This randomized clinical trial compares the effects of an out-of-hospital tranexamic acid bolus vs placebo within 2 hours of traumatic brain injury (TBI) on 6-month functional neurologic outcome (Glasgow Coma Scale-Extended score >4) in patients with moderate or severe TBI.
This study uses data from the Medicare Physician Compare database to assess associations between patient social risk, defined as dual eligibility for Medicare and Medicaid, and physicians’ Merit-based Incentive Payment System (MIPS) data scores, a proxy for patient outcomes and care value.
This study uses data from the Medicare Physician Compare database to assess associations between clinician affiliation with health systems and performance scores and value-based reimbursement under the 2019 Merit-based Incentive Payment System (MIPS).
This interim analysis of 2 randomized trials compares adverse reactions and neutralizing antibody responses to inactivated coronavirus disease 2019 (COVID-19) vs adjuvant-only control vaccination, and compares the outcomes at varying vaccine doses among healthy adults in China.
This study examined the sociodemographic and clinical characteristics of patients, as well as their clinical outcomes, during a surge in COVID-19 disease in Houston, Texas.
This study describes correlations between the dollar amount of relief funding authorized by the US Congress to fund prevention, diagnosis, and treatment of coronavirus disease 2019 (COVID-19) and to reimburse health care entities for lost revenues, and county-level Black population fraction accounting for county COVID-19 burden, comorbidity, and hospital financial health.
This study describes trends in the incidence of hepatocellular carcinoma within the Veterans Health Administration from 2002 to 2018 before and after widespread direct-acting anti–hepatitis C virus (HCV) treatment.
This Viewpoint from the FDA reviews the minimum safety and efficacy standards COVID-19 vaccine candidates would need to meet to be considered for approval, and affirms its commitments to evaluating both in diverse populations and to postmarketing surveillance as means to ensure that approval will meet the highest safety and regulatory standards based on science and evidence, not politics.
This Viewpoint provides examples of how applying precision public health operations can help curb the COVID-19 pandemic.
This Viewpoint discusses the prospects for exacerbation of the coronavirus disease 2019 (COVID-19) pandemic during hurricane season in the US, and proposes reinforcement of public health measures, clear communication, and learning from each experience to reduce the risks of hurricane-related harms and increases in COVID-19 cases.
This Viewpoint emphasizes the importance of precise language to help patients make evidence-informed decisions in shared decision-making, and argues that references to “chances of harms and benefits” will be more understandable to patients than discussions of “probabilities of risks and benefits.”
This Viewpoint reviews progress and challenges to date in federal and state efforts to transition combination oral contraceptives (COCs) from being prescription only to over-the-counter status in the US.
In this narrative medicine essay, a neurologist relates the story of her miscarriage while touring immigration detention centers in Texas documenting medical care and human rights violations and shares her deep sorrow for the women who lost children either by force or miscarriages while incarcerated.
This JAMA Insights Clinical Update reviews the diagnosis and management of polymyalgia rheumatica and giant cell arteritis and provides a suggested treatment algorithm for giant cell arteritis.
A 31-year-old woman with a history of childhood heart murmur has exercise intolerance due to dyspnea, no chest pain, a fixed split S2 and a 2/6 systolic murmur at the left upper sternal border, and incomplete right bundle-branch block on ECG. Chest imaging shows increased vascularity, cardiomegaly, and an enlarged right atrium and right ventricle. What is the diagnosis and what would you do next?
This Medical News feature examines what might happen when COVID-19 meets seasonal influenza this fall.
This Medical News article reports on efforts to increase flu vaccinations during the COVID-19 pandemic.
This Arts and Medicine feature describes the integration of local dance traditions into pulmonary rehabilitation programs for COPD and tuberculosis patients in low- and middle-income countries.
This JAMA Patient Page describes heart failure and its diagnosis, treatment options, and prevention measures.
This JAMA Patient Page reviews the symptoms and signs of COVID-19, at-home management of the infection, and precautions to take while caring for someone with it.
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