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October 2020 - July 1883

Decade

Year

Issue

January 29, 2019, Vol 321, No. 4, Pages 323-414

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2019;321(4):323-325. doi:10.1001/jama.2018.15168
Original Investigation

Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2019;321(4):354-363. doi:10.1001/jama.2018.21443

In this randomized trial, administration of hydrocortisone 7 to 14 days after birth had no effect on mortality or bronchopulmonary dysplasia (BPD) among mechanically ventilated very preterm infants compared with placebo.

Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease

Abstract Full Text
free access has active quiz
JAMA. 2019;321(4):364-373. doi:10.1001/jama.2018.20045

This mendelian randomization analysis compares the association of triglyceride-lowering variants in the lipoprotein lipase (LPL) gene and of LDL-C–lowering variants in the LDL receptor gene (LDLR) with coronary heart disease (CHD) risk per unit change in apolipoprotein B.

Implementation of a Health Plan Program for Switching From Analogue to Human Insulin and Glycemic Control Among Medicare Beneficiaries With Type 2 Diabetes

Abstract Full Text
free access
JAMA. 2019;321(4):374-384. doi:10.1001/jama.2018.21364

This cohort study examined associations of an intervention to encourage Medicare beneficiaries with type 2 diabetes to switch from analogue to human insulin with hemoglobin A1c1c (HBA1c) levels, serious hypoglycemic and serious hyperglycemic events, and total spending on insulin products.

Association Among County-Level Economic Factors, Clinician Supply, Metropolitan or Rural Location, and Neonatal Abstinence Syndrome

Abstract Full Text
free access
JAMA. 2019;321(4):385-393. doi:10.1001/jama.2018.20851

This population epidemiology study assesses the association of US county-level long-term unemployment, primary care and mental health clinician supply, and urban vs rural status with rates of neonatal abstinence syndrome (NAS).

Research Letter

Evidence Report

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Abstract Full Text
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JAMA. 2019;321(4):404-406. doi:10.1001/jama.2018.17847

This systematic review to support the 2019 US Preventive Services Task Force Reaffirmation Recommendation Statement on ocular prophylaxis for gonococcal ophthalmia neonatorum summarizes published evidence on the benefits and harms of ocular topical medication to prevent gonococcal conjunctival infection in newborns.

US Preventive Services Task Force

Recommendation Statement

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement

Abstract Full Text
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JAMA. 2019;321(4):394-398. doi:10.1001/jama.2018.21367

This 2019 Recommendation Statement from the US Preventive Services Task Force recommends prophylactic ocular topical medication for all newborns to prevent gonococcal ophthalmia neonatorum (A recommendation).

Viewpoint

Wearable Devices for Cardiac Rhythm Diagnosis and Management

Abstract Full Text
has audio
JAMA. 2019;321(4):337-338. doi:10.1001/jama.2018.20437

This Viewpoint discusses how the technology underlying wearable devices may lead to unclassifiable or false-positive readings of cardiac rate and rhythm, and highlights resultant uncertainties about how best to integrate the information the devices offer into clinical care to improve patients’ health.

Personal Health Records: More Promising in the Smartphone Era?

Abstract Full Text
JAMA. 2019;321(4):339-340. doi:10.1001/jama.2018.20434

This Viewpoint discusses mobile device–based personal health records, the challenges of making the devices interoperable with existing health care information systems, and the prospect that incorporation of smartphone personal health records might improve patient outcomes, lower costs, and improve health care quality.

The Role of the Advisory Committee on Immunization Practices in Ensuring Optimal Use of Vaccines

Abstract Full Text
has multimedia
JAMA. 2019;321(4):341-342. doi:10.1001/jama.2018.20792

In this Viewpoint the outgoing chair of the Advisory Committee on Immunization Practices (ACIP) reviews the history of the committee and its evolving role in making recommendations to the CDC about the best uses of vaccines in the United States.

The National Vaccine Injury Compensation Program: Striking a Balance Between Individual Rights and Community Benefit

Abstract Full Text
JAMA. 2019;321(4):343-344. doi:10.1001/jama.2018.20421

In this Viewpoint, the director and chief medical officer of the US National Vaccine Injury Compensation Program (VCIP) and colleagues review the history of and rationale for the program; explain the processes for updating injury categories and adjudicating and settling claims; and summarize the costs and success of the program in the context of the vast number of vaccine doses administered nationally.

A Piece of My Mind

Breaking the Silence

Abstract Full Text
JAMA. 2019;321(4):345-346. doi:10.1001/jama.2018.22266

In this narrative medicine essay, the author recounts her history of alcohol misuse as a response to professional anxiety and sense of imperfection and the healing quality of sharing her story with her university medical center students, trainees, and colleagues.

