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September 2019 - July 1883

Decade

Year

Issue

April 2, 2019, Vol 321, No. 13, Pages 1229-1320

In This Issue of JAMA

Highlights

Abstract Full Text
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JAMA. 2019;321(13):1229-1231. doi:10.1001/jama.2018.15267
Original Investigation

Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial

Abstract Full Text
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JAMA. 2019;321(13):1261-1274. doi:10.1001/jama.2019.0693

This randomized trial compares the effect of pulmonary vein isolation via catheter ablation vs rate and rhythm control using medical therapy on a composite outcome of death, disabling stroke, serious bleeding, or cardiac arrest in patients with atrial fibrillation (AF).

Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial

Abstract Full Text
free access has active quiz has multimedia
JAMA. 2019;321(13):1275-1285. doi:10.1001/jama.2019.0692

This open-label randomized trial compares the effect of pulmonary vein isolation via catheter ablation vs rate and rhythm control using drug therapy on the quality of life of patients with atrial fibrillation.

Association of Amyloid Positron Emission Tomography With Subsequent Change in Clinical Management Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia

Abstract Full Text
has active quiz
JAMA. 2019;321(13):1286-1294. doi:10.1001/jama.2019.2000

In an attempt to understand if amyloid PET imaging improves the care of patients with MCI or dementia, this cohort study investigates associations between information provided by amyloid PET scan and change in clinical management, defined as a composite of change in drug therapy or counseling about safety and future planning.

Research Letter

Reported Cases of Medical Malpractice in Direct-to-Consumer Telemedicine

Abstract Full Text
JAMA. 2019;321(13):1309-1310. doi:10.1001/jama.2019.0395

In response to physicians’ concerns about exposure to malpractice risk in direct-to-consumer (DTC) telemedicine, this study reviews the LexisNexis legal case database for reported cases of medical malpractice related to DTC telemedicine services or their health care professionals.

Viewpoint

Evolving Issues in Oncology

The Surprisingly Positive Association Between Obesity and Cancer Immunotherapy Efficacy

Abstract Full Text
has audio
JAMA. 2019;321(13):1247-1248. doi:10.1001/jama.2019.0463

This Viewpoint reviews early evidence of improved outcomes among patients with cancer and higher BMIs treated with tumor checkpoint inhibitors, and the scientific challenges of distinguishing the mechanism of favorable vs adverse effects of obesity on cancer epidemiology and responses to treatment.

Reexamining Recommendations for Treatment of Hypercholesterolemia in Older Adults

Abstract Full Text
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JAMA. 2019;321(13):1249-1250. doi:10.1001/jama.2019.1676

This Viewpoint discusses the 2018 ACC/AHA cholesterol management guideline recommendation to consider statin treatment in adults aged >75 years with LDL levels 70-189 mg/dL, arguing that trial evidence does not support it, the drugs may be harmful and difficult to discontinue in older populations, and that the decision to start medication should be shared with the patient and incorporate assessments of risk, benefit, and patient preferences and values.

Current and Future Challenges for Children Across the World

Abstract Full Text
JAMA. 2019;321(13):1251-1252. doi:10.1001/jama.2019.1840

This Viewpoint argues that children have been left behind in UN and other global health efforts, calls for a focus on health measures beyond survival to define success, and outlines requirements to achieve real improvements in child health, including access to preventive care, a focus on education and nutrition, and introduction of information systems to monitor the population effects of health services.

A Piece of My Mind

What About Recovery

Abstract Full Text
JAMA. 2019;321(13):1253-1254. doi:10.1001/jama.2019.2134

In this narrative medicine essay, an internist uses her brother’s slow death after an unnecessary hospitalization characterized by overuse of invasive procedures and no coordination of care to emphasize the importance of a healing and rehabilitation mindset in inpatient care.

Editorial

Catheter Ablation for Atrial Fibrillation: Lessons Learned From CABANA

Abstract Full Text
has multimedia
JAMA. 2019;321(13):1255-1257. doi:10.1001/jama.2018.17478

Amyloid PET and Changes in Clinical Management for Patients With Cognitive Impairment

Abstract Full Text
JAMA. 2019;321(13):1258-1260. doi:10.1001/jama.2019.1998
Review

Cerebral Intraparenchymal Hemorrhage: A Review

Abstract Full Text
has active quiz
JAMA. 2019;321(13):1295-1303. doi:10.1001/jama.2019.2413

This narrative review summarizes the pathophysiology, presentation, and management of patients with intraparenchymal hemorrhagic stroke, and approaches to poststroke rehabilitation, risk factor management, and anticoagulation.

