This randomized clinical trial compares the effects of 2 tenecteplase doses (0.40 vs 0.25 mg/kg) prior to endovascular thrombectomy on blood flow restoration to brain ischemic territory in patients with large vessel occlusion ischemic stroke.
This randomized trial compares the effect of doxorubicin plus olaratumab vs doxorubicin plus placebo on overall survival in patients with advanced/metastatic soft tissue sarcoma and leiomyosarcoma.
This population epidemiology study used Swedish histopathology registry data to estimate mortality risk in patients with vs without celiac disease.
This study characterizes the demographic, epidemiologic, and clinical characteristics of hospitalized infants diagnosed with coronavirus disease 2019 infection between December 8, 2019, and February 6, 2020, in China.
This study characterizes annual changes in enrollment of Medicare and non-Medicare patients treated at dialysis facilities before and after 2011 payment reforms and 2014 Affordable Care Act changes that influenced reimbursements.
This 2020 Recommendation Statement from the US Preventive Services Task Force recommends against screening for bacterial vaginosis (BV) in pregnant persons not at increased risk for preterm delivery (D recommendation) and concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for BV in pregnant persons at increased risk for preterm delivery (I statement).
This systematic review to support the 2020 US Preventive Services Task Force Recommendation Statement on screening for bacterial vaginosis (BV) summarizes published evidence on the benefits and harms of BV screening and treatment in pregnant adolescents and adults to prevent preterm delivery.
This Viewpoint summarizes key epidemiologic and clinical findings from all cases of coronavirus disease 2019 (COVID-19) reported through February 11, 2020, in mainland China, and case trends in response to government attempts to control and contain the infection.
This Viewpoint discusses public health measures implemented in Singapore to manage potential COVID-19 infection based on the country’s experience with SARS in 2003 and reviews critical information gaps necessary to help manage the outbreak, such as viral shedding patterns and optimal timing of antiviral treatment after exposure.
This Viewpoint discusses the potential role of ECMO (extracorporeal membrane oxygenation) in the management of novel coronavirus disease 2019 (COVID-19) and cautions about the risk of overuse and the shortage of ECMO capability given the numbers of people infected if the technology is not appropriately utilized.
This Viewpoint proposes that framing climate change as a human health crisis could accelerate climate action, and reviews evidence pointing toward the health benefits of transitioning to renewable energy, plant-based diets, and a global lower carbon footprint.
In this narrative medicine essay, a pediatrician describes how a 2-year-old’s game of peekaboo expresses her bewilderment and grief at the death of her twin brother.
This Medical Letter review summarizes mechanisms of action and evidence of effects of Aklief, a 0.005% topical cream approved in 2019 for treatment of acne vulgaris in patients aged 9 years or older.
This Medical News story examines the status of Makena, the only drug approved for the indication of preventing preterm birth.
This Medical News series offers an occasional roundup of developments in cardiovascular medicine.
This JAMA Patient Page describes the US Preventive Services Task Force’s recent recommendations for screening for bacterial vaginosis during pregnancy.