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June 2020 - July 1883

Decade

Year

Issue

June 9, 2020, Vol 323, No. 22, Pages 2231-2350

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2020;323(22):e200024. doi:10.1001/jama.2020.0024
Original Investigation

Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults

Abstract Full Text
JAMA. 2020;323(22):2268-2280. doi:10.1001/jama.2020.6918

This study used pooled cohort data to estimate the association between CT-assessed dysanapsis—a mismatch between airway tree caliber and lung size—and incident COPD in adults aged 60 years and older.

Association of Migraine With Aura and Other Risk Factors With Incident Cardiovascular Disease in Women

Abstract Full Text
has active quiz
JAMA. 2020;323(22):2281-2289. doi:10.1001/jama.2020.7172

This cohort study uses Women’s Health Study data to compare the association of migraine with aura vs other major vascular risk factors (diabetes, hypertension, dyslipidemia, smoking, BMI, CVD family history) with incidence of cardiovascular disease.

Accuracy of the PHQ-2 Alone and in Combination With the PHQ-9 for Screening to Detect Major Depression: Systematic Review and Meta-analysis

Abstract Full Text
JAMA. 2020;323(22):2290-2300. doi:10.1001/jama.2020.6504

This meta-analysis uses individual participant data from diagnostic accuracy studies to estimate the accuracy of the Patient Health Questionnaire–2 (PHQ-2) alone and combined with the PHQ-9 for detecting major depression.

Research Letter

Changes in SARS-CoV-2 Positivity Rate in Outpatients in Seattle and Washington State, March 1–April 16, 2020

Abstract Full Text
free access
JAMA. 2020;323(22):2334-2336. doi:10.1001/jama.2020.8097

This population epidemiology study characterizes trends in polymerase chain reaction (PCR) test positivity for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Washington State and the Seattle area between March 1 and April 16, 2020, before and after statewide physical distancing guidelines and stay-at-home orders.

Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure

Abstract Full Text
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JAMA. 2020;323(22):2336-2338. doi:10.1001/jama.2020.8255

This case series describes the proportion of awake, nonintubated inpatients with COVID-19 and hypoxemic respiratory failure requiring oxygen supplementation whose Pao2 increased ≥20% with prone positioning, and their respiratory status after resuming supine positioning.

Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit

Abstract Full Text
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JAMA. 2020;323(22):2338-2340. doi:10.1001/jama.2020.7861

This study measured respiratory parameters of 15 non-ICU patients before, during, and after receiving noninvasive ventilation in the prone position.

SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults

Abstract Full Text
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JAMA. 2020;323(22):2340-2341. doi:10.1001/jama.2020.8189

This cohort study compares rates of coronavirus PCR test positivity among Israelis with symptoms suspicious for COVID-19 who did and did not receive BCG vaccination as part of routine childhood immunization in the early 1980s.

Revisiting Leonardo da Vinci’s Vitruvian Man Using Contemporary Measurements

Abstract Full Text
JAMA. 2020;323(22):2342-2343. doi:10.1001/jama.2020.3501

This study uses 3D body scanner measurements of US Air Force recruits to compare ideal body proportions represented by Leonardo da Vinci’s Vitruvian Man with contemporary body proportions in young adult men and women.

US Preventive Services Task Force

Recommendation Statement

Screening for Unhealthy Drug Use: US Preventive Services Task Force Recommendation Statement

Abstract Full Text
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JAMA. 2020;323(22):2301-2309. doi:10.1001/jama.2020.8020

This 2020 US Preventive Services Task Force Recommendation Statement recommends screening for unhealthy drug use in adults 18 years or older when services for diagnosis, treatment, and care can be offered or referred (B recommendation) and concludes that evidence is insufficient to assess the balance of benefits and harms of screening for unhealthy drug use in adolescents (I statement).

Evidence Report

Screening for Unhealthy Drug Use: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Abstract Full Text
free access
JAMA. 2020;323(22):2310-2328. doi:10.1001/jama.2019.21381

This systematic review to support the 2020 US Preventive Services Task Force Recommendation Statement on screening for unhealthy drug use including nonmedical use of prescription drugs in adolescents and adults summarizes published evidence on the benefits and harms of primary care–based screening.

Viewpoint

COVID-19: Beyond Tomorrow

The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”)

Abstract Full Text
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JAMA. 2020;323(22):2241-2242. doi:10.1001/jama.2020.8102

This Viewpoint explains the ethical basis for implementing immunity-based licensing—certification of coronavirus immunity as a basis for permitting public activities—and anticipates challenges to effective implementing such a system, and potential solutions.

