[Skip to Navigation]
Sign In

November 2021 - July 1883




February 5, 2019, Vol 321, No. 5, Pages 423-520

In This Issue of JAMA


Abstract Full Text
free access has audio
JAMA. 2019;321(5):423-425. doi:10.1001/jama.2018.15179
Original Investigation

Effect of Magnetic Resonance Imaging vs Conventional Treat-to-Target Strategies on Disease Activity Remission and Radiographic Progression in Rheumatoid Arthritis: The IMAGINE-RA Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA. 2019;321(5):461-472. doi:10.1001/jama.2018.21362

This randomized clinical trial compares the effect of a magnetic resonance imaging (MRI)–guided vs a conventional clinical treat-to-remission-target strategy on improving disease activity scores and radiographic progression in patients with rheumatoid arthritis (RA) in clinical remission.

Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major Surgery: The ENGAGES Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2019;321(5):473-483. doi:10.1001/jama.2018.22005

This pragmatic randomized trial compares the effects of EEG-guided anesthetic administration vs usual anesthetic care on incident postoperative delirium among older adults undergoing major surgery.

Association of Type 1 Diabetes With Standardized Test Scores of Danish Schoolchildren

Abstract Full Text
free access
JAMA. 2019;321(5):484-492. doi:10.1001/jama.2018.21819

This population-based cohort study compares standardized reading and mathematics test scores of Danish public schoolchildren with vs without type 1 diabetes to assess the association between diabetes and school performance.

Research Letter

Association Between Value-Based Incentive Programs and Catheter-Associated Urinary Tract Infection Rates in the Critical Care Setting

Abstract Full Text
free access
JAMA. 2019;321(5):509-511. doi:10.1001/jama.2018.18997

This before-after study examines the association between value-based incentive programs that link financial rewards and penalties to hospital performance on quality indicators and catheter-associated urinary tract infection outcomes in intensive care units (ICUs).


Evolving Issues in Oncology

Modernizing Clinical Trials for Patients With Cancer

Abstract Full Text
JAMA. 2019;321(5):447-448. doi:10.1001/jama.2018.18938

In this Viewpoint, directors at the National Cancer Institute (NCI) review reforms to the NCI clinical trials program, including use of historical controls and aggregating data from existing trials to improve trial efficiency, focusing on rare cancers that industry may overlook, enrolling patients based on molecular alterations instead of disease type, and establishing research facilities in underserved communities.

Assessing the Performance of Aging Surgeons

Abstract Full Text
JAMA. 2019;321(5):449-450. doi:10.1001/jama.2018.22216

This Viewpoint discusses the increasing proportion of US surgeons 55 years or older and surgical competence issues related to aging, highlights efforts to assess competence and balance patient safety with maintenance of an effective workforce, and maintains that assessment of surgical competence should be based on functional age and abilities rather than age.

HIV Viral Load and Transmissibility of HIV Infection: Undetectable Equals Untransmittable

Abstract Full Text
JAMA. 2019;321(5):451-452. doi:10.1001/jama.2018.21167

In this Viewpoint, Fauci and colleagues from NIAID review the evidence underlying the 2016 Prevention Access Campaign’s “Undetectable = Untransmittable (U = U)” HIV public health initiative, arguing that the science now supports elimination of the stigma associated with HIV infection.

Reducing the Expert Halo Effect on Pharmacy and Therapeutics Committees

Abstract Full Text
JAMA. 2019;321(5):453-454. doi:10.1001/jama.2018.20789

This Viewpoint discusses the bias experts can introduce to pharmacy and therapeutics committees tasked with evaluating the value of adding new drugs to practice formularies and proposes strategies to reduce bias including anonymous voting; allowing members time for thoughtful review; and training members in study design, critical appraisal, and cost-benefit analysis.

A Piece of My Mind

Losing Vision and Gaining Perspective

Abstract Full Text
JAMA. 2019;321(5):455-456. doi:10.1001/jama.2019.0076

In this narrative medicine essay, a researcher diagnosed with degenerative retinal disease discusses the challenge of being a scientist with a disability and describes how she worked through institutional barriers, depression, and fear with help from peers and mentors to bring insights and energy to a career focusing on vision loss in patients.


Achieving Clinical Remission for Patients With Rheumatoid Arthritis

Abstract Full Text
JAMA. 2019;321(5):457-458. doi:10.1001/jama.2018.21249

Depth of Anesthesia and Postoperative Delirium

Abstract Full Text
JAMA. 2019;321(5):459-460. doi:10.1001/jama.2019.0164
The Rational Clinical Examination

Will This Patient Be Difficult to Intubate?The Rational Clinical Examination Systematic Review

Abstract Full Text
has active quiz has multimedia has audio
JAMA. 2019;321(5):493-503. doi:10.1001/jama.2018.21413

This Rational Clinical Examination systematic review characterizes the accuracy of clinical features and bedside tests for predicting difficult endotracheal intubation.

