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September 2019 - July 1883




February 26, 2019, Vol 321, No. 8, Pages 719-812

In This Issue of JAMA


Abstract Full Text
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JAMA. 2019;321(8):719-721. doi:10.1001/jama.2018.15212
Original Investigation

Effect of Patient-Centered Transitional Care Services on Clinical Outcomes in Patients Hospitalized for Heart Failure: The PACT-HF Randomized Clinical Trial

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JAMA. 2019;321(8):753-761. doi:10.1001/jama.2019.0710

This cluster randomized trial compares the effects of a patient-centered transitional care service intervention vs usual care on a composite outcome of all-cause readmission, emergency department (ED) visit, or death at 3 months, and a composite of all-cause readmission or ED visit at 30 days among patients hospitalized for heart failure.

Association of Overlapping Surgery With Perioperative Outcomes

Abstract Full Text
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JAMA. 2019;321(8):762-772. doi:10.1001/jama.2019.0711

This cohort study assesses the association between overlapping surgery (in which the same primary surgeon is involved in ≥2 cases simultaneously) and in-hospital mortality, in-hospital complications, and length of surgery among adult patients.

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

Abstract Full Text
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JAMA. 2019;321(8):773-785. doi:10.1001/jama.2019.0709

This case-control study investigates genetic variants associated with thiopurine-induced myelosuppression among patients of European ancestry with inflammatory bowel disease (IBD).

Research Letter

Radiation Contamination Following Cremation of a Deceased Patient Treated With a Radiopharmaceutical

Abstract Full Text
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JAMA. 2019;321(8):803-804. doi:10.1001/jama.2018.21673

This case report describes contamination of crematory equipment with lutetium Lu 177 after cremation of a patient with a pancreatic neuroendocrine tumor treated with the radioisotope 2 days prior to his death.


The Path to Diagnostic Excellence Includes Feedback to Calibrate How Clinicians Think

Abstract Full Text
JAMA. 2019;321(8):737-738. doi:10.1001/jama.2019.0113

This Viewpoint characterizes clinicians who are expert diagnosticians as well-calibrated and argues that development of diagnostic performance measures and feedback pathways could produce a better calibrated physician who would reduce patient harm from missed and delayed diagnoses, overdiagnosis, overtesting, and overtreatment.

Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning

Abstract Full Text
JAMA. 2019;321(8):739-740. doi:10.1001/jama.2019.0286

This Viewpoint discusses the forces underlying the explosion of biomarker measurement, the way the measures will likely be manipulated by market forces, and the harms that can result from overscreening and overdiagnosis, and proposes approaches to counteracting the trend, including development of standards of transparency and public registries of results to ensure that new biomarkers, for example from genetic testing and wearable devices, provide value for patients and not just profit for manufacturers.

Long-term Potential Implications of Immigration Barriers for Medical Education

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JAMA. 2019;321(8):741-742. doi:10.1001/jama.2019.0231

This Viewpoint discusses the adverse effects for the US health care system of the 2018 Presidential proclamation banning travelers from Iran, Syria, Yemen, Libya, and Somalia, including a decline in international medical graduates who provide care to a disproportionate number of socioeconomically disadvantaged patients.

A Decade of Health Information Technology Usability Challenges and the Path Forward

Abstract Full Text
JAMA. 2019;321(8):743-744. doi:10.1001/jama.2019.0161

This Viewpoint reviews the challenges of health information technology (HIT) usability since the 2009 HITECH Act promoted the adoption of electronic health records (EHRs), and proposes a 5-point plan for next advances, including a national database of usability issues and development of data-driven design standards and usability and safety measures.

Supervised Injection Facilities: Legal and Policy Reforms

Abstract Full Text
JAMA. 2019;321(8):745-746. doi:10.1001/jama.2019.0095

This Viewpoint discusses the public health rationale and benefits of supervised drug injection facilities and the legal risks to the model under US laws that prohibit sites that knowingly allow use of illicit drugs on the premises, and urges the US Department of Justice to apply science rather than criminal law in their determination of how to handle the facilities.

A Piece of My Mind

Full Circle

Abstract Full Text
JAMA. 2019;321(8):747-748. doi:10.1001/jama.2019.0584

In this narrative medicine essay, a psychiatrist used her residency to avoid grieving the loss of her brother to suicide but through participation in a grief support group during training she began to thaw enough to remember her brother, watch videos of ephemeral moments like celebrating his fourth birthday, an act that allowed her to see him and her family again.


A New Personalized, Patient-Centric, and Cost-Conscious Guideline for Contemporary Cholesterol Management

Abstract Full Text
JAMA. 2019;321(8):749-750. doi:10.1001/jama.2019.0045

Rationing of Health Care in the United States: An Inevitable Consequence of Increasing Health Care Costs

Abstract Full Text
JAMA. 2019;321(8):751-752. doi:10.1001/jama.2019.1081

Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review

Abstract Full Text
has active quiz has audio
JAMA. 2019;321(8):786-797. doi:10.1001/jama.2019.0131

This narrative review article summarizes treatment advances to aid primary care physicians who treat patients with chronic obstructive pulmonary disease.

JAMA Guide to Statistics and Methods

Number Needed to Treat: Conveying the Likelihood of a Therapeutic Effect

Abstract Full Text
JAMA. 2019;321(8):798-799. doi:10.1001/jama.2018.21971

This JAMA Guide to Statistics and Methods explains the calculations and concepts underlying the NNT as a summary statistic of effect, and the assumptions underlying the measure that affect its interpretation.

