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January 2023 - July 1883

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Issue

September 28, 2021, Vol 326, No. 12, Pages 1133-1222

In This Issue of JAMA

Audio Highlights

Abstract Full Text
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JAMA. 2021;326(12):e2018145. doi:10.1001/jama.2020.18145
Original Investigation

Effect of Thrombectomy With Combined Contact Aspiration and Stent Retriever vs Stent Retriever Alone on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel Occlusion: The ASTER2 Randomized Clinical Trial

Abstract Full Text
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JAMA. 2021;326(12):1158-1169. doi:10.1001/jama.2021.13827

This randomized clinical trial compares the effect of thrombectomy with contact aspiration and stent retriever combined vs stent retriever alone on revascularization in patients with acute ischemic stroke and large vessel occlusion.

Association of Labor Epidural Analgesia With Autism Spectrum Disorder in Children

Abstract Full Text
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JAMA. 2021;326(12):1170-1177. doi:10.1001/jama.2021.12655

This nationwide retrospective cohort study among children in Denmark assesses whether maternal exposure to epidural analgesia during labor is associated with incidence of autism spectrum disorder in offspring.

Association of Epidural Analgesia During Labor and Delivery With Autism Spectrum Disorder in Offspring

Abstract Full Text
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JAMA. 2021;326(12):1178-1185. doi:10.1001/jama.2021.14986

This cohort study assesses the association of maternal use of epidural analgesia during labor and delivery with autism spectrum disorder in offspring using a large population-based data set of term singleton children born in British Columbia, Canada, between April 1, 2000, and December 31, 2014.

Research Letter

Myocarditis and Pericarditis After Vaccination for COVID-19

Abstract Full Text
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JAMA. 2021;326(12):1210-1212. doi:10.1001/jama.2021.13443

This study investigates the incidence of myocarditis and pericarditis emergency department or inpatient hospital encounters before COVID-19 vaccine availability (January 2019–January 2021) and during a COVID-19 vaccination period (February-May 2021) in a large US health care system.

US Preventive Services Task Force

Recommendation Statement

Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive Services Task Force Recommendation Statement

Abstract Full Text
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JAMA. 2021;326(12):1186-1191. doi:10.1001/jama.2021.14781

This 2021 Recommendation Statement from the US Preventive Services Task Force recommends the use of low-dose aspirin (81 mg/d) as preventive medication for preeclampsia after 12 weeks of gestation in persons at high risk for preeclampsia (B recommendation).

Evidence Report

Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Abstract Full Text
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JAMA. 2021;326(12):1192-1206. doi:10.1001/jama.2021.8551

This systematic review to support the 2021 US Preventive Services Task Force Recommendation Statement on aspirin use to prevent preeclampsia and related morbidity and mortality summarizes published evidence on the benefits and harms of aspirin use in individuals at increased preeclampsia risk based on clinical risk factors or measurements associated with higher disease incidence.

Viewpoint

COVID-19 in Canada: Experience and Response to Waves 2 and 3

Abstract Full Text
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JAMA. 2021;326(12):1145-1146. doi:10.1001/jama.2021.14797

This Viewpoint describes the Canadian experience and response to the larger second and third waves of COVID-19 infections.

World Trade Center Health Program, 2012-2020: Implications for Clinicians and Health Care Systems

Abstract Full Text
JAMA. 2021;326(12):1147-1148. doi:10.1001/jama.2021.15739

This Viewpoint reviews the World Trade Center Health Program, established in 2011 to fund health care for responders and survivors of the 9/11 attacks in the US, including covered conditions and changing factors such as an aging member population.

Governing Human Germline Editing Through Patent Law

Abstract Full Text
JAMA. 2021;326(12):1149-1150. doi:10.1001/jama.2021.13824

This Viewpoint discusses ethical considerations and use of patents for human germline editing in the context of a recent World Health Organization report and release of several auxiliary documents exploring international governance tools for human genome engineering.

A Piece of My Mind

Shots in Arms

Abstract Full Text
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JAMA. 2021;326(12):1151-1152. doi:10.1001/jama.2021.15671

In this narrative medicine essay, a psychiatrist describes her volunteer role during the COVID-19 pandemic—administering vaccinations in a high school cafeteria.

