This randomized trial compares the effect of pulmonary vein isolation via catheter ablation vs rate and rhythm control using medical therapy on a composite outcome of death, disabling stroke, serious bleeding, or cardiac arrest in patients with atrial fibrillation (AF).
This open-label randomized trial compares the effect of pulmonary vein isolation via catheter ablation vs rate and rhythm control using drug therapy on the quality of life of patients with atrial fibrillation.
In an attempt to understand if amyloid PET imaging improves the care of patients with MCI or dementia, this cohort study investigates associations between information provided by amyloid PET scan and change in clinical management, defined as a composite of change in drug therapy or counseling about safety and future planning.
In response to physicians’ concerns about exposure to malpractice risk in direct-to-consumer (DTC) telemedicine, this study reviews the LexisNexis legal case database for reported cases of medical malpractice related to DTC telemedicine services or their health care professionals.
This Viewpoint reviews early evidence of improved outcomes among patients with cancer and higher BMIs treated with tumor checkpoint inhibitors, and the scientific challenges of distinguishing the mechanism of favorable vs adverse effects of obesity on cancer epidemiology and responses to treatment.
This Viewpoint discusses the 2018 ACC/AHA cholesterol management guideline recommendation to consider statin treatment in adults aged >75 years with LDL levels 70-189 mg/dL, arguing that trial evidence does not support it, the drugs may be harmful and difficult to discontinue in older populations, and that the decision to start medication should be shared with the patient and incorporate assessments of risk, benefit, and patient preferences and values.
This Viewpoint argues that children have been left behind in UN and other global health efforts, calls for a focus on health measures beyond survival to define success, and outlines requirements to achieve real improvements in child health, including access to preventive care, a focus on education and nutrition, and introduction of information systems to monitor the population effects of health services.
In this narrative medicine essay, an internist uses her brother’s slow death after an unnecessary hospitalization characterized by overuse of invasive procedures and no coordination of care to emphasize the importance of a healing and rehabilitation mindset in inpatient care.
This narrative review summarizes the pathophysiology, presentation, and management of patients with intraparenchymal hemorrhagic stroke, and approaches to poststroke rehabilitation, risk factor management, and anticoagulation.
This JAMA Guide to Statistics and Methods discusses the marginal effects approach to express the strength of the association between a risk factor and a binary outcome from a logistic regression.
This Medical Letter review summarizes the use of Symjepi, a single-dose, prefilled epinephrine syringe for manual infection during emergency treatment of anaphylaxis.
This Medical News article discusses ongoing efforts to better track and prevent maternal mortality in the US.
This Medical News article discusses a recently discovered association between rotavirus vaccination and a decline in new type 1 diabetes cases among young Australian children.
This Arts and Medicine essay reviews a museum exhibit devoted to the Bowery series, an early attempt at prostate cancer screening that recruited vulnerable men to undergo surgical prostate biopsies, and the career of Tod Dee Craig, the artist who illustrated the surgical procedures and findings.
This JAMA Patient Page describes the upper blepharoplasty procedure.
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