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November 2019 - July 1883

Decade

Year

Issue

October 8, 2019, Vol 322, No. 14, Pages 1329-1426

In This Issue of JAMA

Highlights

Abstract Full Text
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JAMA. 2019;322(14):1329-1331. doi:10.1001/jama.2018.15542
Original Investigation

Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial

Abstract Full Text
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JAMA. 2019;322(14):1360-1370. doi:10.1001/jama.2019.14735

This randomized clinical trial compares the effects of 2 doses of sprifermin, a recombinant human fibroblast growth factor 18, vs placebo on changes in total femorotibial joint cartilage thickness in the knees of patients with osteoarthritis.

Effect of a Hospital-Initiated Program Combining Transitional Care and Long-term Self-management Support on Outcomes of Patients Hospitalized With Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial

Abstract Full Text
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JAMA. 2019;322(14):1371-1380. doi:10.1001/jama.2019.11982

This randomized clinical trial compares the effects of a hospital-initiated, nurse-delivered program combining transition of care and long-term self-management support vs transition support alone on 6-month hospitalizations and emergency department (ED) visits among patients hospitalized with chronic obstructive pulmonary disease (COPD).

Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease

Abstract Full Text
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JAMA. 2019;322(14):1381-1391. doi:10.1001/jama.2019.14120

This genetic epidemiology study uses UK Biobank database data to estimate the association between genetic variants associated with lower low-density lipoprotein cholesterol (LDL-C), lower systolic blood pressure (SBP), or both and cardiovascular disease (CVD), defined as coronary death, nonfatal, myocardial infarction, or coronary revascularization.

Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral Hemorrhage

Abstract Full Text
JAMA. 2019;322(14):1392-1403. doi:10.1001/jama.2019.13014

This meta-analysis uses individual participant data from observational studies to compare functional disability among patients with cerebellar intracerebral hemorrhage (ICH) managed with surgical hematoma evacuation vs conservative treatment.

Research Letter

Exercise Heat Stress in Patients With and Without Type 2 Diabetes

Abstract Full Text
JAMA. 2019;322(14):1409-1411. doi:10.1001/jama.2019.10943

This physiology study assesses whole-body heat loss in physically active middle-aged and older men with vs without type 2 diabetes after aerobic cycling to evaluate whether type 2 diabetes impairs heat loss and by what mechanism.

A Preliminary Study of the Effect of Dousing and Foot Immersion on Cardiovascular and Thermal Responses to Extreme Heat

Abstract Full Text
JAMA. 2019;322(14):1411-1413. doi:10.1001/jama.2019.13051

This study assesses the effects of self-dousing and foot immersion on heart rate, core temperature, and thermal discomfort of healthy volunteers randomized to simulated hot and humid vs nonhumid conditions.

Viewpoint

Communication Strategies for Sharing Prognostic Information With Patients: Beyond Survival Statistics

Abstract Full Text
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JAMA. 2019;322(14):1345-1346. doi:10.1001/jama.2019.11533

This Viewpoint discusses the challenges of communicating uncertain prognosis to patients and offers a framework and language that go past mortality statistics—addressing range of time left, loss of independence, and the unpredictability of outcomes—that embraces uncertainty and might help empower patients to plan for their quality-of-life goals.

The Law and Ethics of Fetal Burial Requirements for Reproductive Health Care

Abstract Full Text
JAMA. 2019;322(14):1347-1348. doi:10.1001/jama.2019.12713

This Viewpoint discusses the 2019 Box v Planned Parenthood US Supreme Court ruling that upheld an Indiana provision mandating that abortion facilities bury or cremate fetal remains, characterizing the law as a “targeted restriction” law intended to place undue burden on abortion providers and patients and incrementally reduce access to abortion and related reproductive health services.

Will Increasing Primary Care Spending Alone Save Money?

Abstract Full Text
JAMA. 2019;322(14):1349-1350. doi:10.1001/jama.2019.12016

This Viewpoint uses recent US state legislation mandating investments in primary care to discuss the lack of evidence supporting assumptions that primary care spending will save downstream health care costs, the reasons why that might be, and implications for policy, payment, and practice reforms.

Making Machine Learning Models Clinically Useful

Abstract Full Text
JAMA. 2019;322(14):1351-1352. doi:10.1001/jama.2019.10306

This Viewpoint reviews conventional ways of assessing performance of machine learning models to diagnose or predict outcomes, but emphasizes that if machine learning is to improve patient care the models must be evaluated for their utility in improving clinical decisions taking into account the range of decisions clinicians can take, the cost and efficacy of those options, and the likelihood that patients will follow the recommended decisions.

A Piece of My Mind

Into the Well

Abstract Full Text
JAMA. 2019;322(14):1353-1354. doi:10.1001/jama.2019.15350

In this narrative medicine essay, a psychiatrist describes the defenses he uses against the emotional toll of long days of patient care and recalls a traumatic childhood memory that helps him understand his patients’ fears and anxieties and those of their families.

Editorial

Cerebellar Intracerebral Hemorrhage: Time for Evidence-Based Treatment

Abstract Full Text
JAMA. 2019;322(14):1355-1356. doi:10.1001/jama.2019.14673

Unexpected Harm From an Intensive COPD Intervention

Abstract Full Text
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JAMA. 2019;322(14):1357-1359. doi:10.1001/jama.2019.12976
JAMA Diagnostic Test Interpretation

Point-of-Care Hemoglobin A1c

Abstract Full Text
has active quiz
JAMA. 2019;322(14):1404-1405. doi:10.1001/jama.2019.14063

An asymptomatic 57-year-old man with obesity, hypertension, and dyslipidemia requests screening for diabetes. Would you offer laboratory-based or point-of-care glucose or HbA1c testing?

