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June 2020 - July 1883

Decade

Year

Issue

June 2, 2020, Vol 323, No. 21, Pages 2111-2210

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2020;323(21):e200023. doi:10.1001/jama.2020.0023
Original Investigation

Effect of a Patient-Centered Decision Support Tool on Rates of Trial of Labor After Previous Cesarean Delivery: The PROCEED Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA. 2020;323(21):2151-2159. doi:10.1001/jama.2020.5952

This randomized clinical trial compares the effect of a patient-centered decision support tool vs usual care on rates of trial of labor among women with a previous cesarean delivery.

Effect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial

Abstract Full Text
JAMA. 2020;323(21):2160-2169. doi:10.1001/jama.2020.6348

This randomized trial compares the effects of C-reactive protein (CRP)–guided antibiotic duration (discontinuation once CRP declined by 75% of peak value) vs fixed 7- vs 14-day durations on 30-day clinical failure rate among patients with gram-negative bacteremia.

Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients With Acute Ischemic Stroke

Abstract Full Text
has active quiz
JAMA. 2020;323(21):2170-2184. doi:10.1001/jama.2020.5697

This cohort study estimates associations between intravenous tissue plasminogen activator (tPA) door-to-needle times of less than 4.5 hours for acute ischemic stroke and 1-year mortality or readmission among Medicare beneficiaries aged 65 years or older.

Research Letter

Prevalence of SARS-CoV-2 Infection in Residents of a Large Homeless Shelter in Boston

Abstract Full Text
free access has active quiz
JAMA. 2020;323(21):2191-2192. doi:10.1001/jama.2020.6887

This study characterizes the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection detected on polymerase chain reaction (PCR) screening of a large homeless shelter population in Boston prompted by an outbreak of COVID-19 cases among shelter residents.

Variation in COVID-19 Hospitalizations and Deaths Across New York City Boroughs

Abstract Full Text
free access has multimedia
JAMA. 2020;323(21):2192-2195. doi:10.1001/jama.2020.7197

This study describes demographic characteristics and hospital bed capacities of the 5 New York City boroughs, and evaluates whether differences in testing for coronavirus disease 2019 (COVID-19), hospitalizations, and deaths have emerged as a signal of racial, ethnic, and financial disparities.

Characteristics of Hospitalized Adults With COVID-19 in an Integrated Health Care System in California

Abstract Full Text
free access
JAMA. 2020;323(21):2195-2198. doi:10.1001/jama.2020.7202

This case series characterizes the demographics, health services use, and vital status and discharge dispositions of patients with polymerase chain reaction–confirmed coronavirus disease 2019 (COVID-19) hospitalized in the Kaiser Permanente Northern California health system in March 2020.

Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection

Abstract Full Text
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JAMA. 2020;323(21):2198-2200. doi:10.1001/jama.2020.7233

This case report describes a pregnant woman with symptomatic coronavirus disease who experienced a second-trimester miscarriage in association with documented placental SARS-CoV-2 infection.

Case Series of Transcutaneous Magnetic Stimulation for Ventricular Tachycardia Storm

Abstract Full Text
JAMA. 2020;323(21):2200-2202. doi:10.1001/jama.2020.3833

This case series describes outcomes for 5 patients with VT storm refractory to drug therapy treated with left stellate ganglion transcutaneous magnetic stimulation (TCMS) to reduce cardiac sympathetic input.

Viewpoint

COVID-19: Beyond Tomorrow

Choices for the “New Normal”

Abstract Full Text
free access has active quiz has multimedia has audio
JAMA. 2020;323(21):2125-2126. doi:10.1001/jama.2020.6949

In this Viewpoint, Donald Berwick summarizes the rapid changes the COVID-19 pandemic has wrought on the pace, scientific standards, delivery mechanisms, and working conditions of health care and how it has sharply increased awareness of the societal costs of poor public health preparedness and health inequities.

