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September 2019 - July 1883

Decade

Year

Issue

April 16, 2019, Vol 321, No. 15, Pages 1429-1542

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2019;321(15):1429-1431. doi:10.1001/jama.2018.15289
Original Investigation

Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2019;321(15):1466-1480. doi:10.1001/jama.2019.2942

This randomized clinical trial compares the effects of 3-, 7-, and 14-mg/d of oral semaglutide vs sitagliptin on glycated hemoglobin in patients with type 2 diabetes uncontrolled with metformin alone or with sulfonylurea.

Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial

Abstract Full Text
JAMA. 2019;321(15):1481-1490. doi:10.1001/jama.2019.3504

This phase 3 randomized trial compares the effect of doxepin mouthwash or diphenhydramine-lidocaine-antacid mouthwash on oral mucositis–related pain among patients who underwent definitive head and neck radiotherapy.

Effect of a Workplace Wellness Program on Employee Health and Economic Outcomes: A Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA. 2019;321(15):1491-1501. doi:10.1001/jama.2019.3307

This cluster randomized clinical trial evaluates the effects of a workplace wellness program comprising nutrition, physical activity, and stress reduction modules on self-reported lifestyle outcomes (exercise, diet, smoking, alcohol use), clinical measures (eg, cholesterol, blood pressure, body mass index [BMI]), spending and utilization measures, and employment outcomes (absenteeism job tenure, job performance).

Research Letter

Decision Support and Alerts of Apps for Self-management of Blood Glucose for Type 2 Diabetes

Abstract Full Text
JAMA. 2019;321(15):1530-1532. doi:10.1001/jama.2019.1644

This study characterizes the proportion of apps available in 2018 for self-management of type 2 diabetes that included goal-setting features, reminders to measure blood glucose, hypoglycemia and hyperglycemia alerts, and action prompts.

US Preventive Services Task Force

Recommendation Statement

Screening for Elevated Blood Lead Levels in Children and Pregnant Women: US Preventive Services Task Force Recommendation Statement

Abstract Full Text
free access has active quiz has audio
JAMA. 2019;321(15):1502-1509. doi:10.1001/jama.2019.3326

This 2019 Recommendation Statement from the US Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for elevated blood lead levels in asymptomatic children (I statement) and asymptomatic pregnant persons (I statement).

Evidence Report

Screening for Elevated Blood Lead Levels in Childhood and Pregnancy: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Abstract Full Text
free access
JAMA. 2019;321(15):1510-1526. doi:10.1001/jama.2019.1004

This systematic review to support the 2019 US Preventive Services Task Force Recommendation Statement on screening for elevated blood lead levels in childhood and pregnancy summarizes published evidence on the benefits and harms of screening and intervention for elevated blood lead levels in pregnant women and children 5 years and younger in the primary care setting.

Viewpoint

The Uncertain Effect of Financial Incentives to Improve Health Behaviors

Abstract Full Text
has audio
JAMA. 2019;321(15):1451-1452. doi:10.1001/jama.2019.2560

Given considerable empirical support for using financial incentives to motivate desired behaviors, this Viewpoint reviews behavioral economics principles and methodological reasons that might explain the absence of an effect of financial rewards on medication adherence and health outcomes in several recent randomized trials.

A Model for Public Access to Trustworthy and Comprehensive Reporting of Research

Abstract Full Text
JAMA. 2019;321(15):1453-1454. doi:10.1001/jama.2019.2807

This Viewpoint describes the peer review processes of the Patient-Centered Outcomes Research Institute, the yield since 2010 of publicly posted final reports of funded comparative effectiveness studies, and speculates that the benefits of the legislatively mandated process may someday outweigh its many current procedural challenges.

A Piece of My Mind

Casting

Abstract Full Text
JAMA. 2019;321(15):1455-1456. doi:10.1001/jama.2019.3954

In this narrative medicine essay an otolaryngologist remembers a patient who identifies her physicians as characters in the television show Grey’s Anatomy, a playful reference that makes her advanced cancer hospitalizations bearable and disarms her physicians through diversion and humor.