COVID-19: Beyond Tomorrow

Privileges and Immunity Certification During the COVID-19 Pandemic

Abstract Full Text
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JAMA. 2020;323(22):2243-2244. doi:10.1001/jama.2020.7712

This Viewpoint explains the ethics of implementing licensing or certification of coronavirus immunity as basis for permitting public activities, anticipates challenges to effectively implementing such a system, and proposes potential policy solutions.

COVID-19: Beyond Tomorrow

COVID-19 and Postinfection Immunity: Limited Evidence, Many Remaining Questions

Abstract Full Text
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JAMA. 2020;323(22):2245-2246. doi:10.1001/jama.2020.7869

This Viewpoint describes what is currently known about the immune response to coronavirus disease 2019 (COVID-19), highlights important gaps in knowledge, and identifies opportunities for future research.

COVID-19: Beyond Tomorrow

Reopening Society and the Need for Real-Time Assessment of COVID-19 at the Community Level

Abstract Full Text
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JAMA. 2020;323(22):2247-2248. doi:10.1001/jama.2020.7872

This Viewpoint discusses the need for population COVID-19 PCR and antibody surveys to better understand where communities are on the continuum of COVID-19 incidence and prevalence, to determine the effectiveness of mitigation strategies, and to plan for future mitigation strategies and development of vaccines and therapeutics.

Interpreting Diagnostic Tests for SARS-CoV-2

Abstract Full Text
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JAMA. 2020;323(22):2249-2251. doi:10.1001/jama.2020.8259

This Viewpoint discusses the 2 most common categories of testing to diagnose SARS-CoV-2—real-time PCR to identify viral RNA and serological diagnosis of IgG and IgM antibodies to assess immune response—and estimates time intervals for test positivity by specimen source to help clinicians interpret results relative to symptom onset.

Moving Personal Protective Equipment Into the Community: Face Shields and Containment of COVID-19

Abstract Full Text
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JAMA. 2020;323(22):2252-2253. doi:10.1001/jama.2020.7477

This Viewpoint discusses the prospect that face shields might be more effective than face masks at reducing community SARS-CoV-2 transmission and calls for rapid adoption of face shield-wearing by the public as an infection control strategy.

Surgery in a Time of Uncertainty: A Need for Universal Respiratory Precautions in the Operating Room

Abstract Full Text
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JAMA. 2020;323(22):2254-2255. doi:10.1001/jama.2020.7903

This Viewpoint proposes that universal respiratory precautions in the operating room—use of respirators with face masks and eye protection—could protect staff from possible coronavirus disease 2019 (COVID-19) infection and facilitate resumption of elective surgeries canceled during the first wave of the pandemic.

When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials?

Abstract Full Text
has audio
JAMA. 2020;323(22):2256-2257. doi:10.1001/jama.2020.3508

This Viewpoint discusses considerations that might lead physicians to change their practice based on RCTs reporting non–statistically significant differences in primary outcomes, including trial methodology, totality of evidence, cost, invasiveness, and labor-intensiveness of the interventions being compared.

Updated CDC Recommendations for Universal Hepatitis C Virus Screening Among Adults and Pregnant Women: Implications for Clinical Practice

Abstract Full Text
JAMA. 2020;323(22):2258-2259. doi:10.1001/jama.2020.3693

This Viewpoint discusses the clinical implications of the US Centers for Disease Control and Prevention’s (CDC’s) 2020 recommendation to screen all adults for hepatitis C virus (HCV) infection at least once and pregnant women during each pregnancy, including the need to offer substance use disorder referral and testing protocols for diagnosing perinatal HCV infection in newborns.

A Piece of My Mind

The Spectrum of Deaths Encountered by a Young Learner

Abstract Full Text
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JAMA. 2020;323(22):2260-2261. doi:10.1001/jama.2020.7083

In this narrative medicine essay, a medical student describes 3 patient deaths whose care she was involved in and expresses her hopes that what she learned will ground her professional course in compassion and patient care.

Editorial

Randomized Clinical Trials and COVID-19: Managing Expectations

Abstract Full Text
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JAMA. 2020;323(22):2262-2263. doi:10.1001/jama.2020.8115

Screening for Unhealthy Drug Use: Neither an Unreasonable Idea Nor an Evidence-Based Practice

Abstract Full Text
has audio
JAMA. 2020;323(22):2263-2265. doi:10.1001/jama.2019.20152

Is the Prone Position Helpful During Spontaneous Breathing in Patients With COVID-19?

