This randomized clinical trial compares the effects of 3-, 7-, and 14-mg/d of oral semaglutide vs sitagliptin on glycated hemoglobin in patients with type 2 diabetes uncontrolled with metformin alone or with sulfonylurea.
This phase 3 randomized trial compares the effect of doxepin mouthwash or diphenhydramine-lidocaine-antacid mouthwash on oral mucositis–related pain among patients who underwent definitive head and neck radiotherapy.
This cluster randomized clinical trial evaluates the effects of a workplace wellness program comprising nutrition, physical activity, and stress reduction modules on self-reported lifestyle outcomes (exercise, diet, smoking, alcohol use), clinical measures (eg, cholesterol, blood pressure, body mass index [BMI]), spending and utilization measures, and employment outcomes (absenteeism job tenure, job performance).
This study characterizes the proportion of apps available in 2018 for self-management of type 2 diabetes that included goal-setting features, reminders to measure blood glucose, hypoglycemia and hyperglycemia alerts, and action prompts.
This 2019 Recommendation Statement from the US Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for elevated blood lead levels in asymptomatic children (I statement) and asymptomatic pregnant persons (I statement).
This systematic review to support the 2019 US Preventive Services Task Force Recommendation Statement on screening for elevated blood lead levels in childhood and pregnancy summarizes published evidence on the benefits and harms of screening and intervention for elevated blood lead levels in pregnant women and children 5 years and younger in the primary care setting.
Given considerable empirical support for using financial incentives to motivate desired behaviors, this Viewpoint reviews behavioral economics principles and methodological reasons that might explain the absence of an effect of financial rewards on medication adherence and health outcomes in several recent randomized trials.
This Viewpoint describes the peer review processes of the Patient-Centered Outcomes Research Institute, the yield since 2010 of publicly posted final reports of funded comparative effectiveness studies, and speculates that the benefits of the legislatively mandated process may someday outweigh its many current procedural challenges.
In this narrative medicine essay an otolaryngologist remembers a patient who identifies her physicians as characters in the television show Grey’s Anatomy, a playful reference that makes her advanced cancer hospitalizations bearable and disarms her physicians through diversion and humor.
This JAMA Clinical Guidelines Synopsis summarizes the 2017 focused update of the American College of Cardiology/American Heart Association (AHA/ACC) guideline on management of patients with severe aortic stenosis focusing on surgical vs transcatheter valve replacement (TAVR).
This Medical News article is an interview with the first pediatrician and second woman physician to serve in Congress.
This Medical News feature summarizes a recent study exploring the link between childhood lead exposure and mental health and personality in adulthood.
This JAMA Patient Page describes the US Preventive Services Task Force’s recent recommendations on screening for high blood lead levels in children and pregnant women.
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