COVID-19: Beyond Tomorrow

COVID-19 and the Financial Health of US Hospitals

Abstract Full Text
free access has active quiz
JAMA. 2020;323(21):2127-2128. doi:10.1001/jama.2020.6269

This Viewpoint reviews the revenue sources and financial liquidity of nonfederal US general hospitals to estimate the economic effects pandemic-related reductions in elective procedures and outpatient revenues might have, and argues for targeted government financial support for smaller, independent, and more rural institutions.

Information Technology–Based Tracing Strategy in Response to COVID-19 in South Korea—Privacy Controversies

Abstract Full Text
free access
JAMA. 2020;323(21):2129-2130. doi:10.1001/jama.2020.6602

This Viewpoint discusses legal and privacy concerns raised by South Korea’s information technology (IT)–based containment of the COVID-19 pandemic and proposes use of aggregated rather than person-level data to protect the privacy of individuals while maintaining the effectiveness of public health measures.

Medical Student Education in the Time of COVID-19

Abstract Full Text
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JAMA. 2020;323(21):2131-2132. doi:10.1001/jama.2020.5227

This Viewpoint discusses ways the coronavirus pandemic is forcing change onto graduate medical education, including online implementation of preclerkship curricula and alternatives to in-person patient experiences in clinical clerkship rotations.

Understanding and Addressing Sources of Anxiety Among Health Care Professionals During the COVID-19 Pandemic

Abstract Full Text
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JAMA. 2020;323(21):2133-2134. doi:10.1001/jama.2020.5893

This Viewpoint discusses sources of anxiety revealed in conversations with health care workers (HCWs) in the early weeks of the coronavirus disease 2019 (COVID-19) pandemic, and the importance of expressions of gratitude from leadership for HCWs’ commitment and willingness to put themselves in harm’s way as a means to ameliorate that anxiety.

Preserving Clinical Trial Integrity During the Coronavirus Pandemic

Abstract Full Text
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JAMA. 2020;323(21):2135-2136. doi:10.1001/jama.2020.4689

This Viewpoint discusses ways the coronavirus pandemic is threatening clinical trial conduct and enrollment, and suggests ways to adapt, including changes to how outcomes data are collected and how interventions are delivered and monitored, to minimize trial disruption, maximize trial benefit, and ensure patient health and safety during the pandemic.

Governmental Public Health Powers During the COVID-19 Pandemic: Stay-at-home Orders, Business Closures, and Travel Restrictions

Abstract Full Text
free access has active quiz has multimedia has audio
JAMA. 2020;323(21):2137-2138. doi:10.1001/jama.2020.5460

This Viewpoint provides historical and legal context for governmental directives to close schools and businesses, ban public gatherings, impose curfews, issue stay-at-home orders, require quarantines for travelers, and impose travel restrictions during the COVID-19 pandemic, urging transparent evidence-based processes to ensure equity and social justice.

Understanding Brain Death

Abstract Full Text
has audio
JAMA. 2020;323(21):2139-2140. doi:10.1001/jama.2020.3593

This Viewpoint examines the need to reconcile discrepancies between the definition of brain death in the 1981 Uniform Determination of Death Act and current diagnostic standards in the US given legal challenges arising from the differences.

Action-Informed Artificial Intelligence—Matching the Algorithm to the Problem

Abstract Full Text
JAMA. 2020;323(21):2141-2142. doi:10.1001/jama.2020.5035

This Viewpoint discusses ways in which artificial intelligence (AI) methods can enhance the use of health care data in detection, prognostication, and prediction; suggests ways in which AI tools might be better developed and deployed; and calls for increased focus on anticipated changes that will be made in the health care system to better benefit from the use of AI.

A Piece of My Mind

Securing the Sails

Abstract Full Text
JAMA. 2020;323(21):2143-2144. doi:10.1001/jama.2020.7164

In this narrative medicine essay, a pediatrician confronts an impending neurofibromatosis type 1 diagnosis in her infant son and finds heroic parents of her patients who have profound medical challenges.

Editorial

Can a Structured, Electronic Approach to Shared Decision-making Increase Attempted Trial of Labor?

