[Skip to Navigation]
Sign In

September 2021 - July 1883

Decade

Year

Issue

May 25, 2021, Vol 325, No. 20, Pages 2031-2126

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2021;325(20):e2017953. doi:10.1001/jama.2020.17953
Original Investigation

Effect of Continuous Infusion of Hypertonic Saline vs Standard Care on 6-Month Neurological Outcomes in Patients With Traumatic Brain Injury: The COBI Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA. 2021;325(20):2056-2066. doi:10.1001/jama.2021.5561

This clinical trial conducted in France explores whether continuous infusion of hypertonic saline solution improves neurological outcome at 6 months in patients with traumatic brain injury.

α2-Adrenergic Agonists or Stimulants for Preschool-Age Children With Attention-Deficit/Hyperactivity Disorder

Abstract Full Text
JAMA. 2021;325(20):2067-2075. doi:10.1001/jama.2021.6118

This retrospective review uses data from health records of preschool-age children with attention-deficit/hyperactivity disorder (ADHD) treated in developmental-behavioral pediatric practices to examine the improvements and adverse effects associated with the use of α2-adrenergic agonists vs stimulants for initial ADHD medication treatment.

Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes

Abstract Full Text
free access has active quiz
JAMA. 2021;325(20):2076-2086. doi:10.1001/jama.2021.5775

This cohort study uses Swedish national registry data to investigate associations between maternal SARS-CoV-2 test positivity in pregnancy and neonatal outcomes, including mortality and need for resuscitation, between March 2020 and January 2021.

Research Letter

S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021

Abstract Full Text
free access has active quiz
JAMA. 2021;325(20):2115-2116. doi:10.1001/jama.2021.5607

This study determined the spread of the B.1.1.7 SARs-CoV-2 variant in the Greater Toronto Area over 4 months by tracking S-gene target failure as marker.

Preliminary Investigation of In situ Thrombus Within Patent Foramen Ovale in Patients With and Without Stroke

Abstract Full Text
JAMA. 2021;325(20):2116-2118. doi:10.1001/jama.2021.4359

This study uses high-resolution optical coherence tomography to investigate whether patent foramen ovale could be the site of thrombus formation in patients with or without stroke.

US Preventive Services Task Force

Recommendation Statement

Behavioral Counseling Interventions for Healthy Weight and Weight Gain in Pregnancy: US Preventive Services Task Force Recommendation Statement

Abstract Full Text
free access has active quiz has audio
JAMA. 2021;325(20):2087-2093. doi:10.1001/jama.2021.6949

This 2021 Recommendation Statement from the US Preventive Services Task Force recommends that clinicians offer pregnant persons effective behavioral counseling interventions aimed at promoting healthy weight gain and preventing excess gestational weight gain in pregnancy (B recommendation).

Evidence Report

Counseling and Behavioral Interventions for Healthy Weight and Weight Gain in Pregnancy: Evidence Report and Systematic Review for the US Preventive Services Task Force

Abstract Full Text
free access has audio
JAMA. 2021;325(20):2094-2109. doi:10.1001/jama.2021.4230

This systematic review to support the 2021 US Preventive Services Task Force Recommendation Statement on interventions for healthy weight and weight gain in pregnancy summarizes published evidence on the benefits and harms of counseling and behavioral interventions for healthy weight and gestational weight gain in adolescent and adult women who are pregnant or planning a pregnancy.

Viewpoint

Precision Medicine for COVID-19: Phenotype Anarchy or Promise Realized?

Abstract Full Text
free access has active quiz
JAMA. 2021;325(20):2041-2042. doi:10.1001/jama.2021.5248

This Viewpoint discusses the trend toward identifying “subtypes” of various diseases (eg, asthma and COPD) and proposes criteria for justifying subclassifications of COVID-19, including biological plausibility, prompt identifiability, nonoverlap in cases, reproducibility, and treatment responsiveness

Designing a Successful Primary Care Physician Capitation Model

Abstract Full Text
JAMA. 2021;325(20):2043-2044. doi:10.1001/jama.2021.5133

This Viewpoint proposes 7 elements necessary for a successful transition from a fee-for-service (FFS) to a capitated payment model for primary care physicians, all intended to sustain their ability to improve the quality and value of the care they provide while reducing costs.

High and Rising Working-Age Mortality in the US: A Report From the National Academies of Sciences, Engineering, and Medicine

Abstract Full Text
JAMA. 2021;325(20):2045-2046. doi:10.1001/jama.2021.4073

This Viewpoint summarizes a 2021 report from the National Academies of Sciences, Engineering, and Medicine (NASEM) that details declining life expectancy among working-age adults in the US from drug and alcohol use, suicide, and cardiometabolic diseases, mortality disparities by race/ethnicity, socioeconomic status, and geography, and implications for health policy.

A Piece of My Mind

Defense Against Numbness

Abstract Full Text
free access
JAMA. 2021;325(20):2047-2048. doi:10.1001/jama.2021.7137

In this narrative medicine essay, an Asian American physician discusses how her race has played a role in interactions with patients, both negatively and positively, and how these exchanges have provided a lens through which to see mutual recognition and shared experience.

