This cohort study investigates the association between gluten intake in the first 5 years of life and celiac disease autoimmunity and biopsy-confirmed celiac disease in genetically at-risk children over a median 9-year follow-up.
This substudy of the SPRINT randomized clinical trial evaluates the association between intensive (systolic blood pressure <120 mm Hg) vs standard (<140 mm Hg) blood pressure control and changes in cerebral white matter lesion and total brain volumes among hypertensive adults.
Over 24 years plus follow-up, this community-based cohort study monitored individuals categorized by midlife and late-life blood pressure levels to evaluate association between blood pressure levels and incident dementia.
This cohort study examines the association between long-term exposure to ambient ozone, black carbon, and other air pollutants and progression of CT-defined percent emphysema and decline in lung function in adults in 6 US metropolitan regions.
This study uses Medicare billing codes to characterize trends in readmission and mortality rates for Medicare fee-for-service beneficiaries with pulmonary embolism (PE) between 1999 and 2015 to assess changes accompanying recent diagnostic and therapeutic changes in management of the disease.
This study uses IM-ITE survey data to characterize the proportion of internal medicine residents in 2016 who self-reported having been bullied during their residency training.
This Viewpoint discusses the use of artificial intelligence in health care and its potential effect on how patients access care and how physicians and patients make decisions.
This Viewpoint reviews new findings presented at a 2019 NIH conference about neuroendocrine, metabolic, immunologic, and physiologic abnormalities that contribute to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
This Viewpoint argues that buprenorphine be made available without prescription behind the counter at retail pharmacies with age and quantity restrictions similar to those used for pseudoephedrine, and addresses concerns raised by the access model about safety and diversion.
This Viewpoint argues for thinking about improvements in the care of new moms and infants as a single entity, and discusses regionalization of obstetric and infant care as a way to operationalize the idea and achieve simultaneous improvements in maternal and neonatal outcomes.
In this narrative medicine essay, a pediatrician realizes after her infant daughter undergoes treatment for elevated bilirubin that until then her advice to new parents may have interfered with the infant-mother bond yet forgives herself the distress she may have caused.
This narrative review summarizes the mechanisms and set-up of extracorporeal life support (ECLS) including extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R), its indications, complications, goals of treatment, and the need to build on evidence base for the intervention so it is used nationally and in a standardized fashion.
This JAMA Insights Clinical Update reviews bone turnover markers measurable in blood and urine and summarizes evidence supporting their use to predict osteoporosis and osteoporotic fractures, assess treatment adherence and efficacy, and monitor bone loss after drug discontinuation.
A 41-year-old woman with an 8–pack-year history of tobacco use had 4 years of progressive cough and dyspnea. She had no history of neonatal respiratory distress or nasal congestion and no family history of COPD or cystic fibrosis; pulmonary function testing showed a severe obstruction and chest CT showed lower lobe predominant emphysema and bronchiectasis. What is the diagnosis and what would you do next?
In this Medical News article, experts discuss an association between the Netflix series 13 Reasons Why and increases in adolescent suicides, suicide attempts, and suicide-related hospital admissions.
This Medical News article discusses a recent study in JAMA Internal Medicine on the association of daily steps with all-cause mortality.
In this Arts and Medicine feature, author Samuel Shem (pen name of Stephen Bergman, MD) reflects on the origins of his classic novel The House of God, the people and events that inspired its stories, the notion of “fiction as resistance,” and the evolving meaning of the book given developments in medicine and medical education in the 40 years since its publication.
In this Arts and Medicine feature, an early-career physician discusses the ongoing relevance of Samuel Shem’s novel, The House of God, to contemporary health care and medical education on the occasion of its 40th anniversary of publication.
This JAMA Patient Page describes small kidney tumor diagnoses and treatment options.
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