Abstract Full Text
JAMA. 2020;323(21):2145-2146. doi:10.1001/jama.2020.5947

Patient and Study Participant Rights to Privacy in Journal Publication

Abstract Full Text
free access
JAMA. 2020;323(21):2147-2150. doi:10.1001/jama.2020.3590
JAMA Insights

Public Health Measures and the Reproduction Number of SARS-CoV-2

Abstract Full Text
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JAMA. 2020;323(21):2186-2187. doi:10.1001/jama.2020.7878

This JAMA Insights review explains the use of the effective reproduction number (Rt) as a measure of the number of secondary infectious disease cases spread from an initial case, and how this number is used to assess the effects of public containment and mitigation efforts to control SARS-CoV-2 transmission.

From The Medical Letter on Drugs and Therapeutics

Drugs for Depression

Abstract Full Text
has audio
JAMA. 2020;323(21):2188-2189. doi:10.1001/jama.2020.3040

This Medical Letter provides a Table summarizing key information about drugs for depression published as part of a comprehensive review on the topic.

Editor's Note

Long-term Outcomes After Thrombolytic Therapy for Acute Ischemic Stroke

Abstract Full Text
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JAMA. 2020;323(21):2184-2185. doi:10.1001/jama.2020.5269
Medical News & Perspectives

Testing an Old Therapy Against a New Disease: Convalescent Plasma for COVID-19

Abstract Full Text
has audio
JAMA. 2020;323(21):2114-2117. doi:10.1001/jama.2020.7456

This Medical News feature discusses the use of convalescent plasma against COVID-19.

Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Abstract Full Text
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JAMA. 2020;323(21):2118-2119. doi:10.1001/jama.2020.4165

In this Medical News article, Howard Markel, MD, PhD, director of the Center for the History of Medicine at the University of Michigan, speaks about nonpharmaceutical interventions during the 1918-1919 influenza pandemic and their lessons for today.

News From the Food and Drug Administration

Triple-Negative Breast Cancer Drug Receives Approval

Abstract Full Text
JAMA. 2020;323(21):2122. doi:10.1001/jama.2020.8312

e-Cigarette Hoodies and Backpacks Prompt FDA Warnings

Abstract Full Text
JAMA. 2020;323(21):2122. doi:10.1001/jama.2020.8313

Hemodialysis Device for Very Small Pediatric Patients

Abstract Full Text
JAMA. 2020;323(21):2122. doi:10.1001/jama.2020.8778
Bench to Bedside

Do Gut Bacteria Play a Role in Preeclampsia?

Abstract Full Text
JAMA. 2020;323(21):2120-2121. doi:10.1001/jama.2020.4755
Poetry and Medicine

I Remember Wells of Nausea Worse Than Pain

Abstract Full Text
JAMA. 2020;323(21):2206. doi:10.1001/jama.2020.1990
JAMA Revisited

Fact and Opinion on the Present Epidemic of Respiratory Disease

Abstract Full Text
JAMA. 2020;323(21):2207. doi:10.1001/jama.2020.6391
JAMA Patient Page

Varicoceles

Abstract Full Text
free access
JAMA. 2020;323(21):2210. doi:10.1001/jama.2020.0397

This JAMA Patient Page explains the anatomy, causes, possible effects on fertility, and treatment of varicoceles, varicose veins in the testicle.

Comment & Response

Surgery vs Endoscopy for Early Treatment of Chronic Pancreatitis

Abstract Full Text
JAMA. 2020;323(21):2202. doi:10.1001/jama.2020.4823

Surgery vs Endoscopy for Early Treatment of Chronic Pancreatitis—Reply

Abstract Full Text
JAMA. 2020;323(21):2203. doi:10.1001/jama.2020.4826

Vitamin C, Hydrocortisone, and Thiamine for Septic Shock

Abstract Full Text
JAMA. 2020;323(21):2203-2204. doi:10.1001/jama.2020.5844

Vitamin C, Hydrocortisone, and Thiamine for Septic Shock—In Reply

Abstract Full Text
JAMA. 2020;323(21):2204-2205. doi:10.1001/jama.2020.5850
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2020;323(21):2111-2112. doi:10.1001/jama.2019.13459
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