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July 2021 - July 1883

Decade

Year

Issue

May 19, 2020, Vol 323, No. 19, Pages 1873-1982

In This Issue of JAMA

Audio Highlights

Abstract Full Text
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JAMA. 2020;323(19):e200021. doi:10.1001/jama.2020.0021
Original Investigation

Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China

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JAMA. 2020;323(19):1915-1923. doi:10.1001/jama.2020.6130

This population epidemiology study examines associations between phases of nonpharmaceutical public health interventions (social distancing, centralized quarantine, home confinement, and others) and rates of laboratory-confirmed COVID-19 infection in Wuhan, China, between December 2019 and early March 2020.

Associations Between Maternal Antenatal Corticosteroid Treatment and Mental and Behavioral Disorders in Children

Abstract Full Text
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JAMA. 2020;323(19):1924-1933. doi:10.1001/jama.2020.3937

This population cohort study uses national Finnish birth registry data to assess associations between antenatal corticosteroid treatment to accelerate fetal maturation and mental and behavioral disorders in term and preterm children.

Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis

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JAMA. 2020;323(19):1934-1944. doi:10.1001/jama.2020.4249

This systematic review and meta-analysis examines whether blood pressure lowering is associated with a reduced risk of dementia or cognitive impairment.

Research Letter

Community Prevalence of SARS-CoV-2 Among Patients With Influenzalike Illnesses Presenting to a Los Angeles Medical Center in March 2020

Abstract Full Text
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JAMA. 2020;323(19):1966-1967. doi:10.1001/jama.2020.4958

This study characterizes the prevalence of reverse-transcriptase polymerase chain reaction results positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among patients presenting with influenzalike illness who underwent nasopharyngeal swab testing for influenza and respiratory syncytial virus over 4 days in March 2020.

Sample Pooling as a Strategy to Detect Community Transmission of SARS-CoV-2

Abstract Full Text
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JAMA. 2020;323(19):1967-1969. doi:10.1001/jama.2020.5445

This study describes findings of novel coronavirus testing on pooled nasopharyngeal and bronchoalveolar lavage samples taken from patients who had negative results by routine respiratory virus testing to see if pooling samples could increase testing throughput and efficiency and facilitate early detection of community COVID-19 transmission.

Seasonal Influenza Activity During the SARS-CoV-2 Outbreak in Japan

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JAMA. 2020;323(19):1969-1971. doi:10.1001/jama.2020.6173

This study uses data from the National Institutes of Infectious Diseases Japan to compare weekly influenza activity in the 2019/2020 vs the 2014-2019 seasons given mitigation strategies taken in 2020 to limit the spread of COVID-19.

Coverage for Biosimilars vs Reference Products Among US Commercial Health Plans

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JAMA. 2020;323(19):1972-1973. doi:10.1001/jama.2020.2229

This study uses US commercial health plan insurance data to characterize coverage for biosimilar drugs compared with reference products.

Viewpoint

COVID-19: Beyond Tomorrow

From Mitigation to Containment of the COVID-19 Pandemic: Putting the SARS-CoV-2 Genie Back in the Bottle

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JAMA. 2020;323(19):1889-1890. doi:10.1001/jama.2020.6572

This Viewpoint discusses public health strategies necessary for the US to relax its mitigation strategies—most notably expanded testing, isolation, and contact-tracing in ways that avoid stigmatization of vulnerable populations—and proposes investing returns from a reopened economy to finance testing and public health infrastructure.

COVID-19 and African Americans

Abstract Full Text
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JAMA. 2020;323(19):1891-1892. doi:10.1001/jama.2020.6548

This Viewpoint discusses the long history of racial inequities that cause black populations in US cities to bear a disproportionate burden of COVID-19 illness and mortality and calls for a renewed commitment to eliminating disparities that have been made so starkly visible by the pandemic.

Predictive Mathematical Models of the COVID-19 Pandemic: Underlying Principles and Value of Projections

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JAMA. 2020;323(19):1893-1894. doi:10.1001/jama.2020.6585

This Viewpoint discusses the challenges of accurately modeling the COVID-19 pandemic and reviews principles that will make some models more useful than others, such as use of granular local data when available, regular updating and revision, and specification of uncertainty around estimates.

