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February 11, 2020, Vol 323, No. 6, Pages 491-580

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2020;323(6):e200008. doi:10.1001/jama.2020.0008
Original Investigation

Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound Dressing on Deep Surgical Site Infection After Surgery for Lower Limb Fractures Associated With Major Trauma: The WHIST Randomized Clinical Trial

Abstract Full Text
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JAMA. 2020;323(6):519-526. doi:10.1001/jama.2020.0059

This randomized clinical trial compares the effects of incisional negative pressure wound therapy vs standard wound dressing on deep surgical site infection (SSI) at 30 days among patients undergoing surgery for major trauma–related lower limb fractures.

Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial

Abstract Full Text
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JAMA. 2020;323(6):527-537. doi:10.1001/jama.2020.0103

This randomized trial compares the effect of combining standard antibiotic therapy (intravenous vancomycin or daptomycin) with an antistaphylococcal β-lactam (intravenous flucloxacillin, cloxacillin, or cefazolin) vs standard therapy alone on a composite outcome of mortality, bacteremia, relapse, or treatment failure in adults with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia.

Out-of-Network Bills for Privately Insured Patients Undergoing Elective Surgery With In-Network Primary Surgeons and Facilities

Abstract Full Text
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JAMA. 2020;323(6):538-547. doi:10.1001/jama.2019.21463

This study uses claims data from a large US health insurer to describe the proportion of times patients who had undergone elective surgery at in-network facilities with in-network primary surgeons received out-of-network bills between 2012 and 2017.

Research Letter

Estimates of Medication Diversion in Hospice

Abstract Full Text
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JAMA. 2020;323(6):566-568. doi:10.1001/jama.2019.20388

This study uses a random survey of US hospice agencies to estimate rates of confirmed and suspected cases of medication diversion away from patients in hospice and association of diversion rates with agency characteristics and state opioid death rates.

Reported Heroin Use, Use Disorder, and Injection Among Adults in the United States, 2002-2018

Abstract Full Text
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JAMA. 2020;323(6):568-571. doi:10.1001/jama.2019.20844

This study uses National Surveys on Drug Use and Health data to characterize trends in heroin use, heroin use disorder, and heroin injection overall and by age, race, and geographic region.

Viewpoint

Improving the Residency Application and Selection Process: An Optional Early Result Acceptance Program

Abstract Full Text
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JAMA. 2020;323(6):503-504. doi:10.1001/jama.2019.21212

This Viewpoint proposes an early result match program for applicants to postgraduate training programs, much like early decision programs at undergraduate colleges, as a means to address the rise in number of residency applications and to ensure better fit between trainees and programs.

Sharing Patient Data Without Exploiting Patients

Abstract Full Text
JAMA. 2020;323(6):505-506. doi:10.1001/jama.2019.22354

This Viewpoint uses the framework of exploitation, an unequal sharing of benefits and harms between parties in an agreement, to highlight the ethical risks inherent in data-sharing partnerships between health systems and for-profit technology companies and to explore potential strategies for addressing those risks.

Sharing Health Care Data With Digital Giants: Overcoming Obstacles and Reaping Benefits While Protecting Patients

Abstract Full Text
JAMA. 2020;323(6):507-508. doi:10.1001/jama.2019.21215

This Viewpoint proposes principles of security, transparency, and privacy to guide data-sharing agreements between clinical organizations and digital technology companies as both seek electronic health record (EHR) data to grow their business and improve health care delivery and outcomes.

Artificial Intelligence in Health Care: A Report From the National Academy of Medicine

Abstract Full Text
JAMA. 2020;323(6):509-510. doi:10.1001/jama.2019.21579

This Viewpoint summarizes the 2019 AI in Healthcare report from the National Academy of Medicine (NAM), which reviews best practices for AI development, adoption, and maintenance and urges prioritization of equity, inclusion, and human rights in AI health system implementation.

A Piece of My Mind

Such Promise

Abstract Full Text
JAMA. 2020;323(6):511-512. doi:10.1001/jama.2020.0252

In this narrative medicine essay, a general pediatrics resident recalls the doubt and fear surrounding her high school diagnosis of ideopathic bone marrow suppression syndrome, her slow journey to recovery, and her how her family and physicians who cared for her nurtured her ambition to become a pediatric oncologist.

Editorial

Incisional Negative Pressure Wound Therapy Following Surgical Repair of Lower Extremity Fractures

Abstract Full Text
JAMA. 2020;323(6):513-514. doi:10.1001/jama.2019.22531

Combination Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: Not Ready for Prime Time

Abstract Full Text
JAMA. 2020;323(6):515-516. doi:10.1001/jama.2019.21472

New Therapeutic Strategies for Asthma

Abstract Full Text
JAMA. 2020;323(6):517-518. doi:10.1001/jama.2019.19985
Review

Diagnosis and Treatment of Parkinson Disease: A Review

Abstract Full Text
has active quiz has audio
JAMA. 2020;323(6):548-560. doi:10.1001/jama.2019.22360

This narrative review summarizes the clinical manifestations of Parkinson disease, proposes an algorithm for diagnosing and classifying subtypes of the disease, and discusses pharmacologic and nonpharmacologic approaches for managing its most troublesome signs and symptoms including tremor, dyskinesias, gait disturbance, and cognitive impairment.

