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November 2021 - July 1883

Decade

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Issue

October 12, 2021, Vol 326, No. 14, Pages 1353-1452

In This Issue of JAMA

Audio Highlights

Abstract Full Text
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JAMA. 2021;326(14):e2018169. doi:10.1001/jama.2020.18169
Original Investigation

Effect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms: A Randomized Clinical Trial

Abstract Full Text
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JAMA. 2021;326(14):1381-1389. doi:10.1001/jama.2021.14892

This randomized clinical trial examines the efficacy of fractional carbon dioxide laser for the management of vaginal symptoms associated with menopause.

Surveillance for Adverse Events After COVID-19 mRNA Vaccination

Abstract Full Text
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JAMA. 2021;326(14):1390-1399. doi:10.1001/jama.2021.15072

This study reports an interim analysis of safety surveillance data of 23 serious outcomes following vaccination with 1 of the mRNA COVID-19 vaccines based on comprehensive health records from a large US population.

Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021

Abstract Full Text
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JAMA. 2021;326(14):1400-1409. doi:10.1001/jama.2021.15161

This study estimates trends in SARS-CoV-2 seroprevalence related to infection and vaccination in the US population.

Research Letter

Changes in Body Mass Index Among Children and Adolescents During the COVID-19 Pandemic

Abstract Full Text
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JAMA. 2021;326(14):1434-1436. doi:10.1001/jama.2021.15036

This study compares body mass index (BMI) of youths during the COVID-19 pandemic with BMI during the same period in 2019 to determine whether they experienced pandemic-related weight gain.

Prevalence of SARS-CoV-2 Antibodies From a National Serosurveillance of Kenyan Blood Donors, January-March 2021

Abstract Full Text
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JAMA. 2021;326(14):1436-1438. doi:10.1001/jama.2021.15265

This study examines the prevalence of SARS-CoV-2 antibodies among blood donors aged 16 to 64 years in Kenya from January to March 2021.

US Preventive Services Task Force

Incorporation of Social Risk in US Preventive Services Task Force Recommendations and Identification of Key Challenges for Primary Care

Abstract Full Text
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JAMA. 2021;326(14):1410-1415. doi:10.1001/jama.2021.12833

This report from the US Preventive Services Task Force (USPSTF) identifies how social risks have been considered in the USPSTF recommendation statements and provides a foundation for ongoing work to ensure that health equity and social risks are incorporated in USPSTF methods and recommendations.

Screening and Interventions for Social Risk Factors: Technical Brief to Support the US Preventive Services Task Force

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JAMA. 2021;326(14):1416-1428. doi:10.1001/jama.2021.12825

This technical brief to support the US Preventive Services Task Force (USPSTF) describes current research on screening and interventions for social risk factors such as food insecurity, financial strain, and housing instability to inform USPSTF considerations of the implications for its portfolio of recommendations.

Viewpoint

A Middle Ground for Accelerated Drug Approval—Lessons From Aducanumab

Abstract Full Text
JAMA. 2021;326(14):1367-1368. doi:10.1001/jama.2021.14861

This Viewpoint offers potential changes to improve the process of US Food and Drug Administration accelerated approval.

Breakthrough Discovery in Protein Structure Prediction and the Promise of New Treatments

Abstract Full Text
JAMA. 2021;326(14):1369-1370. doi:10.1001/jama.2021.15728

This Viewpoint discusses protein folding and the use of computers to solve the protein folding problem along with the limitations of protein structure prediction and the practical benefits that may be yielded from the breakthrough discovery.

A Court Decision on “Skinny Labeling”: Another Challenge for Less Expensive Drugs

Abstract Full Text
JAMA. 2021;326(14):1371-1372. doi:10.1001/jama.2021.0006

This Viewpoint explains how “skinny labeling” works (bioequivalent drugs approved for unpatented uses and excluding patented indications from the generic drug’s labeling), the uncertainty about this pathway, and how the government and generic manufacturers can help restore timely generic competition in the face of brand-name drugs protected by patents.

A Piece of My Mind

Our Best Judgment

Abstract Full Text
JAMA. 2021;326(14):1373-1374. doi:10.1001/jama.2021.16348

In this narrative medicine essay, a palliative medicine physician describes his brother's hospitalization and death from COVID-19. He reflects on his brother's ability to achieve a dignified death because the physicians caring for him honestly assessed his prognosis.