Optimizing the Trade-off Between Learning and Doing in a Pandemic

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JAMA. 2020;323(19):1895-1896. doi:10.1001/jama.2020.4984

This Viewpoint discusses the tensions between evaluating treatments (learning) and just treating patients (doing) during the coronavirus disease 2019 (COVID-19) pandemic, and proposes actions the clinical research and practice communities can take to support each other’s imperatives so that both can “learn from doing” in a more integrated patient care approach.

Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics

Abstract Full Text
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JAMA. 2020;323(19):1897-1898. doi:10.1001/jama.2020.4742

This Viewpoint uses the absence of known effective treatment for Ebola virus disease to emphasize the costs of off-label and compassionate drug use during an infectious disease outbreak and the importance of establishing the efficacy and safety of promising drug leads in randomized trials to inform their clinical use.

Finding Effective Treatments for COVID-19: Scientific Integrity and Public Confidence in a Time of Crisis

Abstract Full Text
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JAMA. 2020;323(19):1899-1900. doi:10.1001/jama.2020.6434

This Viewpoint discusses the risks to patients and public health posed by the FDA’s politically pressured Emergency Use Authorization (EUA) of chloroquine and hydroxychloroquine for COVID-19 treatment, and proposes principles to follow to ensure new therapies are studied properly and quickly to maximize benefits and minimize risks to patients.

Potential Legal Liability for Withdrawing or Withholding Ventilators During COVID-19: Assessing the Risks and Identifying Needed Reforms

Abstract Full Text
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JAMA. 2020;323(19):1901-1902. doi:10.1001/jama.2020.5442

This Viewpoint discusses the legal risks to health care workers and hospital systems from withdrawing or withholding ventilation from COVID-19 patients and cites a Maryland statute that offers legal immunity to clinicians making good faith decisions under emergency conditions as an example for other states to follow.

Increasing Access to FDA Inspection Reports on Irregularities and Misconduct in Clinical Trials

Abstract Full Text
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JAMA. 2020;323(19):1903-1904. doi:10.1001/jama.2020.1631

This Viewpoint reviews notable examples of clinical trial misconduct identified by routine US Food and Drug Administration (FDA) clinical trial site inspections and argues that making inspection reports publicly available on the agency’s and trial registry websites is important to maintaining the integrity of clinical research.

A Piece of My Mind

Failing Another National Stress Test on Health Disparities

Abstract Full Text
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JAMA. 2020;323(19):1905-1906. doi:10.1001/jama.2020.6547

This narrative medicine essay emphasizes the undue disease burden carried by minority populations in the COVID-19 pandemic and proposes collection and reporting of data by race/ethnicity and multilingual targeted educational efforts delivered by celebrities or faith leaders as first steps to reduce the imbalance.

Editorial

COVID-19: Beyond Tomorrow

COVID-19—Looking Beyond Tomorrow for Health Care and Society

Abstract Full Text
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JAMA. 2020;323(19):1907-1908. doi:10.1001/jama.2020.6582

Public Health Interventions for COVID-19: Emerging Evidence and Implications for an Evolving Public Health Crisis

Abstract Full Text
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JAMA. 2020;323(19):1908-1909. doi:10.1001/jama.2020.5910

Antenatal Corticosteroids—Too Much of a Good Thing?

Abstract Full Text
JAMA. 2020;323(19):1910-1912. doi:10.1001/jama.2020.3935

Conserving Supply of Personal Protective Equipment—A Call for Ideas

Abstract Full Text
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JAMA. 2020;323(19):1911. doi:10.1001/jama.2020.4770

Sourcing Personal Protective Equipment During the COVID-19 Pandemic

Abstract Full Text
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JAMA. 2020;323(19):1912-1914. doi:10.1001/jama.2020.5317
Review

Pathophysiology, Clinical Presentation, and Treatment of Psoriasis: A Review

Abstract Full Text
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JAMA. 2020;323(19):1945-1960. doi:10.1001/jama.2020.4006

This narrative review summarizes current evidence regarding the pathogenesis, clinical presentation, diagnosis, and treatments of plaque psoriasis.

JAMA Insights

Management of Kidney Stones in 2020

Abstract Full Text
JAMA. 2020;323(19):1961-1962. doi:10.1001/jama.2020.0662

This JAMA Insights Clinical Update reviews the diagnosis and management of kidney stones and proposes a treatment algorithm based on imaging findings, symptom control, and risk of recurrence.

