This randomized clinical trial assesses the effect of intravenous eptinezumab vs placebo on times to headache pain freedom and absence of most bothersome symptom (nausea, photophobia, or phonophobia) among patients experiencing a moderate to severe migraine attack.
This systematic review and meta-analysis assesses the benefits and harms associated with acute treatments for episodic migraine, including pharmacologic and nonpharmacologic therapies, with a focus on pain-related outcomes, function, and adverse events.
This study assesses the immunogenicity of the current COVID-19 mRNA vaccines in pregnant and lactating women against both the original SARS-CoV-2 USA-WA1/2020 strain as well as against the B.1.1.7 and B.1.351 variants of concern.
This online survey study of US adults characterizes trends in coronavirus vaccine hesitancy and public trust in vaccination before and after COVID-19 vaccine availability in the US.
This pharmacoepidemiology study uses insurance claims data to compare generic substitutions for drugs with vs without manufacturer copayment coupons in California vs surrounding states in the year before and after a January 2018 California ban on coupons intended to incentivize use of more expensive brand-name medication.
This Viewpoint discusses the importance of equitable international collaboration, innovative manufacturing and supply chain development, and shared governance to provide the billions of COVID-19 vaccine doses to the world’s low-income and low-resource populations that will be necessary to control the coronavirus pandemic.
This Viewpoint discusses the prospect that suicide prevention interventions at a population level could complement gains from individual-level approaches and help reverse the high toll of suicide in the US.
This Viewpoint describes the connections between the US opioid use disorder (OUD) epidemic and crises in health care workforce well-being and describes a collaboration between the National Academy of Medicine (NAM) and Federation of State Medical Boards (FSMB) to address both and harmonize regulatory standards and practices where possible.
This Viewpoint discusses the origins of the term provider as a reference to health care professionals, considers unintentional and potentially detrimental consequences of its use, and recommends replacement of the term with precise and respectful language that specifies the titles, roles, and responsibilities of people interacting with patients in health care settings.
In this narrative medicine essay, a neonatologist considers the differences in available COVID-19 resources between her native country India and her new home country the United States and describes her helpless feelings in aiding her family and friends in India.
This narrative review summarizes the evaluation and management of chronic pelvic pain using recommendations from consensus guidelines to facilitate clinical evaluation, treatment, improved care, and more positive patient-clinician interactions.
This JAMA Insights narrative review discusses the relationship of thyroid autoantibodies to autoimmune thyroid disease and emphasizes the importance of age, fertility, and pregnancy when interpreting thyroid function test results.
This Medical Letter provides 2 Tables summarizing key information about drugs for menopausal symptoms published as part of a comprehensive review on the topic.
This Medical News feature examines racial and ethnic disparities in the diagnosis and treatment of cystic fibrosis.
This Medical News article describes research showing that few clinicians are using a Medicare benefit launched in 2016 to reimburse for discussing advance care planning with patients.
This JAMA Patient Page describes the symptoms and complications of and the diagnosis and treatment options for gallstones in pregnant people.