This randomized trial compares the effect of nebulized magnesium vs placebo added to albuterol on hospitalization at 24 hours of children with acute asthma in respiratory distress after initial therapy in Canadian pediatric emergency departments (EDs).
This cohort study uses UK Biobank data to estimate the risk for primary hepatic carcinoma and cancer-related death by HFE variant status among community-dwelling individuals of European ancestry in England, Scotland, and Wales.
This study investigates associations between US state certificate of need laws, which regulate health system spending and expansion, and markers of surgical quality, including procedural volume and postoperative outcomes for Medicare beneficiaries.
This Viewpoint compares the COVID-19 per capita overall and excess mortality rates in the US vs that of 18 OECD countries and the timing of any increases in excess mortality between February and September 2020.
This study describes trends in emergency department visits for ingestions by children of small neodymium magnets between 2009 and 2019, before, during, and after a 2014 Consumer Product Safety Commission rule restricting their sales.
This 2020 US Preventive Services Task Force Recommendation Statement recommends offering or referring adults with CVD risk factors to behavioral counseling interventions to promote a healthy diet and physical activity (B recommendation).
This systematic review to support the 2020 US Preventive Services Task Force Recommendation Statement on behavioral counseling to promote healthy diet and physical activity for cardiovascular disease (CVD) prevention summarizes published evidence on the benefits and harms of behavioral counseling to promote healthy diet and physical activity for CVD prevention in adults with cardiovascular risk factors.
This Viewpoint considers how COVID-19 vaccines can be distributed strategically, ethically, and legally given conflicts between consensus public health recommendations to prioritize allocation to disadvantaged racial and ethnic minorities and laws discouraging explicit consideration of race in policy decisions.
This Viewpoint summarizes the principles guiding coronavirus disease 2019 (COVID-19) vaccine recommendations made by the Advisory Committee on Immunization Practices (ACIP), a nongovernment advisory standing committee that counsels the Centers for Disease Control and Prevention on US population vaccine use, emphasizing that any final recommendations await phase 3 safety and efficacy data from ongoing trials.
This Viewpoint offers provisional answers to common questions the public will have about approved COVID-19 vaccines, including what they can expect regarding its effectiveness and safety, trustworthiness of the approval process, and whether society can return to normal once sufficient numbers of people are immunized.
This Viewpoint discusses the importance of understanding how next-generation genomic sequencing is being implemented—for whom noninvasive prenatal testing, whole-exome and -genome sequencing for suspected genetic disorders, and tumor sequencing is being used and who is paying for it—as precondition for knowing how the technologies can best serve patients.
In this narrative medicine essay, an emergency medical physician describes the lasting physical symptoms of a mild case of COVID-19, the effects of the illness on his family and professional community, and the lessons he’s learned about caring for symptomatic patients with normal test results.
This JAMA Insights Clinical Update discusses herd immunity in the context of the COVID-19 pandemic and explains the herd immunity threshold as a function of transmissibility (R0), the role of an effective vaccine and vaccination program in sustaining herd immunity, and the risks of an infection-based herd immunity approach.
A woman who had immigrated from Guatemala 1 year prior developed headache, photophobia, vomiting, somnolence, and confusion but no focal neurologic deficits. Brain CT showed ventriculomegaly, hydrocephalus, and cerebral edema, while brain MRI showed a nonenhancing lesion obstructing the aqueduct of Sylvius that moved to the fourth ventricle with hydrocephalus resolution on repeat imaging 5 days later. What is the diagnosis and what would you do next?
This Medical News feature examines the problem of people refusing to be tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
This Medical News article discusses updates in the American Cancer Society’s cervical cancer screening guideline.
This JAMA Patient Page describes what herd immunity is, how it limits disease spread, and how it is achieved in a population either by vaccination or by infection and recovery from a disease.
This JAMA Patient Page reviews the 2020 US Preventive Services Task Force’s recommendation to offer behavioral counseling to promote healthy diet and physical activity to prevent cardiovascular disease in adults with CVD risk factors (B recommendation).
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