This randomized clinical trial compares the effect of immediate vs delayed cord clamping on change in maternal hemoglobin in scheduled cesarean deliveries (c-sections) at term (≥37 weeks).
This post hoc analysis of a prematurely terminated randomized trial compares deaths and severe intraventricular hemorrhage among preterm infants (born at 23-31 weeks’ gestation) managed with placental transfusion via umbilical cord milking vs delayed umbilical cord clamping.
This randomized clinical trial compares the effect of 25 mg and 50 mg of ubrogepant, an oral calcitonin gene–related peptide recptor antagonist, with placebo on 2-hour pain relief among adults with migraine headaches.
This 2 × 2 factorial trial compares the effects of vitamin D3 vs placebo and omega-3 fatty acids vs placebo on change in glomerular filtration rate estimated from serum creatinine and cystatin C (eGFR) over 5 years in adults with type 2 diabetes.
This study characterizes the number and scope of state laws that protect clinicians, institutions, and others from adverse legal consequences if they refuse to participate in abortion and limitations on rights of refusal in cases of patient emergency and preservation of patients’ right to sue for injury in such cases.
This study investigates changes in in vitro fertilization (IVF) rates among health plan enrollees between 2012 and 2017 after a large US empoloyer (University of Michigan) began providing coverage for IVF in 2015.
In this Viewpoint, co-chairs of the US Department of Health and Human Services (HHS) workgroup on patient-centered reduction or discontinuation of long-term opioid analgesics summarize their 2019 guidance, including criteria for and approaches to opioid tapering; behavioral health support; and management of withdrawal symptoms, pain, and other complications.
This Viewpoint discusses the importance of developing national data systems for the study of firearm violence, and calls for investments in infrastructure and regulations to promote data availability and accessibility as an essential means to reduce the adverse public health effects of gun-related injury and mortality.
This Viewpoint discusses details of the Radiation Oncology Model, a 90-day episode-based alternative payment model proposed by the Centers for Medicare & Medicaid Services (CMS) intended to reduce inappropriate overuse of proton beam therapy, intensity-modulated radiation therapy (IMRT), and other expensive radiation oncology services.
This Viewpoint uses experience with rotavirus vaccine–induced intussusception and dengue virus vaccine–induced shock syndrome to discuss issues of disease prevalence and severity underlying recommendations the vaccines be used widely, and it reviews the systems in place to monitor vaccine safety that broadly favor vaccine benefits over risks to individuals and society.
In this narrative medicine essay, a pediatric otolaryngologist shares the story of rearing her son who has a seisure disorder and of trying to keep herself and the family together while trying not to burst or collapse.
This JAMA Insights Clinical Update discusses management options for women with vulvovaginal atrophy, focusing on the systemic safety of estrogen-based therapies and shared decision-making based on preference, cost, and adverse effect profile.
This JAMA Insights Clinical Update reviews evidence-based use of opioids to manage noncancer pain, proposing opioid-sparing pain management strategies for patients with chronic pain not yet prescribed opioids, those with chronic pain receiving opioids, and those with acute pain and not currently receiving opioid therapy.
A 62-year-old woman receiving R-CHOP chemotherapy for extranodal lymphoma had diffuse, symmetric patches and soft, thin plaques of retiform purpura on her extremities and acral surfaces. Results of physical examination and laboratory testing, including fibrinogen level and coagulation panel, were unremarkable except for leukocytosis, thrombocytopenia, and low hemoglobin count and hematocrit. What is the diagnosis and what would you do next?
This Medical News article discusses recent work aimed at using psychedelics to better understand the mind and as potential therapies for neurological and mental health disorders.
This Medical News article discusses a systematic review of studies on nutrition education in medical schools.
In this Arts and Medicine feature, a blood transfusion pathologist recounts her obsession with indie rock band Vampire Weekend and the relevance of the group’s music and work to her life and growth as a physician.
This JAMA Patient Page describes tracheostomy tube placement procedures.