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July 2020 - July 1883

Decade

Year

Issue

July 21, 2020, Vol 324, No. 3, Pages 209-310

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2020;324(3):e200029. doi:10.1001/jama.2020.0029
Original Investigation

Effect of Levothyroxine on Left Ventricular Ejection Fraction in Patients With Subclinical Hypothyroidism and Acute Myocardial Infarction: A Randomized Clinical Trial

Abstract Full Text
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JAMA. 2020;324(3):249-258. doi:10.1001/jama.2020.9389

This randomized trial evaluates the effect of levothyroxine vs placebo on left ventricular ejection fraction (LVEF) in patients with acute myocardial infarction and subclinical hypothyroidism.

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

Abstract Full Text
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JAMA. 2020;324(3):259-269. doi:10.1001/jama.2020.10369

This case series describes the clinical and laboratory characteristics of children hospitalized in England from March to May 2020 who met criteria for pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PIMS-TS), and compares syndrome characteristics with historical cases of Kawasaki disease (KD), KD shock syndrome, and toxic shock syndrome (TSS).

Public Attitudes Regarding Hospitals and Physicians Encouraging Donations From Grateful Patients

Abstract Full Text
JAMA. 2020;324(3):270-278. doi:10.1001/jama.2020.9442

This survey study assesses US public attitudes about practices used by health care institutions to encourage philanthropic donations from grateful patients.

Research Letter

Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City

Abstract Full Text
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JAMA. 2020;324(3):294-296. doi:10.1001/jama.2020.10374

This case series describes clinical characteristics, treatment, and outcomes of 17 previously healthy SARS-CoV-2–infected children and adolescents with an inflammatory phenotype overlapping with but distinct from Kawasaki disease and toxic shock syndrome admitted to a New York City hospital in late April and early May 2020.

Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain

Abstract Full Text
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JAMA. 2020;324(3):296-299. doi:10.1001/jama.2020.10125

This cohort study estimates associations between mode of delivery (vaginal vs cesarean delivery) and maternal and neonatal birth outcomes among SARS-CoV-2–infected women giving birth in Spain.

Use of Risk Evaluation and Mitigation Strategies by the US Food and Drug Administration, 2008-2019

Abstract Full Text
JAMA. 2020;324(3):299-301. doi:10.1001/jama.2020.6611

This study uses publicly available FDA.gov data to characterize trends in the US Food and Drug Administration’s use of Risk Evaluation and Mitigation Strategy (REMS) programs between 2008 and 2019 and to describe the number and classes of medications included, the strategies deployed, and the risks the program was intended to mitigate.

Viewpoint

The Moral Determinants of Health

Abstract Full Text
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JAMA. 2020;324(3):225-226. doi:10.1001/jama.2020.11129

In this Viewpoint, Berwick emphasizes that moral commitment to others, expressed through working for universal health coverage, criminal justice, and housing policy reform, climate change intervention, and more, is necessary if society is to meaningfully address adverse social determinants of health and reduce health inequalities.

COVID-19 Pandemic, Unemployment, and Civil Unrest: Underlying Deep Racial and Socioeconomic Divides

Abstract Full Text
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JAMA. 2020;324(3):227-228. doi:10.1001/jama.2020.11132

This Viewpoint discusses the inequalities underlying the preferential spread of COVID-19 and of economic hardship in lower-income communities of color in the US, and sees the national protests in support of the Black Lives Matter movement as a natural consequence of those inequities and an opportunity to change the systems that create them.

Policy Solutions for Reversing the Color-blind Public Health Response to COVID-19 in the US

Abstract Full Text
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JAMA. 2020;324(3):229-230. doi:10.1001/jama.2020.10531

This Viewpoint reviews proposed legislation to address health disparities the COVID-19 pandemic has exposed and calls for reform and redesign of the US health care system and society to address inequities that affect persons of color and other vulnerable groups.

COVID-19: Beyond Tomorrow

Responding to the COVID-19 Pandemic: The Need for a Structurally Competent Health Care System

Abstract Full Text
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JAMA. 2020;324(3):231-232. doi:10.1001/jama.2020.9289

This Viewpoint highlights the structural drivers of disadvantage and poverty that are antecedents of health inequity in the COVID-19 pandemic and proposes proportionately structural changes to how health and medical education systems operate to advance the health of individuals, communities, and their surrounding environments.

COVID-19: Beyond Tomorrow

Health Care Policy After the COVID-19 Pandemic

Abstract Full Text
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JAMA. 2020;324(3):233-234. doi:10.1001/jama.2020.10777

This Viewpoint discusses the necessity and prospects for health care reform in the wake of the coronavirus disease 2019 (COVID-19) pandemic, reviewing policy options to fund universal coverage, incentivize efficiencies, and reduce political opposition to change.

Validation and Utility Testing of Clinical Prediction Models: Time to Change the Approach

Abstract Full Text
JAMA. 2020;324(3):235-236. doi:10.1001/jama.2020.1230

In this Viewpoint, John Ioannidis and colleagues discuss the proliferation of undervalidated or unvalidated clinical prediction models (CPMs) and propose an open-source repository where risk prediction scores could be updated in real time and validated as a means to facilitate identification of best-performing and reduce creation of duplicate or unhelpful models.

Alternative Payment Models—Victims of Their Own Success?

Abstract Full Text
JAMA. 2020;324(3):237-238. doi:10.1001/jama.2020.4133

This Viewpoint examines whether alternative payment models are a success according to the lack of significant findings by individual demonstration projects on the one hand and the plateau of overall health care spending as a share of the gross domestic product (GDP) on the other.

Can Infections Cause Alzheimer Disease?

Abstract Full Text
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JAMA. 2020;324(3):239-240. doi:10.1001/jama.2020.4085

This Viewpoint considers whether viral infection contributes to Alzheimer disease.

