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November 2021 - July 1883

Decade

Year

Issue

November 16, 2021, Vol 326, No. 19, Pages 1891-1983

In This Issue of JAMA

Audio Highlights

Abstract Full Text
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JAMA. 2021;326(19):e2018229. doi:10.1001/jama.2020.18229
Original Investigation

Effect of Sacubitril/Valsartan vs Standard Medical Therapies on Plasma NT-proBNP Concentration and Submaximal Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction: The PARALLAX Randomized Clinical Trial

Abstract Full Text
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JAMA. 2021;326(19):1919-1929. doi:10.1001/jama.2021.18463

This trial tested the efficacy of sacubitril/valsartan vs standard care in reducing NT-proBNP levels and improving exercise capacity and quality of life in patients with chronic heart failure.

Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar

Abstract Full Text
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JAMA. 2021;326(19):1930-1939. doi:10.1001/jama.2021.19623

This cohort study assesses protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 infection.

Association Between COVID-19 Diagnosis and In-Hospital Mortality in Patients Hospitalized With ST-Segment Elevation Myocardial Infarction

Abstract Full Text
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JAMA. 2021;326(19):1940-1952. doi:10.1001/jama.2021.18890

This cohort study examines the association between COVID-19 and ST-segment elevation myocardial infarction (STEMI) outcome in a large, nationally representative patient cohort who presented with out-of-hospital STEMI or developed STEMI while hospitalized.

Research Letter

Prehospital Treatment of Status Epilepticus in the United States

Abstract Full Text
JAMA. 2021;326(19):1970-1971. doi:10.1001/jama.2021.15964

This study assesses whether patients with status epilepticus are receiving first-line treatment consistent with current guidelines.

Changes in COVID-19 Vaccine Intent From April/May to June/July 2021

Abstract Full Text
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JAMA. 2021;326(19):1971-1974. doi:10.1001/jama.2021.18761

This study uses data from a nationally representative longitudinal study of adults in the US to examine individual-level change in vaccine intent and uptake between April and July 2021.

US Preventive Services Task Force

USPSTF Approach to Addressing Sex and Gender When Making Recommendations for Clinical Preventive Services

Abstract Full Text
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JAMA. 2021;326(19):1953-1961. doi:10.1001/jama.2021.15731

This report describes methods used by the US Preventive Services Task Force (USPSTF) to identify USPSTF recommendations that have sex or gender components and clarify the populations for which the recommendations should apply and also proposes an approach to making recommendations that are respectful of gender diversity.

Viewpoint

Diagnostic Excellence

Diagnostic Excellence

Abstract Full Text
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JAMA. 2021;326(19):1905-1906. doi:10.1001/jama.2021.19493

This Viewpoint launches a series of articles that will explore the multiple dimensions of achieving diagnostic excellence in the 21st century.

Diagnostic Excellence

Diagnosis and the Illness Experience: Ways of Knowing

Abstract Full Text
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JAMA. 2021;326(19):1907-1908. doi:10.1001/jama.2021.19496

This Viewpoint, part of a new JAMA series on diagnostic excellence, explores the meaning of diagnosis and the ultimate goal of using the diagnosis to provide individualized treatment and the art of caring to bring comfort to the patient experiencing illness.

The Financial Effects and Consequences of COVID-19: A Gathering Storm

Abstract Full Text
JAMA. 2021;326(19):1909-1910. doi:10.1001/jama.2021.18863

This Viewpoint reviews the US government’s apt financial response to patients and health care institutions during the COVID-19 pandemic, programs that are about to sunset, and reviews how the removal of those programs could devastate low-income families and health care institutions.

A Piece of My Mind

What Makes Us Know We’re Alive

Abstract Full Text
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JAMA. 2021;326(19):1911-1912. doi:10.1001/jama.2021.19481

In this narrative medicine essay, a pediatric hematology-oncology fellow weaves the strands of her life—emotional exhaustion from her first year of fellowship, the death of a friend, challenging bike rides, a husband who listens and doesn’t fix—moments that taken together mend her.

Editorial

Quality of Life and Exercise Ability in Heart Failure With Preserved Ejection Fraction: No Time for Therapeutic Complacency

Abstract Full Text
JAMA. 2021;326(19):1913-1915. doi:10.1001/jama.2021.15874

Myocardial Infarction During the COVID-19 Pandemic

Abstract Full Text
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JAMA. 2021;326(19):1916-1918. doi:10.1001/jama.2021.19608
JAMA Insights

Women's Health

Evaluation and Management of Amenorrhea

Abstract Full Text
JAMA. 2021;326(19):1962-1963. doi:10.1001/jama.2021.13312

This JAMA Insights article in the Women’s Health series examines the diagnosis, evaluation, and management of amenorrhea.

