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January 2021 - July 1883




January 7, 2020, Vol 323, No. 1, Pages 11-100

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2020;323(1):e1920739. doi:10.1001/jama.2019.20739
Original Investigation

Effect of Folic Acid and Zinc Supplementation in Men on Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2020;323(1):35-48. doi:10.1001/jama.2019.18714

This randomized clinical trial compares the effect of folic acid and elemental zinc vs placebo on semen quality in men and live birth among US couples planning infertility treatment.

Association of Powder Use in the Genital Area With Risk of Ovarian Cancer

Abstract Full Text
free access has active quiz
JAMA. 2020;323(1):49-59. doi:10.1001/jama.2019.20079

This cohort study uses pooled data from 4 cohorts to estimate associations between perineal use of body powder and ovarian cancer in US women.

Effect of Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2020;323(1):60-69. doi:10.1001/jama.2019.19997

This randomized clinical trial compared the effectiveness of talc poudrage administered during thoracoscopy with local anesthesia vs talc slurry delivered via chest tube placement with local anesthesia in successfully inducing pleurodesis in patients with malignant pleural effusion.

Research Letter

Changes in Utilization of Generic Angiotensin Receptor Blockers Following Product Recalls in the United States

Abstract Full Text
free access
JAMA. 2020;323(1):87-89. doi:10.1001/jama.2019.17521

This pharmacoepidemiology study uses claims data to characterize angiotensin receptor blocker (ARB) prescription trends to evaluate whether recalls of ARBs prompted by discovery of potentially carcinogenic impurities shifted utilization of ARBs individually and as a drug class.

Trends in Cesarean Delivery Rates in China, 2008-2018

Abstract Full Text
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JAMA. 2020;323(1):89-91. doi:10.1001/jama.2019.17595

This study uses China’s National Maternal and Child Health Statistics data set to characterize trends in cesarean delivery rates overall and by urban and rural areas in China between 2008 and 2018.

Special Communication

Practices to Foster Physician Presence and Connection With Patients in the Clinical Encounter

Abstract Full Text
has active quiz has multimedia has audio
JAMA. 2020;323(1):70-81. doi:10.1001/jama.2019.19003

This study uses systematic reviews, interviews, and an expert consensus process to identify practices that promote clinician presence and connection during patient visits: preparation and listening with intent, agreeing on what matters most, connecting with the patient’s story, and exploring emotional cues.


Comorbidities in Persons With HIV: The Lingering Challenge

Abstract Full Text
has audio
JAMA. 2020;323(1):19-20. doi:10.1001/jama.2019.19775

In this Viewpoint, Anthony Fauci and NIAID colleagues discuss the challenge of managing comorbidities in persons living with HIV with an emphasis on the long-term risk and burden of cardiovascular disease, kidney and hepatic disease, and neurocognitive disorders in an infected population approaching normal longevity while receiving long-term antiretroviral therapy.

Moving Toward Evidence-Based Policy: The Value of Randomization for Program and Policy Implementation

Abstract Full Text
JAMA. 2020;323(1):21-22. doi:10.1001/jama.2019.18061

This Viewpoint emphasizes the value of randomized evaluation of policies and programs designed to improve health behaviors, health outcomes, and health care delivery, and articulates preconditions that appear to be essential for the practice to become more of a standard in policy implementation.

Alcohol and Cancer Risk: Clinical and Research Implications

Abstract Full Text
JAMA. 2020;323(1):23-24. doi:10.1001/jama.2019.19133

This Viewpoint reviews the epidemiologic evidence documenting the association between alcohol consumption and cancer risk, and calls for possible health responses and research into interventions for decreasing overall alcohol consumption as a means of reducing cancer risk.

Identifying and Preventing Adverse Childhood Experiences: Implications for Clinical Practice

Abstract Full Text
has active quiz
JAMA. 2020;323(1):25-26. doi:10.1001/jama.2019.18499

This Viewpoint uses findings from a 2019 Centers for Disease Control and Prevention (CDC) report detailing the prevalence and long-term harms of adverse childhood experiences (ACEs) to emphasize ways pediatricians can identify patients experiencing ACEs and intervene to prevent or reduce harms associated with the experiences.

A Piece of My Mind

Primarily Care

Abstract Full Text
JAMA. 2020;323(1):27-28. doi:10.1001/jama.2019.20065

In this narrative medicine essay, a retiring internist remembers the changes and challenges during his 40-year career and counts as his most rewarding moments the times his patients said that they felt listened to, respected, and supported.