Identifying the Risks of Unproven Regenerative Medicine Therapies

Abstract Full Text
JAMA. 2020;324(3):241-242. doi:10.1001/jama.2020.9375

This Viewpoint discusses safety concerns surrounding unproven and unregulated regenerative medicine products—typically bone marrow, fat, placental, or umbilical cord stem cells proposed as therapies—and offers guidance about how to evaluate if the therapies meet basic Food and Drug Administration requirements for investigational agents.

A Piece of My Mind

Do No Harm

Abstract Full Text
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JAMA. 2020;324(3):243-244. doi:10.1001/jama.2020.11241

In this narrative medicine essay, a primary care physician finds little solace in his medical training while caring for his 2 young daughters as a stay-at-home dad.

Editorial

2020—A Year That Will Be Remembered

Abstract Full Text
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JAMA. 2020;324(3):245. doi:10.1001/jama.2020.11308

SARS-CoV-2–Related Inflammatory Multisystem Syndrome in Children: Different or Shared Etiology and Pathophysiology as Kawasaki Disease?

Abstract Full Text
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JAMA. 2020;324(3):246-248. doi:10.1001/jama.2020.10370
Review

Perioperative Cardiovascular Risk Assessment and Management for Noncardiac Surgery: A Review

Abstract Full Text
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JAMA. 2020;324(3):279-290. doi:10.1001/jama.2020.7840

This narrative review summarizes evidence that addresses commonly asked questions about cardiovascular risk assessment prior to noncardiac surgery, such as the role of preoperative stress testing and medication to reduce surgical risk and the need to discontinue anticoagulants.

JAMA Insights

Women's Health

Medications for Primary Prevention of Breast Cancer

Abstract Full Text
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JAMA. 2020;324(3):291-292. doi:10.1001/jama.2020.9246

This JAMA Insights Clinical Update reviews indications for use of medications for primary prevention of breast cancer and the comparative effectiveness and adverse effects of selective estrogen receptor modulators (tamoxifen, raloxifene) and aromatase inhibitors (anastrozole, exemestane) for this purpose.

Medical News & Perspectives

Latin America and Its Global Partners Toil to Procure Medical Supplies as COVID-19 Pushes the Region to Its Limit

Abstract Full Text
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JAMA. 2020;324(3):217-219. doi:10.1001/jama.2020.11182

This Medical News article discusses Latin America’s critical shortages of medical supplies including personal protective equipment and ventilators during the coronavirus disease 2019 pandemic.

Anthony Fauci, MD, on COVID-19 Vaccines, Schools, and Larry Kramer

Abstract Full Text
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JAMA. 2020;324(3):220-222. doi:10.1001/jama.2020.9222

In this Medical News article, Anthony Fauci, MD, the country’s top infectious diseases expert, discusses the latest on COVID-19 and memories of a friend from another pandemic.

News From the Food and Drug Administration

HIV Antiviral Expanded for Use in Very Young Children

Abstract Full Text
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JAMA. 2020;324(3):224. doi:10.1001/jama.2020.12060

Watch Your Medicine: Video Game Therapy for Children With ADHD

Abstract Full Text
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JAMA. 2020;324(3):224. doi:10.1001/jama.2020.11924

Second Drug Okayed for Rare Central Nervous System Disease

Abstract Full Text
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JAMA. 2020;324(3):224. doi:10.1001/jama.2020.12061
Global Health

Alarming Antimicrobial Resistance Trends Emerge Globally

Abstract Full Text
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JAMA. 2020;324(3):223. doi:10.1001/jama.2020.11330

Diverse HPV Strains Require Strategic Vaccine Use

Abstract Full Text
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JAMA. 2020;324(3):223. doi:10.1001/jama.2020.12058

Reducing Global Traffic Deaths With Seatbelts and Other Technology

Abstract Full Text
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JAMA. 2020;324(3):223. doi:10.1001/jama.2020.12059
Poetry and Medicine

Quarantine

Abstract Full Text
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JAMA. 2020;324(3):306. doi:10.1001/jama.2020.12008
JAMA Revisited

Current Comment

Abstract Full Text
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JAMA. 2020;324(3):307. doi:10.1001/jama.2019.13532
JAMA Patient Page

Breast Cancer Risk–Reducing Medications

Abstract Full Text
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JAMA. 2020;324(3):310. doi:10.1001/jama.2020.11784

This JAMA Patient Page describes the indications for use of medications to reduce breast cancer risk and the benefits and risks of the 2 major drug classes, SERMs (tamoxifen, raloxifene) and aromatase inhibitors (anastrozole, exemestane).

Comment & Response

PTSD Treatments for Veterans

Abstract Full Text
JAMA. 2020;324(3):301. doi:10.1001/jama.2020.7548

PTSD Treatments for Veterans—Reply

Abstract Full Text
JAMA. 2020;324(3):301-302. doi:10.1001/jama.2020.7554

Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump for Cardiogenic Shock

Abstract Full Text
JAMA. 2020;324(3):302-303. doi:10.1001/jama.2020.7557

Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump for Cardiogenic Shock

Abstract Full Text
JAMA. 2020;324(3):303. doi:10.1001/jama.2020.7551

Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump for Cardiogenic Shock—Reply

Abstract Full Text
JAMA. 2020;324(3):303-304. doi:10.1001/jama.2020.7560

Calculation Error in Study of Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain

Abstract Full Text
JAMA. 2020;324(3):304-305. doi:10.1001/jama.2020.12267
Correction

Errors in Data and Statistical Significance

Abstract Full Text
free access
JAMA. 2020;324(3):305. doi:10.1001/jama.2020.12271
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2020;324(3):209-210. doi:10.1001/jama.2019.13525
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