JAMA Clinical Guidelines Synopsis

Managing Adult Acute and Acute-on-Chronic Liver Failure in the ICU

Abstract Full Text
JAMA. 2021;326(19):1964-1965. doi:10.1001/jama.2021.12742

This JAMA Clinical Guidelines Synopsis summarizes guidelines from the Society of Critical Care Medicine on managing adult liver failure in the ICU.

JAMA Diagnostic Test Interpretation

Electrodiagnostic Testing for Diagnosing Polyneuropathy

Abstract Full Text
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JAMA. 2021;326(19):1966-1967. doi:10.1001/jama.2021.19286

A 50-year-old woman with a history of seizures presented to the electromyography laboratory with progressive lower extremity pain and gait imbalance. Results of nerve conduction studies showed an absent sural sensory response and decreased amplitudes of peroneal motor and radial sensory responses. How do you interpret these results?

Medical News & Perspectives

Monoclonal Antibodies for COVID-19 Preexposure Prophylaxis Can’t Come Fast Enough for Some People

Abstract Full Text
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JAMA. 2021;326(19):1895-1897. doi:10.1001/jama.2021.19534

This Medical News feature discusses the use of anti–SARS-CoV-2 monoclonal antibodies for preexposure prophylaxis in people with compromised immune systems.

News From the Food and Drug Administration

Surgical Staplers to Undergo More Stringent Review for Safety Reasons

Abstract Full Text
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JAMA. 2021;326(19):1899. doi:10.1001/jama.2021.20109

Some Companies Will Stop Making Alcohol-Based Hand Sanitizer

Abstract Full Text
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JAMA. 2021;326(19):1899. doi:10.1001/jama.2021.19919

Needle-Free Dermal Filler Injectors Prompt Safety Warning

Abstract Full Text
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JAMA. 2021;326(19):1899. doi:10.1001/jama.2021.20110
Global Health

Global Plan Targets Elimination of Bacterial Meningitis Epidemics

Abstract Full Text
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JAMA. 2021;326(19):1898. doi:10.1001/jama.2021.19580

WHO, Global Health Workers Demand Urgent Action on Climate Change

Abstract Full Text
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JAMA. 2021;326(19):1898. doi:10.1001/jama.2021.20063

Lack of Adolescents’ Mental Health Care Is a Global Challenge

Abstract Full Text
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JAMA. 2021;326(19):1898. doi:10.1001/jama.2021.20064
Poetry and Medicine

Last-Minute Pedicure

Abstract Full Text
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JAMA. 2021;326(19):1979. doi:10.1001/jama.2021.13696
JAMA Revisited

“Opium Antidotes,” and Their Vendors: J. B. Mattison, M.D.

Abstract Full Text
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JAMA. 2021;326(19):1980. doi:10.1001/jama.2020.18230
JAMA Patient Page

Bell Palsy

Abstract Full Text
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JAMA. 2021;326(19):1983. doi:10.1001/jama.2021.18504

This JAMA Patient Page describes Bell palsy, a form of facial weakness or paralysis that typically affects one side of the face, and its symptoms and treatment.

Comment & Response

Platelet-Rich Plasma Injection vs Sham Injection and Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy

Abstract Full Text
JAMA. 2021;326(19):1974. doi:10.1001/jama.2021.16055

Platelet-Rich Plasma Injection vs Sham Injection and Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy

Abstract Full Text
JAMA. 2021;326(19):1974-1975. doi:10.1001/jama.2021.16052

Platelet-Rich Plasma Injection vs Sham Injection and Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy

Abstract Full Text
JAMA. 2021;326(19):1975. doi:10.1001/jama.2021.16049

Platelet-Rich Plasma Injection vs Sham Injection and Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy—Reply

Abstract Full Text
JAMA. 2021;326(19):1975-1976. doi:10.1001/jama.2021.16067

A Review of the Diagnosis and Treatment of Alcohol-Associated Liver Disease

Abstract Full Text
JAMA. 2021;326(19):1976. doi:10.1001/jama.2021.16058

A Review of the Diagnosis and Treatment of Alcohol-Associated Liver Disease—Reply

Abstract Full Text
JAMA. 2021;326(19):1976-1977. doi:10.1001/jama.2021.16070

A Hospital and Postdischarge Quality Improvement Intervention and Outcomes and Care for Patients With Heart Failure With Reduced Ejection Fraction

Abstract Full Text
JAMA. 2021;326(19):1977. doi:10.1001/jama.2021.16753

A Hospital and Postdischarge Quality Improvement Intervention and Outcomes and Care for Patients With Heart Failure With Reduced Ejection Fraction—Reply

Abstract Full Text
JAMA. 2021;326(19):1977-1978. doi:10.1001/jama.2021.16756
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2021;326(19):1891-1892. doi:10.1001/jama.2020.18227
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