This randomized trial compares the effect of transcatheter pulmonary vein isolation during catheter ablation with vs without ethanol infusion into the vein of Marshall, an embryologic remnant of the left superior vena cava implicated in atrial fibrillation pathogenesis, on freedom from atrial arrhythmia at 12 months.
This randomized clinical trial compares the effect of regional citrate vs systemic heparin anticoagulation on dialysis filter life span and 90-day mortality among critically ill adults with acute kidney injury (AKI) receiving continuous kidney replacement therapy.
This cohort study compares net risk for ischemic vs hemorrhagic events at 12 months among patients treated with ticagrelor vs clopidogrel during and after percutaneous coronary intervention (PCI) management of acute coronary syndrome (ACS).
This study compares the numbers of nonfatal, unintentional opioid-related opioid overdoses presenting to a US urban emergency department during the early months of the coronavirus disease 2019 (COVID-19) pandemic (March-June 2020) vs 2019, overall and by age, race/ethnicity, and insurance status.
This substance use epidemiology study uses a commercial urine drug testing (UDT) service’s data to compare UDT results for cocaine, fentanyl, heroin, and methamphetamine before vs after US declaration of coronavirus disease 2019 (COVID-19) as a national emergency among patients diagnosed with or at risk of substance use disorders.
This study describes changes in blood donor demographics and seroreactivity after testing of blood donations for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies began and was publicized in the US in mid-June 2020.
This guideline from the International Antiviral (formerly AIDS) Society–USA updates practice recommendations for managing HIV infection including when to initiate antiviral therapy, how to monitor patients’ response, when to change antiviral regimens, and use of preexposure prophylaxis (PrEP) to prevent infection in those at risk.
This Viewpoint proposes that ethical principles of preventing harm, helping disadvantaged populations, and achieving equal treatment should guide COVID-19 vaccine distribution, supporting initial allocation to health care workers, people in high-risk occupations and housing, and those with high-risk medical conditions.
This Viewpoint proposes that varying combinations of evidence, physician influence, and economics guide the continuation or de-adoption of low-value health services and can help organize and prioritize policy initiatives to drive down the prevalence of wasteful care.
This Viewpoint uses findings from a June 2019 National Academies of Sciences, Engineering, and Medicine (NASEM) workshop report and subsequent data to summarize known environmental and health effects of extreme wildfires, emphasizing their differential adverse effects on low-income, non–English-speaking, and other vulnerable communities.
This Viewpoint describes 4 approaches for primary care clinicians to incorporate genetics care into their practices, and the systems-level interventions needed to operationalize them, including collecting a family history, initiating genomic testing and diagnostic workup, referral to genetics subspecialists, and monitoring disease surveillance.
This Viewpoint argues for inclusion of simply worded nutrition warnings on foods with excessive levels of sugar, sodium, and saturated fat, discussing international experience with the practice and its potential to incentivize healthier food products and reduce health inequities.
In this narrative medicine essay, a surgical oncologist describes the erosion of her confidence when patients and colleagues question her abilities or ignore her contributions based on her diminutive stature and sex and suggests that colleagues offer encouragement and praise to help stay further damage.
This JAMA Guide to Statistics and Methods explains worst-rank score methods, a nonparametric statistical technique that assigns worst-case outcomes for patients with missing data to account for missingness that may reflect an adverse change in patient status (informative rather than random missingness).
This Medical News article describes the use of telephone visits to deliver care during the pandemic.
This Arts and Medicine feature presents “Outer Space”, a neo-punk song written, played, and produced by a practicing neurogenetics psychiatrist to honor the brilliance of people with autism spectrum disorder and their families.
This JAMA Patient Page describes the use of the carotid artery stenting procedure to reduce the risk of stroke in patients with carotid artery atherosclerosis.
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