Editorial

The Evolving Story of Triglycerides and Coronary Heart Disease Risk

Abstract Full Text
JAMA. 2019;321(4):347-349. doi:10.1001/jama.2018.20044

Insulin Analogues for Type 2 Diabetes

Abstract Full Text
JAMA. 2019;321(4):350-351. doi:10.1001/jama.2018.21356

Structural Factors Shape the Effects of the Opioid Epidemic on Pregnant Women and Infants

Abstract Full Text
JAMA. 2019;321(4):352-353. doi:10.1001/jama.2018.20395
JAMA Insights

Clinical Update

Perioperative Glucose Control in Patients With Diabetes Undergoing Elective Surgery

Abstract Full Text
JAMA. 2019;321(4):399-400. doi:10.1001/jama.2018.20922

This Clinical Update proposes a management algorithm to prevent perioperative hyperglycemia in patients with diabetes undergoing elective surgery.

JAMA Diagnostic Test Interpretation

Serum Vascular Endothelial Growth Factor D in Cystic Lung Disease

Abstract Full Text
has active quiz
JAMA. 2019;321(4):401-402. doi:10.1001/jama.2018.20926

A 28-year-old nonsmoking woman with shortness of breath with exertion was referred to the pulmonary clinic. A computed tomographic scan of her chest revealed diffuse thin-walled pulmonary cysts without nodules, parenchymal changes, or lymphadenopathy and her serum vascular endothelial growth factor D level was 1300 pg/mL. How do you interpret the results?

Medical News & Perspectives

A Proactive Approach Needed to Combat Rising STIs

Abstract Full Text
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JAMA. 2019;321(4):330-332. doi:10.1001/jama.2018.20400

This Medical News article discusses contributing factors and proactive solutions to the recent increase in sexually transmitted diseases in the US.

The JAMA Forum

Texas v United States: The Affordable Care Act Is Constitutional and Will Remain So

Abstract Full Text
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JAMA. 2019;321(4):332-333. doi:10.1001/jama.2018.21584
News From the Centers for Disease Control and Prevention

Uterine Cancer Concern

Abstract Full Text
JAMA. 2019;321(4):336. doi:10.1001/jama.2018.21059

Secondhand Smoke Exposure

Abstract Full Text
JAMA. 2019;321(4):336. doi:10.1001/jama.2018.21345
Clinical Trials Update

Immunotherapy for Peanut Allergy Shows Promise

Abstract Full Text
JAMA. 2019;321(4):335. doi:10.1001/jama.2018.21064

Hypnotherapy Provides IBS Relief

Abstract Full Text
JAMA. 2019;321(4):335. doi:10.1001/jama.2018.22028

Novel Antibiotic Efficacious in Treating Gonorrhea

Abstract Full Text
JAMA. 2019;321(4):335. doi:10.1001/jama.2018.22029

Low-Carb Diets Help Maintain Weight Loss

Abstract Full Text
JAMA. 2019;321(4):335. doi:10.1001/jama.2018.22031

Cannabidiol May Help Normalize Brain Function in Psychosis

Abstract Full Text
JAMA. 2019;321(4):335. doi:10.1001/jama.2018.22032
Health Agencies Update

Gene Therapy for Sickle Cell Disease Shows Promise

Abstract Full Text
JAMA. 2019;321(4):334. doi:10.1001/jama.2018.21119

Missing Information in FDA Orphan Drug Application Reviews

Abstract Full Text
JAMA. 2019;321(4):334. doi:10.1001/jama.2018.22023

Geographic Variation in Substance Use–Related Inpatient Stays

Abstract Full Text
JAMA. 2019;321(4):334. doi:10.1001/jama.2018.22024
Poetry and Medicine

Brain Biopsy

Abstract Full Text
JAMA. 2019;321(4):409. doi:10.1001/jama.2018.13679
JAMA Revisited

Medicine in the New World of Peace

Abstract Full Text
JAMA. 2019;321(4):410. doi:10.1001/jama.2018.15176
JAMA Patient Page

Prevention of Gonococcal Eye Infection in Newborns

Abstract Full Text
free access
JAMA. 2019;321(4):414. doi:10.1001/jama.2018.21434

This JAMA Patient Page describes the US Preventive Services Task Force’s recent recommendations on prevention of gonococcal eye infection in newborns.

Comment & Response

Precision Medicine vs Preventive Medicine

Abstract Full Text
JAMA. 2019;321(4):406. doi:10.1001/jama.2018.18636

Precision Medicine vs Preventive Medicine—Reply

Abstract Full Text
JAMA. 2019;321(4):406-407. doi:10.1001/jama.2018.18664

Ethical Issues Involved in Grateful Patient Fundraising

Abstract Full Text
JAMA. 2019;321(4):407-408. doi:10.1001/jama.2018.18656

Ethical Issues Involved in Grateful Patient Fundraising—Reply

Abstract Full Text
JAMA. 2019;321(4):408. doi:10.1001/jama.2018.18672
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2019;321(4):327-328. doi:10.1001/jama.2018.15169
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