This randomized clinical trial compares the effects of maternal docosahexaenoic acid supplementation from childbirth through 36 weeks’ postmenstrual age vs placebo on bronchopulmonary dysplasia–free survival in breastfed infants born before 29 weeks of gestation.
This cohort study uses Danish registry data to estimate the association between a prescription for angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) in the 6 months prior to a coronavirus disease 2019 (COVID-19) diagnosis and mortality among all patients and those with hypertension.
This meta-analysis uses individual participant data from clinical trials to estimate associations between radial artery vs saphenous vein grafting techniques and cardiovascular outcomes at 10 years among patients undergoing coronary artery bypass grafting (CABG).
This study characterizes the prevalence of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among hospital staff of a Belgian tertiary care center tested over 1 week in April 2020, and risk factors for seropositivity.
This study describes hospital-based obstetric service losses in rural US counties between 2014 and 2018 overall and by county population and urban adjacency.
This Viewpoint discusses the potential role of neutralizing monoclonal antibodies (MAbs) as a treatment for coronavirus disease 2019 (COVID-19) and as a means of prevention in high-risk populations, and it also raises possible limitations of the approach that need to be disproven or addressed for the strategy to be effective.
This Viewpoint proposes a policy framework for reopening of US primary, middle, and high schools (kindergarten through 12th grade) in fall 2020, including ramping up community public health responses in the summer, symptom screening of students, and privileging return-to-school decisions for younger children and others at risk for education disparities.
This Viewpoint discusses the financial pressures placed on US state budgets from the likely growth of Medicaid rolls during the COVID-19 pandemic, and proposes financing and policy adjustments to assist states in providing lifeline health care to low-income individuals during the crisis.
This Viewpoint proposes that global budgets, or fixed payments for care of a population over a specific time, are well suited to address the financial instability wrought by the COVID-19 pandemic on rural hospitals, removing the link between volume and revenue and allowing them to adapt to community needs.
This Viewpoint acknowledges the urgent need for answers to coronavirus-related public health questions such as individuals’ risk for coronavirus disease 2019 (COVID-19) exposure and disease if workplaces, schools, and businesses reopen, and emphasizes the need to translate cross-disciplinary science into usable form for policy decision makers, risk analysts, and the public.
In the context of potential aerosol spread of SARS-CoV-2 infection, this Viewpoint argues for use of upper-room germicidal UV (GUV) fixtures as a means to disinfect circulating air and prevent spread of COVID-19 and other infections in health care settings.
This Viewpoint discusses vulnerabilities in the US drug supply chain given a shift in manufacturing of pharmaceutical ingredients to other countries and calls for a system to identify high-value medications, forecast supplies and shortages, and incentivize domestic production.
This Viewpoint summarizes recommendations from a 2020 National Academies of Sciences, Engineering, and Medicine (NASEM) committee report on ways to improve regulatory oversight of drugs in an era of global pharmaceutical research and development.
This Viewpoint discusses examples of how many private sector businesses have aligned their core missions with civil and human rights and sustainability reforms, and emphasizes the importance of engaging the sector in achieving public health goals and accelerating worldwide recovery from the COVID-19 pandemic.
In this narrative medicine essay, a palliative medicine physician reflects on what is gained and lost in the turn toward telemedicine during the COVID-19 pandemic from a cornerstone belief that the in-person encounter is an anchoring condition for the patient-physician relationship.
This JAMA Guide to Statistics and Methods reviews the use of prerandomization run-in periods to improve treatment adherence and reduce loss to follow-up, and explains how they should be interpreted.
This JAMA Insights Clinical Update discusses what is known about the epidemiology and effects of SARS-CoV-2 infection in pregnancy, and summarizes Centers for Disease Control and Prevention (CDC) and professional organization (AAP and ACOG) recommendations for care of pregnant women with COVID-19.
This Medical Letter review summarizes the dosing, administration, cost, and adverse effects use of peanut allergen powder-dnfp (Palforzia), an oral immunotherapy indicated to mitigate allergic reactions, including anaphylaxis, caused by accidental peanut exposure in patients with a confirmed peanut allergy.
This Medical News article discusses nursing homes’ ongoing challenges during the novel coronavirus pandemic.
This JAMA Patient Page describes the causes, diagnosis, and treatment options for anosmia and olfactory dysfunction.