Abstract Full Text
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JAMA. 2020;323(22):2265-2267. doi:10.1001/jama.2020.8539
JAMA Insights

Clinical Update

Management of COVID-19 Respiratory Distress

Abstract Full Text
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JAMA. 2020;323(22):2329-2330. doi:10.1001/jama.2020.6825

This JAMA Insights Clinical Update discusses the pathophysiology of SARS-CoV-2–related respiratory failure, distinguishing unique L and H phenotypes and their implications for ventilator strategies and settings.

JAMA Clinical Guidelines Synopsis

Initial Management of Acute Pancreatitis

Abstract Full Text
JAMA. 2020;323(22):2331-2332. doi:10.1001/jama.2020.2177

This JAMA Clinical Guidelines Synopsis summarizes the American Gastroenterological Association Institute’s 2018 guideline on initial management of acute pancreatitis.

Medical News & Perspectives

Global Effort to Collect Data on Ventilated Patients With COVID-19

Abstract Full Text
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JAMA. 2020;323(22):2233-2234. doi:10.1001/jama.2020.8341

This Medical News feature describes an international effort to compile data about ventilated patients with COVID-19.

Prioritizing Physician Mental Health as COVID-19 Marches On

Abstract Full Text
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JAMA. 2020;323(22):2235-2236. doi:10.1001/jama.2020.5205

This Medical News article is an interview with the University of New Mexico’s Eileen Barrett, MD, MPH, about the pandemic’s mental toll on health care workers—and how they and their employers can safeguard their emotional well-being.

The JAMA Forum

How Will COVID-19 Affect the Health Care Economy?

Abstract Full Text
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JAMA. 2020;323(22):2237-2238. doi:10.1001/jama.2020.7308
News From the Centers for Disease Control and Prevention

Spike in Poison Control Calls Related to Disinfectant Exposures

Abstract Full Text
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JAMA. 2020;323(22):2240. doi:10.1001/jama.2020.8307

Homeless Shelters Face High COVID-19 Risks

Abstract Full Text
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JAMA. 2020;323(22):2240. doi:10.1001/jama.2020.8854
Biotech Innovations

Existing Drugs Might Treat COVID-19

Abstract Full Text
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JAMA. 2020;323(22):2239. doi:10.1001/jama.2020.9265

Bionic Arm With Real-Time Sensation

Abstract Full Text
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JAMA. 2020;323(22):2239. doi:10.1001/jama.2020.8836

Blood Test Flags Multiple Cancers in Large Study

Abstract Full Text
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JAMA. 2020;323(22):2239. doi:10.1001/jama.2020.9266
The Arts and Medicine

Oedipus and the Coronavirus Pandemic

Abstract Full Text
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JAMA. 2020;323(22):2231-2232. doi:10.1001/jama.2020.8594

This Arts and Medicine feature draws lessons from Sophocles’ classic tragedies Oedipus Rex and Oedipus at Colonus about the limits of medicine and the importance of community in the midst of the coronavirus (COVID-19) pandemic.

Poetry and Medicine

The Phone Call

Abstract Full Text
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JAMA. 2020;323(22):2346. doi:10.1001/jama.2020.2098
JAMA Revisited

Immunization Against Plague: An Argument for Controlled Experiment

Abstract Full Text
free access
JAMA. 2020;323(22):2347. doi:10.1001/jama.2019.13488
JAMA Patient Page

Screening for Unhealthy Drug Use in Adults and Adolescents

Abstract Full Text
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JAMA. 2020;323(22):2350. doi:10.1001/jama.2020.8192

This JAMA Patient Page summarizes the US Preventive Services Task Force’s 2020 recommendations on screening for unhealthy drug use in adults and adolescents.

Comment & Response

Incisional Negative Pressure Wound Therapy After Surgery for Major Trauma–Related Fractures

Abstract Full Text
JAMA. 2020;323(22):2343-2344. doi:10.1001/jama.2020.5847

Incisional Negative Pressure Wound Therapy After Surgery for Major Trauma–Related Fractures—Reply

Abstract Full Text
JAMA. 2020;323(22):2344. doi:10.1001/jama.2020.5853

An Early Result Acceptance Program for Residency Application

Abstract Full Text
JAMA. 2020;323(22):2344-2345. doi:10.1001/jama.2020.6513

An Early Result Acceptance Program for Residency Application—Reply

Abstract Full Text
JAMA. 2020;323(22):2345. doi:10.1001/jama.2020.6516
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2020;323(22):2239. doi:10.1001/jama.2019.13470
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