Editorial

The Future of the GLP-1 Receptor Agonists

Abstract Full Text
JAMA. 2019;321(15):1457-1458. doi:10.1001/jama.2019.2941

The Search for an Effective Therapy and Pain Relief for Oral Mucositis

Abstract Full Text
JAMA. 2019;321(15):1459-1461. doi:10.1001/jama.2019.3269

Employer Wellness Programs—A Work in Progress

Abstract Full Text
JAMA. 2019;321(15):1462-1463. doi:10.1001/jama.2019.3376

Screening for Elevated Blood Lead Levels in Children and Pregnant Women

Abstract Full Text
JAMA. 2019;321(15):1464-1465. doi:10.1001/jama.2019.2594
JAMA Clinical Guidelines Synopsis

Management of Patients With Severe Aortic Stenosis With Transcatheter Valve Replacement

Abstract Full Text
JAMA. 2019;321(15):1527-1528. doi:10.1001/jama.2019.1336

This JAMA Clinical Guidelines Synopsis summarizes the 2017 focused update of the American College of Cardiology/American Heart Association (AHA/ACC) guideline on management of patients with severe aortic stenosis focusing on surgical vs transcatheter valve replacement (TAVR).

Medical News & Perspectives

Dr Schrier Goes to Congress as Second Woman Physician

Abstract Full Text
free access has audio
JAMA. 2019;321(15):1443-1445. doi:10.1001/jama.2019.1704

This Medical News article is an interview with the first pediatrician and second woman physician to serve in Congress.

Quick Uptakes

Childhood Lead Exposure May Affect Personality, Mental Health in Adulthood

Abstract Full Text
free access has multimedia
JAMA. 2019;321(15):1445-1446. doi:10.1001/jama.2019.1116

This Medical News feature summarizes a recent study exploring the link between childhood lead exposure and mental health and personality in adulthood.

News From the Food and Drug Administration

Robotically Assisted Surgical Devices Raise Caution

Abstract Full Text
JAMA. 2019;321(15):1449. doi:10.1001/jama.2019.3834

New Therapy for Treatment-Resistant Depression

Abstract Full Text
JAMA. 2019;321(15):1449. doi:10.1001/jama.2019.3596

Agreement to Regulate Cell-Based Meat Products

Abstract Full Text
JAMA. 2019;321(15):1449. doi:10.1001/jama.2019.3831
The JAMA Forum

Making Amends for the Opioid Epidemic

Abstract Full Text
free access
JAMA. 2019;321(15):1446-1447. doi:10.1001/jama.2019.3505
Global Health

Monster 2015-2016 El Niño Event Triggered Infectious Diseases

Abstract Full Text
JAMA. 2019;321(15):1448. doi:10.1001/jama.2019.3155

Cancer Goes Undiagnosed in Almost Half the World’s Children

Abstract Full Text
JAMA. 2019;321(15):1448. doi:10.1001/jama.2019.3827

Antimicrobial Resistance on the Rise in Zoonotic Bacteria in Europe

Abstract Full Text
JAMA. 2019;321(15):1448. doi:10.1001/jama.2019.3829
Poetry and Medicine

The MRI

Abstract Full Text
JAMA. 2019;321(15):1536. doi:10.1001/jama.2018.22127
JAMA Revisited

The Foxhall Fossil Human Jawbone

Abstract Full Text
JAMA. 2019;321(15):1537. doi:10.1001/jama.2018.15297
JAMA Patient Page

Screening for High Blood Lead Levels in Children and Pregnant Women

Abstract Full Text
free access
JAMA. 2019;321(15):1542. doi:10.1001/jama.2019.2944

This JAMA Patient Page describes the US Preventive Services Task Force’s recent recommendations on screening for high blood lead levels in children and pregnant women.

Comment & Response

Lowering the P Value Threshold

Abstract Full Text
JAMA. 2019;321(15):1532-1533. doi:10.1001/jama.2019.0566

Lowering the P Value Threshold—Reply

Abstract Full Text
JAMA. 2019;321(15):1533. doi:10.1001/jama.2019.0574

Evaluation for Fibrosis After Cure of Hepatitis C

Abstract Full Text
JAMA. 2019;321(15):1534. doi:10.1001/jama.2019.0865

Evaluation for Fibrosis After Cure of Hepatitis C

Abstract Full Text
JAMA. 2019;321(15):1534-1535. doi:10.1001/jama.2019.0869

Evaluation for Fibrosis After Cure of Hepatitis C—Reply

Abstract Full Text
JAMA. 2019;321(15):1535. doi:10.1001/jama.2019.0873
Correction

Error in JAMA Forum Article on Pelvic Examination Under Anesthesia

Abstract Full Text
free access
JAMA. 2019;321(15):1535. doi:10.1001/jama.2019.3638

Incorrect Numeric Value

Abstract Full Text
free access
JAMA. 2019;321(15):1535. doi:10.1001/jama.2019.4034
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2019;321(15):1433-1434. doi:10.1001/jama.2018.15290
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