JAMA Clinical Guidelines Synopsis

Management of Blood Cholesterol

Abstract Full Text
JAMA. 2019;321(8):800-801. doi:10.1001/jama.2019.0015

This JAMA Clinical Guidelines Synopsis summarizes the 2018 American Heart Association/American College of Cardiology (AHA/ACC) guideline on management of blood cholesterol in patients with or at risk of developing atherosclerotic cardiovascular disease.

Editor's Note

Overlapping Surgery and Perioperative Outcomes

Abstract Full Text
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JAMA. 2019;321(8):772. doi:10.1001/jama.2019.1123
Medical News & Perspectives

Why Are Mothers Still Passing Syphilis to Their Babies?

Abstract Full Text
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JAMA. 2019;321(8):729-731. doi:10.1001/jama.2018.20843

This Medical News story examines why US rates of congenital syphilis reached a 20-year high in 2017.

New Cholesterol Guidelines Personalize Risk and Add Treatments

Abstract Full Text
JAMA. 2019;321(8):731-732. doi:10.1001/jama.2018.21019

This Medical News article discusses what’s new in the recently updated cholesterol clinical practice guidelines from the American Heart Association and the American College of Cardiology.

The JAMA Forum

Teaching Pelvic Examination Under Anesthesia Without Patient Consent

Abstract Full Text
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JAMA. 2019;321(8):732-733. doi:10.1001/jama.2019.0613
News From the Centers for Disease Control and Prevention

Declining Opioid Prescriptions

Abstract Full Text
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JAMA. 2019;321(8):736. doi:10.1001/jama.2019.0647

US Contraceptive Use

Abstract Full Text
JAMA. 2019;321(8):736. doi:10.1001/jama.2019.0730
Clinical Trials Update

Cessation Intervention for Low-Income Smokers

Abstract Full Text
JAMA. 2019;321(8):735. doi:10.1001/jama.2019.0684

Posters Teach the Basics of Birth Control

Abstract Full Text
JAMA. 2019;321(8):735. doi:10.1001/jama.2019.0884

Exercise for Older Adults With Cognitive Impairment

Abstract Full Text
JAMA. 2019;321(8):735. doi:10.1001/jama.2019.0885

BMI Not a Good Proxy for Breast Cancer Risk

Abstract Full Text
JAMA. 2019;321(8):735. doi:10.1001/jama.2019.0886

Digital CBT Reduces Insomnia Symptoms Round the Clock

Abstract Full Text
JAMA. 2019;321(8):735. doi:10.1001/jama.2019.0887
Health Agencies Update

Preventing EHR Confusion

Abstract Full Text
JAMA. 2019;321(8):734. doi:10.1001/jama.2019.0609

Artificial Intelligence for Cervical Precancer Screening

Abstract Full Text
JAMA. 2019;321(8):734. doi:10.1001/jama.2019.0888

Best Practices for Pain Management

Abstract Full Text
JAMA. 2019;321(8):734. doi:10.1001/jama.2019.0889
The Arts and Medicine

Filling Absence Through Medical Imaging—The Art of Marilène Oliver

Abstract Full Text
JAMA. 2019;321(8):726-727. doi:10.1001/jama.2018.21769

This Arts and Medicine essay examines the art of Marilène Oliver, who uses data from medical imaging to create works representing the human form, thereby hoping to a forge a connection between clinical data and human expression and consciousness.

Poetry and Medicine

Santa Librada

Abstract Full Text
JAMA. 2019;321(8):808. doi:10.1001/jama.2018.15969
JAMA Revisited

Feigned Amnesia as a Defense Reaction*

Abstract Full Text
JAMA. 2019;321(8):809. doi:10.1001/jama.2018.15220
JAMA Patient Page


Abstract Full Text
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JAMA. 2019;321(8):812. doi:10.1001/jama.2019.0697

This JAMA Patient Page describes the causes, symptoms, diagnosis, treatment, and prevention of leptospirosis.

Comment & Response

Thyroid Hormone Therapy for Subclinical Hypothyroidism

Abstract Full Text
JAMA. 2019;321(8):804. doi:10.1001/jama.2018.20002

Thyroid Hormone Therapy for Subclinical Hypothyroidism—Reply

Abstract Full Text
JAMA. 2019;321(8):804-805. doi:10.1001/jama.2018.20006

Arthroscopic Partial Meniscectomy vs Physical Therapy for Nonobstructive Meniscal Tears

Abstract Full Text
JAMA. 2019;321(8):805-806. doi:10.1001/jama.2018.20261

Arthroscopic Partial Meniscectomy vs Physical Therapy for Nonobstructive Meniscal Tears—Reply

Abstract Full Text
JAMA. 2019;321(8):806. doi:10.1001/jama.2018.20265

Case-Control Studies

Abstract Full Text
JAMA. 2019;321(8):806-807. doi:10.1001/jama.2018.20253

Case-Control Studies—Reply

Abstract Full Text
JAMA. 2019;321(8):807. doi:10.1001/jama.2018.20257
JAMA Masthead


Abstract Full Text
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JAMA. 2019;321(8):723-724. doi:10.1001/jama.2018.15213