Editorial

Safety Surveillance of COVID-19 mRNA Vaccines Through the Vaccine Safety Datalink

Abstract Full Text
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JAMA. 2021;326(14):1375-1377. doi:10.1001/jama.2021.14808

Time for a “Pause” on the Use of Vaginal Laser

Abstract Full Text
JAMA. 2021;326(14):1378-1380. doi:10.1001/jama.2021.14809
JAMA Insights

Women's Health

Treatment of Women After Bilateral Salpingo-oophorectomy Performed Prior to Natural Menopause

Abstract Full Text
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JAMA. 2021;326(14):1429-1430. doi:10.1001/jama.2021.3305

This Insight reviews adverse health effects of bilateral salpingo-oophorectomy in women prior to the age of natural menopause, and details treatment of such women.

From The Medical Letter on Drugs and Therapeutics

Sodium Sulfate–Based Tablets (Sutab) for Colonoscopy Preparation

Abstract Full Text
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JAMA. 2021;326(14):1431-1432. doi:10.1001/jama.2021.3606

This Medical Letter review summarizes the use of Sutab, an oral tablet formulation of sodium sulfate, magnesium sulfate, and potassium chloride, for colon cleansing prior to colonoscopy in adults.

Medical News & Perspectives

COVID-19 Testing Moves Out of the Clinic and Into the Home

Abstract Full Text
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JAMA. 2021;326(14):1362-1364. doi:10.1001/jama.2021.15679

This Medical News feature examines the growing use of over-the-counter rapid antigen tests for SARS-CoV-2 infection.

News From the Centers for Disease Control and Prevention

Delta Variant Linked With Spike in Youth Hospitalizations

Abstract Full Text
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JAMA. 2021;326(14):1366. doi:10.1001/jama.2021.16667

HPV Vaccination Coverage Has Increased Among Adolescents

Abstract Full Text
JAMA. 2021;326(14):1366. doi:10.1001/jama.2021.16574
Biotech Innovations

Moderna’s mRNA Vaccine for Seasonal Flu Enters Clinical Trials

Abstract Full Text
JAMA. 2021;326(14):1365. doi:10.1001/jama.2021.17499

India’s New COVID-19 DNA Vaccine for Adolescents and Adults Is a First

Abstract Full Text
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JAMA. 2021;326(14):1365. doi:10.1001/jama.2021.16625

Vaccine-Induced SARS-CoV-2 Antibodies in Inflammatory Diseases

Abstract Full Text
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JAMA. 2021;326(14):1365. doi:10.1001/jama.2021.17500
Poetry and Medicine

Your Ghost

Abstract Full Text
JAMA. 2021;326(14):1447. doi:10.1001/jama.2021.11653
JAMA Revisited

The Spirit of Revolt

Abstract Full Text
JAMA. 2021;326(14):1448. doi:10.1001/jama.2020.18170
JAMA Patient Page

Mechanical Ventilation

Abstract Full Text
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JAMA. 2021;326(14):1452. doi:10.1001/jama.2021.13084

This JAMA Patient Page describes the 2 types of mechanical ventilation, noninvasive and invasive, and how they are used in the management of hospitalized patients.

Comment & Response

Continuous Glucose Monitoring Use and Access Disparities

Abstract Full Text
JAMA. 2021;326(14):1438. doi:10.1001/jama.2021.13481

Continuous Glucose Monitoring Use and Access Disparities—Reply

Abstract Full Text
JAMA. 2021;326(14):1438. doi:10.1001/jama.2021.13484

Implantable vs Prolonged External Electrocardiographic Monitoring for Atrial Fibrillation Detection in Patients With Ischemic Stroke

Abstract Full Text
JAMA. 2021;326(14):1439. doi:10.1001/jama.2021.13487

Implantable vs Prolonged External Electrocardiographic Monitoring for Atrial Fibrillation Detection in Patients With Ischemic Stroke—Reply

Abstract Full Text
JAMA. 2021;326(14):1439-1440. doi:10.1001/jama.2021.13490
Correction

Error in Results

Abstract Full Text
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JAMA. 2021;326(14):1440. doi:10.1001/jama.2021.16131

Editorial on Screening for Chlamydia and Gonorrhea Corrected

Abstract Full Text
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JAMA. 2021;326(14):1440. doi:10.1001/jama.2021.16630
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2021;326(14):1353-1354. doi:10.1001/jama.2020.18167
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