This randomized clinical trial examines the effect of continuous glucose monitoring vs standard blood glucose monitoring on glycemic outcomes among adolescents and adults with type 1 diabetes and suboptimal glycemic control.
This randomized clinical trial compares the effect of continuous glucose monitoring vs standard blood glucose monitoring on percentage of time spent with hypoglycemia (glucose <70 mg/dL) among older adults with type 1 diabetes.
This randomized trial compares the effects of ticagrelor-based 12-month dual antiplatelet therapy (DAPT) vs 3-month DAPT switching to 9-month ticagrelor monotherapy on rates of major bleeding and cardiovascular events in patients with acute coronary syndromes (ACS) undergoing PCI with drug-eluting stent (DES) placement.
This case series describes subclinical development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in some patients and health care workers in a pediatric dialysis unit after contact with a seropositive patient.
This population epidemiology study investigates the prevalence of IgG and IgM antibodies to SARS-CoV-2 in Los Angeles County, California, as a marker of both active and past infections.
This study compares angiotensin-converting enzyme 2 (ACE2) gene expression, which has been associated with SARS-CoV-2 cell entry, in the nasal epithelium of children vs adults.
This cluster randomized clinical trial compares the effect of physician notification for colorectal cancer screening and cancer detection on patients who were in a patient-specific reminders group in which physicians received a list of nonadherent patients, in a generic reminders group in which physicians received general information about regional screening adherence, or in a usual care group in which physicians received no reminders.
This Viewpoint reviews the FDA’s May 2020 Emergency Use Authorization of the antiviral drug remdesivir for treatment of COVID-19 and discusses the need for a transparent distribution plan of a drug not otherwise available in the US and for which demand will likely exceed supply.
This Viewpoint proposes ethical principles to guide allocation of scarce inpatient therapies for hospitalized COVID-19 patients to maximize patient benefit, mitigate disparities, and minimize clinician burden.
This Viewpoint proposes implementing comparison groups for policy decisions, for example assessing disease transmission with alternative housing vs in-home isolation of individuals who test positive for coronavirus disease 2019 (COVID-19), or with different durations or cycles of school openings, to gather data that could make broader and future policy implementations more informed and effective.
This Viewpoint compares manual and digital strategies for coronavirus disease 2019 (COVID-19) contact tracing, describes how countries in Asia and Europe have used smartphone tracking, and discusses privacy and discrimination concerns and strategies for balancing public health and civil liberties in the US.
This Viewpoint emphasizes the need for efficient and accurate data collection, aggregation, and analysis at the national level to properly manage the coronavirus pandemic, and proposes responses to the legal, ethical, and financial barriers that have historically delayed development of a national HIT infrastructure.
This Viewpoint describes changes in reimbursement standards, patient privacy (HIPAA) regulations, and licensing requirements that have occurred around provision of telehealth in the US in response to the COVID-19 pandemic and highlights opportunities to further standardize regulations and facilitate use of telehealth after the pandemic.
This Viewpoint discusses the role academic health systems can play in response to public health deficiencies identified in the coronavirus disease 2019 (COVID-19) pandemic, including developing early warning systems to identify future outbreaks, addressing community mental health needs more broadly, and working to reduce structural health inequities.
This Viewpoint discusses the effects that adverse childhood experiences (ACEs) can have on long-term mental and physical health and reviews the potential benefits and harms of screening for ACEs in primary care settings.
This Viewpoint discusses inequities in broadband access and digital health literacy in the US, and proposes policies and actions to bring equity to patient-facing digital health tools, in the context of a 2020 final rule release giving patients more control of their health data from the US Office of the National Coordinator (ONC) for Health Information Technology’s Cures (HI-TEC) Act.
In this narrative medicine essay, an infectious disease fellow describes her discomfort treating patients behind masks and glass doors, laments the distance it creates, and hopes when the COVID-19 pandemic ends that face-to-face medicine resumes.
This JAMA Guide to Statistics and Methods reviews overlap weighting, a technique to reduce the influence of patients who are nearly always treated or never treated on propensity score estimates, when attempting to reduce bias associated with nonrandomized treatment in observational study populations.
This JAMA Insights Clinical Update reviews indications and timing of insulin therapy for management of type 2 diabetes, emphasizing the likely benefit of its use as first-line therapy in patients with HbA1c levels less than 9.0%.
A woman from the Southeastern US with a history of smoking, poorly controlled diabetes, and inhalational medical marijuana use had 4 months of productive cough, weight loss, subjective fevers, 3 days of worsening chest pain, and a large right upper lobe cavitary mass on chest CT unresponsive to antibiotics. AFB smear and GeneXpert MTB/RIF testing were negative; she developed a right-sided tension pneumothorax after intubation for hypoxemia, and chest tube placement yielded charcoal-colored pleural fluid. What is the diagnosis and what would you do next?
This Medical News feature discusses the role of contact tracing in containing coronavirus disease 2019.
This JAMA Patient Page describes spinal metastases, their diagnosis, and their treatment options.
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