Because intravenous (IV) iron can induce hypophosphatemia, the 2 clinical trials in this report directly compare the effects of 2 IV iron formulations, iron isomaltoside (now known as ferric derisomaltose) and ferric carboxymaltose, on phosphate levels in patients with iron-deficiency anemia unresponsive to oral iron.
This population epidemiology study uses Danish registry data to examine associations between neurological disorders and higher suicide rates from 1980 through 2016.
This meta-analysis of trials and observational studies evaluates the association of the use of home noninvasive positive pressure ventilation (NIPPV) via home mechanical ventilator (HMV) and bilevel positive airway pressure (BPAP) devices with clinical outcomes and adverse events in patients with chronic obstructive pulmonary disease (COPD) and hypercapnia.
This randomized clinical trial compares the effects of treatment with intravenous vitamin C, hydrocortisone, and thiamine compared with intravenous hydrocortisone alone on duration of time alive and free of vasopressor use over 7 days in patients with septic shock.
This population epidemiology study uses data from the National Youth Tobacco Survey to assess trends in self-reported use of marijuana in electronic cigarettes among US middle school and high school students from 2017 to 2018.
This national survey study uses Monitoring the Future data to characterize trends in the prevalence of marijuana vaping in 2017, 2018, and 2019 among 8th, 10th, and 12th graders.
This Viewpoint discusses the adverse effects on patients of low billing quality (such as extremes in billing practices, pricing, and collection tactics), and proposes a 5-item rating system benchmarking billing quality to reduce financial harms and barriers to care, and improve health care quality and patient outcomes.
In this Viewpoint, Raina Merchant uses the 2019 launch of Facebook’s Preventive Health tool, which makes preventive health recommendations based on user age and sex, to discuss the role of social media in influencing health behaviors, reaching vulnerable populations, and advancing public health.
This Viewpoint describes principles underlying early brain-computer interfaces (BCIs) designed to read electrical brain signals, analyze how brain activity patterns contribute to vocal tract movements, and reproduce the sound patterns as speech toward the goal of restoring paralyzed individuals’ natural rate of communication and quality of life.
This Viewpoint considers how physicians can help patients align health span with life span given trends toward increased longevity and emphasizes the importance of a sense of purpose, social engagement, and lifestyle choices to improve outcomes of morbidity, mortality, and quality of life.
In this narrative medicine essay, an Asian American hospital chaplain reviews the film The Farewell, which tells the story of a Chinese family taking elaborate measures to hide a cancer diagnosis from the family matriarch, and compares it to her own professional and personal experience.
This JAMA Guide to Statistics and Methods reviews how propensity score methods can be used with observational data to mimic comparison populations in a randomized trial and account for differences that might lead to biased conclusions.
This JAMA Clinical Guidelines Synopsis summarizes the Advisory Committee on Immunization Practices’ 2019 updated recommendations for human papillomavirus vaccination for adults.
This Medical Letter review summarizes drugs available for the treatment of bacterial conjunctivitis and dry eye disease, including detail on formulations, dosage, and cost.
This Medical News story examines the outcry over a recently published guideline that found insufficient evidence to recommend eating less red meat.
This JAMA Patient Page describes different possible causes of memory loss, including neurodegenerative dementias and other conditions that may be reversible or permanent.
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