JAMA Guide to Statistics and Methods

Marginal Effects—Quantifying the Effect of Changes in Risk Factors in Logistic Regression Models

Abstract Full Text
JAMA. 2019;321(13):1304-1305. doi:10.1001/jama.2019.1954

This JAMA Guide to Statistics and Methods discusses the marginal effects approach to express the strength of the association between a risk factor and a binary outcome from a logistic regression.

From The Medical Letter on Drugs and Therapeutics

An Epinephrine Prefilled Syringe (Symjepi) for Anaphylaxis

Abstract Full Text
JAMA. 2019;321(13):1306-1307. doi:10.1001/jama.2019.0898

This Medical Letter review summarizes the use of Symjepi, a single-dose, prefilled epinephrine syringe for manual infection during emergency treatment of anaphylaxis.

Medical News & Perspectives

Why Do Hundreds of US Women Die Annually in Childbirth?

Abstract Full Text
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JAMA. 2019;321(13):1239-1241. doi:10.1001/jama.2019.0714

This Medical News article discusses ongoing efforts to better track and prevent maternal mortality in the US.

Quick Uptakes: After Rotavirus Vaccine, Australia’s Type 1 Diabetes Incidence Declines

Abstract Full Text
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JAMA. 2019;321(13):1241-1242. doi:10.1001/jama.2019.0766

This Medical News article discusses a recently discovered association between rotavirus vaccination and a decline in new type 1 diabetes cases among young Australian children.

News From the Food and Drug Administration

Higher Dose of Tofacitinib for Rheumatoid Arthritis Poses Risks

Abstract Full Text
JAMA. 2019;321(13):1245. doi:10.1001/jama.2019.2986

Collaboration Aims to Expedite Diagnostic Testing in Emergencies

Abstract Full Text
JAMA. 2019;321(13):1245. doi:10.1001/jama.2019.2988

Another Warning for Febuxostat

Abstract Full Text
JAMA. 2019;321(13):1245. doi:10.1001/jama.2019.3043
The JAMA Forum

The 6 Functions of Health Insurance

Abstract Full Text
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JAMA. 2019;321(13):1242-1243. doi:10.1001/jama.2019.2320
Bench to Bedside

Studies Further Support Transmissibility of Alzheimer Disease–Associated Proteins

Abstract Full Text
JAMA. 2019;321(13):1243-1244. doi:10.1001/jama.2019.2650
The Arts and Medicine

Artist, Rediscovered: Images and Ethics of Early Prostate Cancer Screening

Abstract Full Text
JAMA. 2019;321(13):1236-1238. doi:10.1001/jama.2019.1600

This Arts and Medicine essay reviews a museum exhibit devoted to the Bowery series, an early attempt at prostate cancer screening that recruited vulnerable men to undergo surgical prostate biopsies, and the career of Tod Dee Craig, the artist who illustrated the surgical procedures and findings.

Poetry and Medicine

Et mu

Abstract Full Text
JAMA. 2019;321(13):1315. doi:10.1001/jama.2018.18920
JAMA Revisited

Current Comment

Abstract Full Text
JAMA. 2019;321(13):1316. doi:10.1001/jama.2018.15275
JAMA Patient Page

Upper Blepharoplasty

Abstract Full Text
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JAMA. 2019;321(13):1320. doi:10.1001/jama.2019.1957

This JAMA Patient Page describes the upper blepharoplasty procedure.

Comment & Response

Hypertension in Young Adults and Subsequent Cardiovascular Disease

Abstract Full Text
JAMA. 2019;321(13):1310. doi:10.1001/jama.2019.0061

Hypertension in Young Adults and Subsequent Cardiovascular Disease—Reply

Abstract Full Text
JAMA. 2019;321(13):1310-1311. doi:10.1001/jama.2019.0065

Tidal Volume Ventilation Strategy in ICU Patients Without ARDS

Abstract Full Text
JAMA. 2019;321(13):1311-1312. doi:10.1001/jama.2019.0298

Tidal Volume Ventilation Strategy in ICU Patients Without ARDS—Reply

Abstract Full Text
JAMA. 2019;321(13):1312-1313. doi:10.1001/jama.2019.0306

Pharmacist-Led Education to Discontinue Inappropriate Prescribing

Abstract Full Text
JAMA. 2019;321(13):1313-1314. doi:10.1001/jama.2019.0302

Pharmacist-Led Education to Discontinue Inappropriate Prescribing—Reply

Abstract Full Text
JAMA. 2019;321(13):1314. doi:10.1001/jama.2019.0311
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2019;321(13):1233-1234. doi:10.1001/jama.2018.15268
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