JAMA Performance Improvement

Performing an Inadvertent Procedure

Abstract Full Text
has audio
JAMA. 2019;321(5):504-505. doi:10.1001/jama.2018.21438

This JAMA Performance Improvement article uses the case of a patient with end-stage renal disease admitted for septic shock, peritonitis, and calciphylaxis who erroneously underwent tunneled central catheter placement after he elected to pursue only hospice care to discuss unintended errors introduced by computerized order entry and opportunities for health information technology system improvements.

From The Medical Letter on Drugs and Therapeutics

Imvexxy Another Estradiol Vaginal Insert for Dyspareunia

Abstract Full Text
JAMA. 2019;321(5):506-507. doi:10.1001/jama.2018.14486

This Medical Letter review summarizes doses and formulations of Imvexxy, an estradiol softgel vaginal insert that was recently approved to treat moderate to severe dyspareunia due to vulvovaginal atrophy in postmenopausal women.

Medical News & Perspectives

American Academy of Pediatrics Says No More Spanking or Harsh Verbal Discipline

Abstract Full Text
has audio
JAMA. 2019;321(5):437-439. doi:10.1001/jama.2018.18429

This Medical News article is an interview with the coauthor of a new policy statement on corporal punishment for children.

Can Insects Compete With Beef, Poultry as Nutritional Powerhouses?

Abstract Full Text
JAMA. 2019;321(5):439-441. doi:10.1001/jama.2018.20747

In this Medical News & Perspectives article, researchers discuss insects’ potential as nutrition sources that put less stress on the environment than traditional livestock.

News From the Food and Drug Administration

Birth Control Device Essure Is Still Under the Microscope

Abstract Full Text
JAMA. 2019;321(5):444. doi:10.1001/jama.2018.21897

App Aids Treatment Retention for Opioid Use Disorder

Abstract Full Text
JAMA. 2019;321(5):444. doi:10.1001/jama.2018.21932

New Chronic Constipation Medication

Abstract Full Text
JAMA. 2019;321(5):444. doi:10.1001/jama.2018.21934
The JAMA Forum

Will State Waivers Save, Reform, or Sabotage Obamacare?

Abstract Full Text
free access
JAMA. 2019;321(5):441-442. doi:10.1001/jama.2018.21855
Bench to Bedside

Pattern of Brain Activity Linked to Low Mood in People With High Trait Anxiety

Abstract Full Text
JAMA. 2019;321(5):442-443. doi:10.1001/jama.2018.21474
The Arts and Medicine

A Neuropsychologist’s Odyssey: Lyric Experimentation Breathes Life Into Loss

Abstract Full Text
JAMA. 2019;321(5):434-435. doi:10.1001/jama.2018.20407

This Arts and Medicine essay reviews The Darker the Night, the Brighter the Stars: A Neuropsychologist’s Odyssey, a book of essays, case studies, philosophy, history, and magical realism by Oxford-trained neuropsychologist Paul Broks that explores ideas about the brain, consciousness, and sense of self.

Poetry and Medicine

The Body Is the Person

Abstract Full Text
JAMA. 2019;321(5):515. doi:10.1001/jama.2018.13365
JAMA Revisited

Is Everybody Happy?

Abstract Full Text
JAMA. 2019;321(5):516. doi:10.1001/jama.2018.15187
JAMA Patient Page

Genital Warts

Abstract Full Text
free access
JAMA. 2019;321(5):520. doi:10.1001/jama.2018.20181

This JAMA Patient Page describes genital warts and their cause, risk factors, treatment, and prevention.

Comment & Response

Palliative Care for Patients With Opioid Misuse

Abstract Full Text
has audio
JAMA. 2019;321(5):511. doi:10.1001/jama.2018.18640

Palliative Care for Patients With Opioid Misuse—Reply

Abstract Full Text
JAMA. 2019;321(5):512. doi:10.1001/jama.2018.18668

Treatment of Recurrent Clostridium difficile Infection

Abstract Full Text
JAMA. 2019;321(5):512-513. doi:10.1001/jama.2018.18993

Treatment of Recurrent Clostridium difficile Infection—Reply

Abstract Full Text
JAMA. 2019;321(5):513. doi:10.1001/jama.2018.19004

Physician Burnout

Abstract Full Text
JAMA. 2019;321(5):513-514. doi:10.1001/jama.2018.19000

Physician Burnout—Reply

Abstract Full Text
JAMA. 2019;321(5):514. doi:10.1001/jama.2018.19008
JAMA Masthead


Abstract Full Text
free access
JAMA. 2019;321(5):427-428. doi:10.1001/jama.2018.15180