From The Medical Letter on Drugs and Therapeutics

Drospirenone (Slynd)A New Progestin-Only Oral Contraceptive

Abstract Full Text
JAMA. 2020;323(19):1963-1964. doi:10.1001/jama.2020.1603

This Medical Letter review summarizes the mechanism of action and drug interactions of drospirenone, a new progestin-only oral contraceptive, and compares it with norethindrone, its competitor.

Medical News & Perspectives

The Promise and Peril of Antibody Testing for COVID-19

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JAMA. 2020;323(19):1881-1883. doi:10.1001/jama.2020.6170

This Medical News article discusses how antibody tests should—and should not—be used during the SARS-CoV-2 pandemic.

News From the Food and Drug Administration

Therapy Approved for Hard-to-Treat Upper Tract Urothelial Cancer

Abstract Full Text
JAMA. 2020;323(19):1887. doi:10.1001/jama.2020.7153

A New Treatment for Children With Neurofibromatosis Type 1

Abstract Full Text
JAMA. 2020;323(19):1887. doi:10.1001/jama.2020.7157

Generic Albuterol Inhaler Approved

Abstract Full Text
JAMA. 2020;323(19):1887. doi:10.1001/jama.2020.7282
The JAMA Forum

Time to Consider a New Look at Physician-Owned Hospitals to Increase Competition in Health Care?

Abstract Full Text
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JAMA. 2020;323(19):1884-1885. doi:10.1001/jama.2020.6106
Global Health

WHO: Strengthen Nurse Workforce

Abstract Full Text
JAMA. 2020;323(19):1886. doi:10.1001/jama.2020.6430

Study Suggests a Second Patient Has Been Cured of HIV

Abstract Full Text
JAMA. 2020;323(19):1886. doi:10.1001/jama.2020.7626

Studies Explore HIV Treatment and Prevention in Pregnant Women

Abstract Full Text
JAMA. 2020;323(19):1886. doi:10.1001/jama.2020.7627
The Arts and Medicine

Infectious Disease Outbreaks, Pandemics, and Hollywood—Hope and Fear Across a Century of Cinema

Abstract Full Text
JAMA. 2020;323(19):1878-1880. doi:10.1001/jama.2020.7187

This Arts and Medicine feature tallies the appearance of infectious disease outbreaks in cinema since 1914, and identifies common themes, such as stigmatization and physician heroism, that characterize the films.

Poetry and Medicine

The Sound of Grief

Abstract Full Text
JAMA. 2020;323(19):1977. doi:10.1001/jama.2020.1307
JAMA Revisited

The Bubonic Plague in San Francisco

Abstract Full Text
JAMA. 2020;323(19):1978. doi:10.1001/jama.2019.13444
JAMA Patient Page

Testing Individuals for Coronavirus Disease 2019 (COVID-19)

Abstract Full Text
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JAMA. 2020;323(19):1981. doi:10.1001/jama.2020.5388

This JAMA Patient Page describes the test for coronavirus disease 2019 (COVID-19), current guidelines for determining who should be tested, reasons for slow adoption of testing in the US, and potential drawbacks of alternate tests.

Food Safety and COVID-19

Abstract Full Text
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JAMA. 2020;323(19):1982. doi:10.1001/jama.2020.5877

This JAMA Patient Page describes how the novel coronavirus that causes COVID-19 is transmitted and provides measures people can take while grocery shopping, unpacking groceries, and preparing food to minimize the risk of being infected.

Comment & Response

Cognitive Screening of Older Practitioners

Abstract Full Text
JAMA. 2020;323(19):1973-1974. doi:10.1001/jama.2020.4257

Cognitive Screening of Older Practitioners

Abstract Full Text
JAMA. 2020;323(19):1974-1975. doi:10.1001/jama.2020.4260

Cognitive Screening of Older Practitioners—Reply

Abstract Full Text
JAMA. 2020;323(19):1975. doi:10.1001/jama.2020.4266

Balancing Past vs Future Values in Decision-making

Abstract Full Text
JAMA. 2020;323(19):1975-1976. doi:10.1001/jama.2020.3830

Balancing Past vs Future Values in Decision-Making—Reply

Abstract Full Text
JAMA. 2020;323(19):1976. doi:10.1001/jama.2020.3837
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2020;323(19):1873-1874. doi:10.1001/jama.2019.13437
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