This randomized trial compares the effects of intravenous zoledronic acid vs placebo on magnetic resonance imaging–assessed knee cartilage volume loss in patients with symptomatic knee osteoarthritis and subchondral bone marrow lesions.
This study characterizes use of continuous pulse oximetry monitoring in hospitalized children with bronchiolitis who do not require supplemental oxygen in Canadian and US hospitals.
This study characterizes the point prevalence and outcomes of infection among adult patients treated at international intensive care units during a 24-hour period.
This case series describes the epidemiologic features, clinical presentation, treatment, and outcomes of the first 18 patients with confirmed coronavirus disease 2019 (COVID-19) in Singapore
This case series describes reverse transcriptase–polymerase chain reaction (RT-PCR) test results in 4 health professionals discharged from hospitalization or quarantine after 2 negative RT-PCR test results and resolution of clinical COVID-19 infection.
This study uses internet search data to identify and characterize biomedical and health sciences faculty at US higher education institutions who had sexual misconduct accusations against them between 1982 and 2019 that led to institutional or legal actions proving or supporting guilt.
This Viewpoint explains the technical and regulatory challenges that hampered diagnostic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the early spread of infection in the US and considers the unintended consequences of making testing more widely available, including false-negative results and overtesting.
This Viewpoint discusses the importance of protecting health care workers caring for patients with coronavirus disease 2019 (COVID-19) and measures that can be taken in and out of the hospital to prevent their and their families’ exposure to SARS-CoV-2.
This Viewpoint discusses Kaiser Permanente in Northern California’s transition from a containment strategy for coronavirus disease 2019 (COVID-19)—isolation or quarantine of exposed or infected patients—to a mitigation strategy comprising elements such as droplet and airborne precautions, telemedicine, staffing protocol revisions, and equipment allocation planning.
This Viewpoint summarizes current shortcomings in direct-to-consumer genetic tests, which often lack clinical utility for consumers, and explains how tests that encompass entire genes and include only genes with well-established risk estimates and medical management guidelines could provide more valuable insight into their disease risk.
This Viewpoint discusses gaps between the growth of direct-to-consumer genomic testing and knowledge about how best to use the information, highlighting the absence of diversity in genetic databases, the scarcity of accompanying genetic counseling, and data security and privacy concerns.
In this narrative medicine essay, a cardiologist recalls the effects his wife’s death had on his young family and the humility he brings to being with patients in their traumas as a result.
This JAMA Insights article summarizes the subjective cognitive problems experienced by some women during perimenopause (menopausal transition) and provides guidance to physicians on how to effectively answer patients’ questions and recognize when these symptoms may require clinical intervention.
This JAMA Clinical Insights article reviews the diagnosis and treatment of chronic tinnitus based on current understanding of symptom mechanisms and emphasizes the importance of behavioral therapies (tinnitus retraining) and personalized treatment whenever possible.
This JAMA Insights article reviews care for the most severely ill patients with coronavirus disease 2019 (COVID-19), including standards of management of ARDS, preventing SARS-CoV-2 spread in health care settings, and surge preparation.
This Medical News story examines the question of whether some melanomas might be better left undetected.
This Medical News article is an interview with FDA scientist David Strauss, MD, PhD, about his recent studies in JAMA investigating sunscreen safety.
This JAMA Patient Page describes how coronavirus disease 2019 (COVID-19) is spread and measures people can take to avoid acquiring COVID-19.
This JAMA Patient Page describes the purpose and proper use of medical masks for prevention of respiratory infection.
Notice of Retraction and Replacement. Gander et al. Association between dialysis facility ownership and access to kidney transplantation. JAMA. 2019;322(10):957-973