Editorial

Low-Dose Aspirin for the Prevention of Preeclampsia

Abstract Full Text
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JAMA. 2021;326(12):1153-1155. doi:10.1001/jama.2021.14646

Labor Epidural Analgesia and Autism Spectrum Disorder: Is There an Association?

Abstract Full Text
JAMA. 2021;326(12):1155-1157. doi:10.1001/jama.2021.15369
JAMA Performance Improvement

Safety Culture as a Patient Safety Practice for Alarm Fatigue

Abstract Full Text
JAMA. 2021;326(12):1207-1208. doi:10.1001/jama.2021.8316

This JAMA Performance Improvement article summarizes the AHRQ guideline on alarm fatigue in its health care safety series, including factors important to successfully implement approaches to reduce false alarms, total alarms, and noise levels.

Medical News & Perspectives

Why Farmworkers Need More Than New Laws for Protection From Heat-Related Illness

Abstract Full Text
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JAMA. 2021;326(12):1135-1137. doi:10.1001/jama.2021.15454

This Medical News article discusses farmworkers’ heat-related health risks and efforts to establish a national standard to help protect them from dangerous working conditions.

News From the Centers for Disease Control and Prevention

Shifting Trends in West Nile and Other Arboviral Diseases

Abstract Full Text
JAMA. 2021;326(12):1140. doi:10.1001/jama.2021.15826

Salmonella Outbreak Is Linked to Restaurant Rather Than Food

Abstract Full Text
JAMA. 2021;326(12):1140. doi:10.1001/jama.2021.15219
Clinical Trials Update

Early Rehabilitation Leads to Better Function in Heart Failure

Abstract Full Text
JAMA. 2021;326(12):1139. doi:10.1001/jama.2021.15004

Pain Management Video Reduces Opioid Use After Cesarean Delivery

Abstract Full Text
JAMA. 2021;326(12):1139. doi:10.1001/jama.2021.15934

Remote Monitoring Reduced Symptoms Among Patients With Cancer

Abstract Full Text
JAMA. 2021;326(12):1139. doi:10.1001/jama.2021.15935

Closed-Loop Insulin Delivery for Outpatients With Type 2 Diabetes

Abstract Full Text
JAMA. 2021;326(12):1139. doi:10.1001/jama.2021.15936
Health Agencies Update

COVID-19 Vaccine Nasal Spray

Abstract Full Text
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JAMA. 2021;326(12):1138. doi:10.1001/jama.2021.14996

New Grants for Suicide Prevention

Abstract Full Text
JAMA. 2021;326(12):1138. doi:10.1001/jama.2021.15923

Tracking COVID-19 Supply Shortages

Abstract Full Text
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JAMA. 2021;326(12):1138. doi:10.1001/jama.2021.15924
Poetry and Medicine

Time of Death

Abstract Full Text
JAMA. 2021;326(12):1217. doi:10.1001/jama.2021.11525
JAMA Revisited

A Comparison of Greek and Modern Scientific Methods

Abstract Full Text
JAMA. 2021;326(12):1218. doi:10.1001/jama.2020.18146
JAMA Patient Page

Use of Aspirin During Pregnancy to Prevent Preeclampsia

Abstract Full Text
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JAMA. 2021;326(12):1222. doi:10.1001/jama.2021.15900

This JAMA Patient Page summarizes the US Preventive Services Task Force’s recent recommendations on using aspirin during pregnancy to prevent preeclampsia and preeclampsia-related complications.

Comment & Response

Association of Coronary Artery Bypass Grafting vs Percutaneous Coronary Intervention With Memory Decline in Older Adults

Abstract Full Text
JAMA. 2021;326(12):1212-1213. doi:10.1001/jama.2021.11976

Association of Coronary Artery Bypass Grafting vs Percutaneous Coronary Intervention With Memory Decline in Older Adults—Reply

Abstract Full Text
JAMA. 2021;326(12):1213. doi:10.1001/jama.2021.11978

Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy and Body Weight in Adults With Overweight or Obesity

Abstract Full Text
JAMA. 2021;326(12):1213-1214. doi:10.1001/jama.2021.13021

Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy and Body Weight in Adults With Overweight or Obesity—Reply

Abstract Full Text
JAMA. 2021;326(12):1214-1215. doi:10.1001/jama.2021.13024
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2021;326(12):1133-1134. doi:10.1001/jama.2020.18143
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