From The Medical Letter on Drugs and Therapeutics

Insect Repellents

Abstract Full Text
JAMA. 2019;322(14):1406-1407. doi:10.1001/jama.2019.14373

This Medical Letter review summarizes published evidence on the safety and efficacy of commercially available insect repellents, including DEET, picaridin, and oil of lemon eucalyptus, for repelling mosquitoes, ticks, and other insects, and preventing the infections they transmit.

Editor's Note

Ensuring an Accurate Scientific Record—Retraction and Republication

Abstract Full Text
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JAMA. 2019;322(14):1380. doi:10.1001/jama.2019.14503
Medical News & Perspectives

Finding the Right Words to Stop Cancer Screening in Older Adults

Abstract Full Text
JAMA. 2019;322(14):1339-1340. doi:10.1001/jama.2019.14732

In this Medical News article, experts discuss sensitive ways to tell older adults that they no longer need cancer screening when their life expectancy is less than 10 years.

Quick Uptakes

In Hot, Humid Weather, Fans Benefit Health and Environment

Abstract Full Text
JAMA. 2019;322(14):1340-1341. doi:10.1001/jama.2019.14684

This Medical News article discusses a recent study about the effect of fans on relieving the physiological stress of high temperatures.

The JAMA Forum

Changing Minds in Health Policy

Abstract Full Text
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JAMA. 2019;322(14):1341-1342. doi:10.1001/jama.2019.15311
News From the Centers for Disease Control and Prevention

Multidrug-Resistant Salmonella

Abstract Full Text
JAMA. 2019;322(14):1344. doi:10.1001/jama.2019.15309

Mumps in Migrant Detention Centers

Abstract Full Text
JAMA. 2019;322(14):1344. doi:10.1001/jama.2019.15663
Biotech Innovations

Intubation Guidance Tool Earns Top Prize

Abstract Full Text
JAMA. 2019;322(14):1343. doi:10.1001/jama.2019.15867

Cuffless Blood Pressure Monitoring

Abstract Full Text
JAMA. 2019;322(14):1343. doi:10.1001/jama.2019.15537

Gold Nanoshells Ablate Prostate Tumors

Abstract Full Text
JAMA. 2019;322(14):1343. doi:10.1001/jama.2019.15868
The Arts and Medicine

Uncomplicated Arthroplasty—an Artist’s Perspective

Abstract Full Text
JAMA. 2019;322(14):1336-1338. doi:10.1001/jama.2019.14611

In this Arts and Medicine feature, a visual artist uses a graphic drawing “comics” format to tell the story of her knee replacement in a New York hospital.

Poetry and Medicine

Cerulean

Abstract Full Text
JAMA. 2019;322(14):1421. doi:10.1001/jama.2019.12256
JAMA Revisited

Peter Mark Roget (1779-1869): Roget’s Thesaurus

Abstract Full Text
JAMA. 2019;322(14):1422. doi:10.1001/jama.2018.15550
JAMA Patient Page

Pancreatic Cancer

Abstract Full Text
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JAMA. 2019;322(14):1426. doi:10.1001/jama.2019.14699

This JAMA Patient Page describes risks, diagnosis, and treatment of pancreatic cancer.

Comment & Response

Issues in the Adoption of Robotic Surgery

Abstract Full Text
JAMA. 2019;322(14):1413-1414. doi:10.1001/jama.2019.12180

Issues in the Adoption of Robotic Surgery—Reply

Abstract Full Text
JAMA. 2019;322(14):1414-1415. doi:10.1001/jama.2019.12188

Exercise to Prevent Falls in Older Adults

Abstract Full Text
JAMA. 2019;322(14):1415. doi:10.1001/jama.2019.12184

Exercise to Prevent Falls in Older Adults—Reply

Abstract Full Text
JAMA. 2019;322(14):1415-1416. doi:10.1001/jama.2019.12192

Identifying Sepsis Phenotypes

Abstract Full Text
JAMA. 2019;322(14):1416. doi:10.1001/jama.2019.12587

Identifying Sepsis Phenotypes

Abstract Full Text
JAMA. 2019;322(14):1416-1417. doi:10.1001/jama.2019.12591

Identifying Sepsis Phenotypes—Reply

Abstract Full Text
JAMA. 2019;322(14):1417. doi:10.1001/jama.2019.12595

Notice of Retraction. Aboumatar et al. Effect of a Program Combining Transitional Care and Long-term Self-management Support on Outcomes of Hospitalized Patients With Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial. JAMA. 2018;320(22):2335-2343.

Abstract Full Text
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JAMA. 2019;322(14):1417-1418. doi:10.1001/jama.2019.11954
Correction

Incorrect Drug Class in Text

Abstract Full Text
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JAMA. 2019;322(14):1419. doi:10.1001/jama.2019.14956

Change to Reflect Corrected Study Findings

Abstract Full Text
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JAMA. 2019;322(14):1419. doi:10.1001/jama.2019.15816

Updated Reference

Abstract Full Text
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JAMA. 2019;322(14):1419. doi:10.1001/jama.2019.16019
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2019;322(14):1333-1334. doi:10.1001/jama.2018.15543
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