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July 2019 - July 1883

Decade

Year

Issue

May 28, 2019, Vol 321, No. 20, Pages 1953-2040

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2019;321(20):1953-1955. doi:10.1001/jama.2018.15344
Original Investigation

Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA. 2019;321(20):1983-1992. doi:10.1001/jama.2019.5359

This randomized noninferiority trial compares the effect of laparoscopic distal gastrectomy with open distal gastrectomy for locally advanced gastric cancer.

Caring for the Critically Ill Patient

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial

Abstract Full Text
JAMA. 2019;321(20):1993-2002. doi:10.1001/jama.2019.5358

This randomized trial compares the effect of recombinant human soluble thrombomodulin vs placebo in patients with sepsis-associated coagulopathy on 28-day all-cause mortality.

Caring for the Critically Ill Patient

Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

Abstract Full Text
has active quiz
JAMA. 2019;321(20):2003-2017. doi:10.1001/jama.2019.5791

In this study, Sepsis-3 investigators use electronic health record and trial data from patients with sepsis within 6 hours of hospital presentation to define clinical phenotypes that correlate with host-response patterns, sepsis biomarkers, mortality, and treatment effects.

Research Letter

Specialty Drug Pricing and Out-of-Pocket Spending on Orally Administered Anticancer Drugs in Medicare Part D, 2010 to 2019

Abstract Full Text
JAMA. 2019;321(20):2025-2028. doi:10.1001/jama.2019.4492

This study describes point-of-sale prices for orally administered anticancer drugs offered through Medicare Part D and out-of-pocket changes in spending as a result of decreasing coinsurance and price changes between 2010 and 2019.

Penalties and Rewards for Safety Net vs Non–Safety Net Hospitals in the First 2 Years of the Comprehensive Care for Joint Replacement Model

Abstract Full Text
JAMA. 2019;321(20):2027-2030. doi:10.1001/jama.2019.5118

This study compared monetary penalties and rewards among safety net vs non–safety net hospitals under Medicare’s Comprehensive Care for Joint Replacement (CJR) model, a bundled payment plan for hip and knee replacements intended to incentivize health care quality and savings, in 2016 and 2017.

Viewpoint

Treatment of Patients With Psychogenic Nonepileptic Attacks

Abstract Full Text
has audio
JAMA. 2019;321(20):1967-1968. doi:10.1001/jama.2019.3520

This Viewpoint describes the neurological disorder known as psychogenic nonepileptic attacks (PNEA)—including the symptoms, appropriate diagnostic testing, and treatment with cognitive behavioral therapy—and how it can be distinguished from epilepsy to avoid treating patients with PNEA with potentially harmful epileptic medications or surgery.

Safe Vaccinations for a Healthy Nation: Increasing US Vaccine Coverage Through Law, Science, and Communication

Abstract Full Text
JAMA. 2019;321(20):1969-1970. doi:10.1001/jama.2019.4270

This Viewpoint discusses public distrust of vaccinations fueled by false information on vaccine safety spread through social media, and discusses the ways in which physicians, public health authorities, states, and social media platforms can help curb the spread of misinformation and instead provide information on the safety and importance of vaccines.

Is It Time for Safeguards in the Adoption of Robotic Surgery?

Abstract Full Text
JAMA. 2019;321(20):1971-1972. doi:10.1001/jama.2019.3736

This Viewpoint discusses the increasing use of robotic-assisted surgery and the issues, including potential harm, surgeon credentialing, and transparency in informed patient consent, that should be considered by payers, health care organizations, and surgeons to ensure that safeguards remain in place until stronger evidence for or against the use of this technology is available.

Health Concerns in Urban Slums: A Glimpse of Things to Come?

Abstract Full Text
JAMA. 2019;321(20):1973-1974. doi:10.1001/jama.2019.3774

In this Viewpoint, authors from the International Center for Diarrheal Disease Research in Bangladesh discuss rapid urbanization in low- and middle-income countries and the associated challenges of meeting the basic health care needs of growing urban slum populations.

Serving Individuals and Populations Within Integrated Health Systems: A Bridge Too Far?

Abstract Full Text
JAMA. 2019;321(20):1975-1976. doi:10.1001/jama.2019.2929

This Viewpoint discusses the realities that keep integrated health systems (IHSs) from providing a full range of patient care services from primary through quaternary care, and outlines strategic considerations important for IHS stakeholders to account for if they are to effectively serve their patient communities in a shifting technological and regulatory environment.

A Piece of My Mind

Metronome

Abstract Full Text
JAMA. 2019;321(20):1977. doi:10.1001/jama.2019.6511

In this narrative medicine essay, the tension stirred when a barista urges a homeless man out of an upscale coffee shop reminds an emergency department physician to consider the daily or weekly life cycles of homeless men and women who seek shelter and care in emergency departments.

Editorial

Recombinant Human Soluble Thrombomodulin in Patients With Sepsis-Associated Coagulopathy: Another Negative Sepsis Trial?

Abstract Full Text
JAMA. 2019;321(20):1978-1980. doi:10.1001/jama.2019.5792

New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research

Abstract Full Text
JAMA. 2019;321(20):1981-1982. doi:10.1001/jama.2019.5794
JAMA Insights

Women's Health

Cervical Cancer Screening: More Choices in 2019

Abstract Full Text
has audio
JAMA. 2019;321(20):2018-2019. doi:10.1001/jama.2019.4595

This JAMA Clinical Insights review summarizes recent cervical cancer screening guidelines from the USPSTF, ACOG, and ACS, and proposes an algorithm for responding to abnormal screening results in women at average risk in age group 25 to 29 and older than 30.