JAMA Insights

Clinical Update

Outpatient Management of Chronic Asthma in 2020

Abstract Full Text
JAMA. 2020;323(6):561-562. doi:10.1001/jama.2019.19986

This JAMA Insights Clinical Update reviews recent evidence favoring use of inhaled corticosteroids (ICS)in all patients with asthma, regardless of frequency, and summarizes the SMART (single maintenance and reliever therapy) treatment approach, which uses an inhaler combining ICS and formoterol for control and relief of symptoms, and differences between SMART and symptom-driven therapy.

Clinical Update

Management of Acute Asthma in Adults in 2020

Abstract Full Text
JAMA. 2020;323(6):563-564. doi:10.1001/jama.2019.19987

This JAMA Insights Clinical Update reviews management of asthma exacerbations, including the use of inhaled corticosteroids (ICS), azithromycin, magnesium sulfate, and nebulized bronchodilators vs metered-dose inhalers (MDIs), and discusses the potential future role of benralizumab and other biological therapies.

Editor's Note

Surprise Billing in Surgery—Time for Action

Abstract Full Text
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JAMA. 2020;323(6):547. doi:10.1001/jama.2019.21461
Medical News & Perspectives

Which Postmenopausal Women Should Use Testosterone for Low Sexual Desire?

Abstract Full Text
JAMA. 2020;323(6):493-495. doi:10.1001/jama.2019.22070

This Medical News article discusses new international recommendations for female testosterone therapy.

The JAMA Forum

Legal Solutions for Universal Health Coverage

Abstract Full Text
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JAMA. 2020;323(6):496-497. doi:10.1001/jama.2019.22235
News From the Centers for Disease Control and Prevention

Dangers of Driving While High

Abstract Full Text
JAMA. 2020;323(6):500. doi:10.1001/jama.2020.0073

Mercury Poisoning From Skin Cream

Abstract Full Text
JAMA. 2020;323(6):500. doi:10.1001/jama.2020.0292
Biotech Innovations

Investigational Hemophilia A Gene Therapy Shows Sustained Benefit

Abstract Full Text
JAMA. 2020;323(6):499. doi:10.1001/jama.2020.0470

Artificial Intelligence Improves Breast Cancer Screening in Study

Abstract Full Text
JAMA. 2020;323(6):499. doi:10.1001/jama.2020.0370

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Abstract Full Text
JAMA. 2020;323(6):499. doi:10.1001/jama.2020.0471
JAMA Infographic

US Statistics on Surprise Medical Billing

Abstract Full Text
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JAMA. 2020;323(6):498. doi:10.1001/jama.2020.0065
Poetry and Medicine

March 26

Abstract Full Text
JAMA. 2020;323(6):575. doi:10.1001/jama.2019.21454
JAMA Revisited

Art of Therapy

Abstract Full Text
JAMA. 2020;323(6):576. doi:10.1001/jama.2019.13301

A M A grams

Abstract Full Text
JAMA. 2020;323(6):576. doi:10.1001/jama.2019.22149
JAMA Patient Page

Medical Cannabis

Abstract Full Text
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JAMA. 2020;323(6):580. doi:10.1001/jama.2019.17403

This JAMA Patient Page describes use of preparations of the cannabis plant to treat medical conditions, the strength of evidence supporting such use, and the risks involved.

Comment & Response

Increasing Spending on Primary Care to Reduce Health Care Costs

Abstract Full Text
JAMA. 2020;323(6):571. doi:10.1001/jama.2019.20634

Increasing Spending on Primary Care to Reduce Health Care Costs—Reply

Abstract Full Text
JAMA. 2020;323(6):571-572. doi:10.1001/jama.2019.20637

Supply Chain Optimization and Waste Reduction

Abstract Full Text
JAMA. 2020;323(6):572-573. doi:10.1001/jama.2019.20854

Supply Chain Optimization and Waste Reduction—Reply

Abstract Full Text
JAMA. 2020;323(6):573. doi:10.1001/jama.2019.20860
Correction

Incorrect Information

Abstract Full Text
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JAMA. 2020;323(6):573. doi:10.1001/jama.2020.0097

Missing Figure Legend

Abstract Full Text
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JAMA. 2020;323(6):573. doi:10.1001/jama.2020.0138

Calculation Adjustment in Article on Waste and Savings in Health Care

Abstract Full Text
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JAMA. 2020;323(6):573. doi:10.1001/jama.2020.0228

Calculation Adjustment in Related Article

Abstract Full Text
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JAMA. 2020;323(6):573. doi:10.1001/jama.2020.0253
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2020;323(6):491-492. doi:10.1001/jama.2019.13294
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