This randomized clinical trial compares the effect of cryotherapy vs loop electrosurgical excision procedure (LEEP) on disease recurrence (cervical intraepithelial neoplasia [CIN] grade 2 or higher or invasive cervical cancer) in women with HIV and CIN grade 2 or 3.
This cohort study uses data from the Swedish Birth Registry to determine the prevalence of survival without major comorbidities in adulthood among persons born preterm vs full-term in Sweden between 1973 and 1997.
This randomized clinical trial compares the effects of fluoxetine vs placebo for obsessive-compulsive behaviors in children and adolescents with autism spectrum disorders.
This study discusses observed associations between limited English proficiency, revisits, and readmissions to 2 Toronto hospitals.
This Viewpoint explores the potential for plant-based meat alternatives to improve human diets, alleviate concern about the contamination that industrial meat production creates, and create a healthy and sustainable food source for the increasing global population but cautions that the health and environmental benefits remain to be proven.
This Viewpoint discusses methodological challenges to conducting reliable dietary research relative to processes and standards in place for drug discovery and development, and proposes modifications to the conduct of dietary research to improve its transparency, quality, and reliability.
In the context of “attribution gaps” that leave payers uncertain which physicians are to be credited with patient care quality and outcome measures in accountable care organization (ACO) payment models, this Viewpoint discusses the importance of patient selection of primary care providers to patient-centered value-based care, and changes CMS will need to implement to integrate the measure.
This Viewpoint discusses ethical considerations surrounding randomized clinical trials (RCTs) funded by patients who pay to enroll in them, and gaps in IRB oversight that could allow the trials to be approved despite possible patient exploitation and questionable scientific quality and social value.
In this narrative medicine essay, a clinical educator uses her experiences enduring the aftermath of treatment for acute myeloid leukemia to reflect on the difference between physician-teachers and patients’ experience of illness and to locate meaning in what she can offer her colleagues and trainees despite persistent disability.
This narrative review summarizes published evidence on the diagnosis and management of dementia, including criteria distinguishing mild cognitive impairment (MCI) from dementia, newer approaches to diagnostic testing and imaging, and nonpharmacologic and drug treatment approaches.
This JAMA Insights Clinical Update summarizes the causes, clinical manifestations, diagnosis, and treatment of patients with lactose intolerance.
This JAMA Clinical Guidelines Synopsis summarizes the 2018 American Society of Hematology guidelines for management of venous thromboembolism.
This Medical News article discusses recent findings linking subconcussive football hits to midbrain white matter damage.
This Medical News feature discusses how placebo pills, hostility, and insomnia can affect health.
This Arts and Medicine feature reviews 2 memoirs by black Americans, Hunger by Roxane Gay, and Heavy by Kiese Laymon, that reveal how early-life trauma and adverse experiences contribute to eating disorders and obesity and complicate weight management in black Americans.
This JAMA Patient Page describes lactose intolerance, its diagnosis, and its treatment.
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