This randomized trial compares the effects of 2 doses of nonlive adjuvanted recombinant zoster vaccine vs placebo on incidence of herpes zoster in adults who had undergone autologous hematopoietic stem cell transplantation.
This randomized clinical trial compares the effects on symptoms and recurrence of peroral endoscopic myotomy (POEM) vs pneumatic dilation for the initial treatment of idiopathic achalasia.
This cohort study uses Canadian registry data to investigate associations between self-reported prenatal cannabis use and preterm birth.
This study describes changes in the proportion of Medicare Part D plans requiring prior authorization for buprenorphine products before and after a 2017 FDA rquirement that the drug’s label emphasize the importance of drug treatment of opioid use disorder.
This study uses National Survey on Drug Use and Health data to examine prevalence and frequency of medical and nonmedical cannabis use among pregnant and nonpregnant women between 2013 and 2017.
This Viewpoint discusses the importance of trust in partnerships between health care and community-based organizations for achieving better health outcomes and proposes principles and strategies for building and nurturing trustworthy collaborations.
This Viewpoint discusses the historic lack of trust between health systems and underserved communities and suggests evidence-based strategies to build the trusting relationships needed to address this complex social problem.
This Viewpoint questions whether the use of race as a variable in the CKD-EPI equation to estimate glomerular filtration rate (eGFR) puts some black patients at a disadvantage with respect to renally cleared antibiotics and access to kidney transplantation, and argues that more objective clinical variables might improve the equation’s precision while avoiding problems with identifying race.
In the context of a Centers for Medicare & Medicaid Services proposal to simplify evaluation and management (E/M) documentation guidelines by 2021, this Viewpoint reviews the problems with current implementation of review-of-systems history taking in electronic health records (EHRs), including information overload, lack of follow-up of findings, clinical irrelevance to some patients and visits, and dishonesty in documentation.
In this narrative medicine essay, a surgeon and palliative care physician describes the isolating silence that she felt her after the slaying of her father in Egypt when she was 18 years old and how that lingering silence has come to guide her when sitting with patients, when there are no words.
This narrative review summarizes causes of subclinical hyperthyroidism, reviews controversies related to its clinical significance as a risk factor for heart failure, ischemic heart disease, and dementia, and discusses management considerations, including indications for observation vs thyroid hormone supplementation.
This JAMA Clinical Guidelines Synopsis summarizes the 2017 American College of Cardiology/American Heart Association/Heart Rhythm Society guideline on management of patients with ventricular arrhythmias and prevention of sudden cardiac death.
A 65-year-old man from Vietnam presented with shortness of breath at rest, orthopnea, and lower extremity edema for the past 2 weeks and nonproductive cough and weight loss for the past 4 months. A computed tomographic (CT) scan demonstrated a moderate to large pericardial effusion that was lymphocyte-predominant with a fluid ADA level of 118.1 U/L. What would you do next?
This Medical News story examines the debate over the value of checkups for healthy individuals.
This Medical News article explains how Burmese pythons, singing mice, and the African leopard tortoise may help researchers better understand several debilitating health conditions.
This JAMA Patient Page describes subclinical hypothyroidism and its causes, symptoms, and treatment.