Editorial

Comparison of Medication Treatments for Preschool Children With ADHD: A First Step Toward Addressing a Critical Gap

Abstract Full Text
JAMA. 2021;325(20):2049-2050. doi:10.1001/jama.2021.5603

Understanding Risk for Newborns Born to SARS-CoV-2–Positive Mothers

Abstract Full Text
free access has active quiz
JAMA. 2021;325(20):2051-2052. doi:10.1001/jama.2021.6210

Behavioral Counseling Interventions for Healthy Weight During Pregnancy: An Ambitious Endeavor

Abstract Full Text
JAMA. 2021;325(20):2053-2055. doi:10.1001/jama.2021.5720
JAMA Guide to Statistics and Methods

Adjusting for Nonadherence or Stopping Treatments in Randomized Clinical Trials

Abstract Full Text
JAMA. 2021;325(20):2110-2111. doi:10.1001/jama.2021.2433

This JAMA Guide to Statistics and Methods describes various methods to handle trial participant nonadherence to study interventions.

JAMA Insights

Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission

Abstract Full Text
free access has active quiz
JAMA. 2021;325(20):2112-2113. doi:10.1001/jama.2021.5053

This JAMA Insights review summarizes basic measures of indoor air ventilation as a means to explain how increases in frequency of air exchange and filtration capture efficiency could mitigate far-field airborne transmission of SARS-CoV-2 inside rooms and buildings.

Medical News & Perspectives

Researchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants

Abstract Full Text
free access has active quiz has multimedia has audio
JAMA. 2021;325(20):2033-2035. doi:10.1001/jama.2021.7212

This Medical News article discusses clinical care and isolation for patients with prolonged SARS-CoV-2 infections, who researchers say may generate and transmit viral variants.

An Inside Look at a Post–COVID-19 Clinic

Abstract Full Text
free access has active quiz has audio
JAMA. 2021;325(20):2036-2037. doi:10.1001/jama.2021.2426

In this Medical News article, Aluko Hope, MD, former co-director of the Montefiore-Einstein Department of Medicine’s COVID-19 Recovery Clinic, discusses how the clinic helps patients with persistent symptoms of the disease.

News From the Centers for Disease Control and Prevention

Massive Costs of the US Opioid Epidemic in Lives and Dollars

Abstract Full Text
JAMA. 2021;325(20):2040. doi:10.1001/jama.2021.7464

Sexually Transmitted Disease Cases Continue to Break Records

Abstract Full Text
JAMA. 2021;325(20):2040. doi:10.1001/jama.2021.6937
Clinical Trials Update

Clear Surgical Masks Create More Positive Interactions With Patients

Abstract Full Text
JAMA. 2021;325(20):2039. doi:10.1001/jama.2021.6793

Upadacitinib Noninferior to Adalimumab for Psoriatic Arthritis

Abstract Full Text
JAMA. 2021;325(20):2039. doi:10.1001/jama.2021.7716

Patients Favor Surgical Repair of Ruptured ACL

Abstract Full Text
JAMA. 2021;325(20):2039. doi:10.1001/jama.2021.7718

Shorter Antibiotic Therapy Safe for Inpatients With Pneumonia

Abstract Full Text
JAMA. 2021;325(20):2039. doi:10.1001/jama.2021.7721

Patient Navigation Reduces Substance Abuse Disorder Readmissions

Abstract Full Text
JAMA. 2021;325(20):2039. doi:10.1001/jama.2021.7723
Health Agencies Update

Allergic Reactions to mRNA Vaccines

Abstract Full Text
free access
JAMA. 2021;325(20):2038. doi:10.1001/jama.2021.6941

Improving Maternal Health

Abstract Full Text
JAMA. 2021;325(20):2038. doi:10.1001/jama.2021.7584

Free, At-Home Rapid SARS-CoV-2 Tests

Abstract Full Text
free access has active quiz
JAMA. 2021;325(20):2038. doi:10.1001/jama.2021.7585
Poetry and Medicine

Oxheart

Abstract Full Text
JAMA. 2021;325(20):2121. doi:10.1001/jama.2021.5228
JAMA Revisited

The Social Responsibilities of Modern Medicine

Abstract Full Text
JAMA. 2021;325(20):2122. doi:10.1001/jama.2020.17954
JAMA Patient Page

Behavioral Interventions for Healthy Weight Gain During Pregnancy

Abstract Full Text
free access has audio
JAMA. 2021;325(20):2126. doi:10.1001/jama.2021.7530

This JAMA Patient Page summarizes the US Preventive Services Task Force’s 2021 recommendations on behavioral interventions for healthy weight gain during pregnancy.

Comment & Response

Effect of Sodium Nitrite on Survival of Cardiac Arrest to Hospital Admission

Abstract Full Text
JAMA. 2021;325(20):2118. doi:10.1001/jama.2021.4064

Effect of Sodium Nitrite on Survival of Cardiac Arrest to Hospital Admission—Reply

Abstract Full Text
JAMA. 2021;325(20):2118-2119. doi:10.1001/jama.2021.4067

US Hospital Data About Neonatal Abstinence Syndrome and Maternal Opioid-Related Diagnoses

Abstract Full Text
JAMA. 2021;325(20):2119-2120. doi:10.1001/jama.2021.4510

US Hospital Data About Neonatal Abstinence Syndrome and Maternal Opioid-Related Diagnoses—Reply

Abstract Full Text
JAMA. 2021;325(20):2120. doi:10.1001/jama.2021.4519
Correction

Addition of Nonauthor Collaborator Names of the COVID-19 Lombardy ICU Network

Abstract Full Text
free access
JAMA. 2021;325(20):2120. doi:10.1001/jama.2021.5060
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2021;325(20):2031-2032. doi:10.1001/jama.2020.17951
×