Use of Powder in the Genital Area and Ovarian Cancer Risk: Examining the Evidence

Abstract Full Text
JAMA. 2020;323(1):29-31. doi:10.1001/jama.2019.20674

Can an Evidence-Based Approach Improve the Patient-Physician Relationship?

Abstract Full Text
has multimedia has audio
JAMA. 2020;323(1):31-32. doi:10.1001/jama.2019.19427

Connecting With Patients—The Missing Links

Abstract Full Text
has multimedia has audio
JAMA. 2020;323(1):33-34. doi:10.1001/jama.2019.20153
JAMA Clinical Challenge

Painful and Pruritic Blisters on the Lower Lip

Abstract Full Text
has active quiz
JAMA. 2020;323(1):82-83. doi:10.1001/jama.2019.17568

A 41-year-old woman had a 2-day history of burning, stinging, itchy blisters on and around the lower lip; similar blisters had resolved spontaneously 1 year ago. She was well-appearing and afebrile; apart from occasional ibuprofen use, she took no medications. What is the diagnosis and what would you do next?

From The Medical Letter on Drugs and Therapeutics

Influenza Vaccine for 2019-2020

Abstract Full Text
has multimedia has audio
JAMA. 2020;323(1):84-85. doi:10.1001/jama.2019.18016

This Medical Letter review summarizes types and use of commercially available inactivated and activated trivalent and quadrivalent influenza vaccines, with recommendations for which to use in patients who are pregnant, allergic, or immunocompromised.

Medical News & Perspectives

Matters of the Mind—Bedtime Procrastination, Relaxation-Induced Anxiety, Lonely Tweeters

Abstract Full Text
JAMA. 2020;323(1):15-16. doi:10.1001/jama.2019.20014

This Medical News article offers new insights into smartphones and bedtime, why relaxation may be stressful, and Twitter as a loneliness indicator.

News From the Food and Drug Administration

Ear Tubes Can Be Inserted With Local Anesthesia

Abstract Full Text
JAMA. 2020;323(1):18. doi:10.1001/jama.2019.20951

New Option for Sickle Cell Disease

Abstract Full Text
JAMA. 2020;323(1):18. doi:10.1001/jama.2019.20640

Novel Alternative for Partial-Onset Seizures

Abstract Full Text
JAMA. 2020;323(1):18. doi:10.1001/jama.2019.20952
Bench to Bedside

New Flu Antiviral Candidate May Thwart Drug Resistance

Abstract Full Text
JAMA. 2020;323(1):17. doi:10.1001/jama.2019.20225

This Medical News article discusses an investigational influenza treatment that could overcome the growing problem of drug resistance.

Poetry and Medicine

Keep That Same Energy

Abstract Full Text
JAMA. 2020;323(1):95. doi:10.1001/jama.2019.19207
JAMA Revisited

The Teaching of Clinical Medicine

Abstract Full Text
JAMA. 2020;323(1):96. doi:10.1001/jama.2019.13246
JAMA Patient Page

Medications for Treating Infection

Abstract Full Text
free access
JAMA. 2020;323(1):100. doi:10.1001/jama.2019.17387

This JAMA Patient Page describes the types of medications used to treat infections, with a focus on antibiotics and antibiotic resistance.

Comment & Response

Enhancing Compassion in Medical Students

Abstract Full Text
JAMA. 2020;323(1):91. doi:10.1001/jama.2019.18141

Enhancing Compassion in Medical Students

Abstract Full Text
JAMA. 2020;323(1):91. doi:10.1001/jama.2019.18144

Enhancing Compassion in Medical Students—Reply

Abstract Full Text
JAMA. 2020;323(1):91-92. doi:10.1001/jama.2019.18150

High-Dose Vitamin D Supplementation and Bone Health

Abstract Full Text
JAMA. 2020;323(1):92. doi:10.1001/jama.2019.18138

High-Dose Vitamin D Supplementation and Bone Health

Abstract Full Text
JAMA. 2020;323(1):92-93. doi:10.1001/jama.2019.18147

High-Dose Vitamin D Supplementation and Bone Health—Reply

Abstract Full Text
JAMA. 2020;323(1):93-94. doi:10.1001/jama.2019.18153
JAMA Masthead


Abstract Full Text
free access
JAMA. 2020;323(1):11-12. doi:10.1001/jama.2019.13239