you do next?
This Medical Letter review summarizes doses and formulations of dupilumab (Dupixent), a subcutaneously injected monoclonal antibody add-on maintenance treatment approved for patients aged 12 years or older with moderate to severe asthma with an eosinophilic phenotype or with oral corticosteroid-dependent asthma.
This Medical News story examines the roots of and potential corrective measures for weight bias in health care settings.
This Medical News article discusses a recent systematic review of evidence on health outcomes associated with nonsugar sweeteners.
This JAMA Patient Page describes meningococcal meningitis, its causes, risk factors, and prevention measures.
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