Clinical Update

Active Surveillance of Low-Risk Thyroid Cancer

Abstract Full Text
JAMA. 2019;321(20):2020-2021. doi:10.1001/jama.2019.5350

This JAMA Insights Clinical Update reviews use of active ultrasonography surveillance of patients with thyroid cancer as a way to postpone or avoid thyroidectomy in patients with lower-risk tumors for whom surgery is more likely to be harmful than beneficial.

JAMA Clinical Guidelines Synopsis

Colorectal Cancer Screening

Abstract Full Text
JAMA. 2019;321(20):2022-2023. doi:10.1001/jama.2019.4842

This JAMA Clinical Guidelines Synopsis summarizes the 2017 US Multi-Society Task Force on Colorectal Cancer recommendations for colorectal cancer screening.

Medical News & Perspectives

Study Puts Eggs and Dietary Cholesterol Back on the Radar

Abstract Full Text
has audio
JAMA. 2019;321(20):1959-1961. doi:10.1001/jama.2019.4165

This Medical News article is a discussion with the author of a recent study in JAMA that looked at the association of dietary cholesterol with cardiovascular disease.

Quick Uptakes

Nearly All Medications Contain Potentially Allergenic Inactive Ingredients, Analysis Shows

Abstract Full Text
has audio
JAMA. 2019;321(20):1961-1962. doi:10.1001/jama.2019.4667

This Quick Uptakes article explains that some inactive ingredients in medications can cause adverse events.

The JAMA Forum

Practical Steps to Make Health Care Better

Abstract Full Text
free access
JAMA. 2019;321(20):1962-1963. doi:10.1001/jama.2019.5985
News From the Centers for Disease Control and Prevention

Office-Related COPD

Abstract Full Text
JAMA. 2019;321(20):1966. doi:10.1001/jama.2019.5702

Kratom-Related Deaths

Abstract Full Text
JAMA. 2019;321(20):1966. doi:10.1001/jama.2019.6339
Clinical Trials Update

TAVR vs Surgery in Low-Risk Patients

Abstract Full Text
JAMA. 2019;321(20):1965. doi:10.1001/jama.2019.5992

Persistent Hashimoto Symptoms Abate With Thyroidectomy

Abstract Full Text
JAMA. 2019;321(20):1965. doi:10.1001/jama.2019.6676

CBT for Body Dysmorphic Disorder

Abstract Full Text
JAMA. 2019;321(20):1965. doi:10.1001/jama.2019.6679

More Folic Acid for Pregnant Smokers

Abstract Full Text
JAMA. 2019;321(20):1965. doi:10.1001/jama.2019.6681
Health Agencies Update

Scientists Restore Some Functions in Slaughtered Pig Brains

Abstract Full Text
JAMA. 2019;321(20):1964. doi:10.1001/jama.2019.5996

Studies Needed to Determine Costs of Untreated Behavioral Conditions

Abstract Full Text
JAMA. 2019;321(20):1964. doi:10.1001/jama.2019.6672

Medicare Advantage Expands Telehealth Services

Abstract Full Text
JAMA. 2019;321(20):1964. doi:10.1001/jama.2019.6674
Poetry and Medicine

Drift

Abstract Full Text
JAMA. 2019;321(20):2036. doi:10.1001/jama.2019.2486
JAMA Revisited

Science and Surgery

Abstract Full Text
JAMA. 2019;321(20):2037. doi:10.1001/jama.2018.15352
JAMA Patient Page

Enteral Nutrition

Abstract Full Text
free access
JAMA. 2019;321(20):2040. doi:10.1001/jama.2019.4407

This JAMA Patient Page describes use of enteral nutrition for short-term and long-term health conditions.

Comment & Response

Aircraft Cabin Hypoxia and Adverse Medical Events

Abstract Full Text
JAMA. 2019;321(20):2030. doi:10.1001/jama.2019.2369

Aircraft Cabin Hypoxia and Adverse Medical Events—Reply

Abstract Full Text
JAMA. 2019;321(20):2030-2031. doi:10.1001/jama.2019.2373

Approach to Evaluation of Multiple Liver Lesions

Abstract Full Text
JAMA. 2019;321(20):2031. doi:10.1001/jama.2019.2728

Approach to Evaluation of Multiple Liver Lesions—Reply

Abstract Full Text
JAMA. 2019;321(20):2031-2032. doi:10.1001/jama.2019.2732

Fibrinolytic Therapy to Reduce Microvascular Obstruction After Myocardial Infarction

Abstract Full Text
JAMA. 2019;321(20):2032. doi:10.1001/jama.2019.2776

Fibrinolytic Therapy to Reduce Microvascular Obstruction After Myocardial Infarction

Abstract Full Text
JAMA. 2019;321(20):2032-2033. doi:10.1001/jama.2019.2780

Fibrinolytic Therapy to Reduce Microvascular Obstruction After Myocardial Infarction—Reply

Abstract Full Text
JAMA. 2019;321(20):2033-2034. doi:10.1001/jama.2019.2784
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2019;321(20):1957-1958. doi:10.1001/jama.2018.15345
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