This randomized clinical trial compares the effect of a patient-centered decision support tool vs usual care on rates of trial of labor among women with a previous cesarean delivery.
This randomized trial compares the effects of C-reactive protein (CRP)–guided antibiotic duration (discontinuation once CRP declined by 75% of peak value) vs fixed 7- vs 14-day durations on 30-day clinical failure rate among patients with gram-negative bacteremia.
This cohort study estimates associations between intravenous tissue plasminogen activator (tPA) door-to-needle times of less than 4.5 hours for acute ischemic stroke and 1-year mortality or readmission among Medicare beneficiaries aged 65 years or older.
This study characterizes the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection detected on polymerase chain reaction (PCR) screening of a large homeless shelter population in Boston prompted by an outbreak of COVID-19 cases among shelter residents.
This study describes demographic characteristics and hospital bed capacities of the 5 New York City boroughs, and evaluates whether differences in testing for coronavirus disease 2019 (COVID-19), hospitalizations, and deaths have emerged as a signal of racial, ethnic, and financial disparities.
This case series characterizes the demographics, health services use, and vital status and discharge dispositions of patients with polymerase chain reaction–confirmed coronavirus disease 2019 (COVID-19) hospitalized in the Kaiser Permanente Northern California health system in March 2020.
This case report describes a pregnant woman with symptomatic coronavirus disease who experienced a second-trimester miscarriage in association with documented placental SARS-CoV-2 infection.
This case series describes outcomes for 5 patients with VT storm refractory to drug therapy treated with left stellate ganglion transcutaneous magnetic stimulation (TCMS) to reduce cardiac sympathetic input.
In this Viewpoint, Donald Berwick summarizes the rapid changes the COVID-19 pandemic has wrought on the pace, scientific standards, delivery mechanisms, and working conditions of health care and how it has sharply increased awareness of the societal costs of poor public health preparedness and health inequities.
This Viewpoint reviews the revenue sources and financial liquidity of nonfederal US general hospitals to estimate the economic effects pandemic-related reductions in elective procedures and outpatient revenues might have, and argues for targeted government financial support for smaller, independent, and more rural institutions.
This Viewpoint discusses legal and privacy concerns raised by South Korea’s information technology (IT)–based containment of the COVID-19 pandemic and proposes use of aggregated rather than person-level data to protect the privacy of individuals while maintaining the effectiveness of public health measures.
This Viewpoint discusses ways the coronavirus pandemic is forcing change onto graduate medical education, including online implementation of preclerkship curricula and alternatives to in-person patient experiences in clinical clerkship rotations.
This Viewpoint discusses sources of anxiety revealed in conversations with health care workers (HCWs) in the early weeks of the coronavirus disease 2019 (COVID-19) pandemic, and the importance of expressions of gratitude from leadership for HCWs’ commitment and willingness to put themselves in harm’s way as a means to ameliorate that anxiety.
This Viewpoint discusses ways the coronavirus pandemic is threatening clinical trial conduct and enrollment, and suggests ways to adapt, including changes to how outcomes data are collected and how interventions are delivered and monitored, to minimize trial disruption, maximize trial benefit, and ensure patient health and safety during the pandemic.
This Viewpoint provides historical and legal context for governmental directives to close schools and businesses, ban public gatherings, impose curfews, issue stay-at-home orders, require quarantines for travelers, and impose travel restrictions during the COVID-19 pandemic, urging transparent evidence-based processes to ensure equity and social justice.
This Viewpoint examines the need to reconcile discrepancies between the definition of brain death in the 1981 Uniform Determination of Death Act and current diagnostic standards in the US given legal challenges arising from the differences.
This Viewpoint discusses ways in which artificial intelligence (AI) methods can enhance the use of health care data in detection, prognostication, and prediction; suggests ways in which AI tools might be better developed and deployed; and calls for increased focus on anticipated changes that will be made in the health care system to better benefit from the use of AI.
In this narrative medicine essay, a pediatrician confronts an impending neurofibromatosis type 1 diagnosis in her infant son and finds heroic parents of her patients who have profound medical challenges.
This JAMA Insights review explains the use of the effective reproduction number (Rt) as a measure of the number of secondary infectious disease cases spread from an initial case, and how this number is used to assess the effects of public containment and mitigation efforts to control SARS-CoV-2 transmission.
This Medical Letter provides a Table summarizing key information about drugs for depression published as part of a comprehensive review on the topic.
This Medical News feature discusses the use of convalescent plasma against COVID-19.
In this Medical News article, Howard Markel, MD, PhD, director of the Center for the History of Medicine at the University of Michigan, speaks about nonpharmaceutical interventions during the 1918-1919 influenza pandemic and their lessons for today.
This JAMA Patient Page explains the anatomy, causes, possible effects on fertility, and treatment of varicoceles, varicose veins in the testicle.
Create a personal account or sign in to: