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September 2021 - July 1883

Decade

Year

Issue

September 7, 2021, Vol 326, No. 9, Pages 793-880

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2021;326(9):e2018109. doi:10.1001/jama.2020.18109
Original Investigation

Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial

Abstract Full Text
has multimedia has audio
JAMA. 2021;326(9):818-829. doi:10.1001/jama.2021.11684

This randomized clinical trial compares the effect of a balanced solution vs saline solution on 90-day survival in critically ill patients.

Effect of Slower vs Faster Intravenous Fluid Bolus Rates on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial

Abstract Full Text
has multimedia has audio
JAMA. 2021;326(9):830-838. doi:10.1001/jama.2021.11444

This factorial clinical trial examined whether infusing critically ill patients in the intensive care unit requiring fluid challenges at a slower rate than a faster rate would reduce 90-day mortality.

Effect of School Integrated Pest Management or Classroom Air Filter Purifiers on Asthma Symptoms in Students With Active Asthma: A Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA. 2021;326(9):839-850. doi:10.1001/jama.2021.11559

This randomized clinical trial compares use of a school-wide integrated pest management (IPM) program vs use of high-efficiency particulate air (HEPA) filter purifiers in the classrooms for students with active asthma attending urban elementary schools who were randomized to IPM by school and HEPA filter purifiers by classroom.

Research Letter

Age-Dependent Neutralization of SARS-CoV-2 and P.1 Variant by Vaccine Immune Serum Samples

Abstract Full Text
free access has active quiz
JAMA. 2021;326(9):868-869. doi:10.1001/jama.2021.11656

This study examines the relationship between age and neutralizing antibody titers against the SARS-CoV-2 USA-WA1/2020 strain and the P.1 variant after 2 doses of the BNT162b2 vaccine.

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents

Abstract Full Text
free access has active quiz
JAMA. 2021;326(9):869-871. doi:10.1001/jama.2021.11880

This cohort study reports the prevalence of long-term symptoms in children and adolescents who had recovered from acute SARS-CoV-2 infection.

Viewpoint

Aligning Payments, Services, and Quality in Primary Care

Abstract Full Text
JAMA. 2021;326(9):805-806. doi:10.1001/jama.2021.12775

This Viewpoint suggests a hybrid reimbursement model for primary care practices that could help align payments and practice structure with the types and intensity of services that patients need.

Enforcement of the Physician Payments Sunshine Act: Trust and Verify

Abstract Full Text
JAMA. 2021;326(9):807-808. doi:10.1001/jama.2021.13156

This Viewpoint revisits the Open Payments Program, mandated by the Sunshine Act, and discusses alleged violations by device and pharmaceutical manufacturers and the future enforcement of the program.

Cancer as a Global Health Priority

Abstract Full Text
JAMA. 2021;326(9):809-810. doi:10.1001/jama.2021.12778

This Viewpoint discusses the mission, vision, and goals of the US National Cancer Institute Center for Global Health on the 10th anniversary of creation of the Center, which was established to incorporate cancer control into broader global health programs, foster relevant research, and cultivate collaborations among researchers with shared global health objectives.

A Piece of My Mind

Drifting Over the Horizon: Navigating the End-of-Life Journey

Abstract Full Text
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JAMA. 2021;326(9):811-812. doi:10.1001/jama.2021.14031

In this narrative medicine essay, a geriatrician describes how his mother and he navigate the last months and days of her life while basking in their mutual love, trust, and respect.

Editorial

Does Crystalloid Composition or Rate of Fluid Administration Make a Difference When Resuscitating Patients in the ICU?

Abstract Full Text
has audio
JAMA. 2021;326(9):813-815. doi:10.1001/jama.2021.11119

School Classrooms as Targets to Reduce Allergens and Improve Asthma

Abstract Full Text
JAMA. 2021;326(9):816-817. doi:10.1001/jama.2021.12322
Review

Pancreatic Cancer: A Review

Abstract Full Text
has active quiz
JAMA. 2021;326(9):851-862. doi:10.1001/jama.2021.13027

This review summarizes current evidence regarding pathobiology, diagnosis, and management of pancreatic ductal adenocarcinoma.

JAMA Insights

Cognitive Decline Associated With Anesthesia and Surgery in Older Patients

Abstract Full Text
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JAMA. 2021;326(9):863-864. doi:10.1001/jama.2021.4773

This JAMA Insights article reviews how changes in the brain related to aging may contribute to decreased cognitive reserve, susceptibility to the stresses of surgery and anesthesia, and increased risk of neurologic injury from anesthesia and surgery in older patients.

JAMA Clinical Challenge

Inflammatory Myositis in a Patient With Melanoma

Abstract Full Text
has active quiz
JAMA. 2021;326(9):865-866. doi:10.1001/jama.2021.9025

A 47-year-old man with melanoma presented with 1 week of low-grade fevers, myalgias, elevated creatine kinase levels, and proximal muscle weakness. He previously underwent amputation of a finger and began adjuvant nivolumab for stage IIIC melanoma. One week later, he developed fevers, myalgias, dark urine, weakness, and difficulty walking. What is the diagnosis and what would you do next?

Medical News & Perspectives

Detecting Kids’ Broken Hearts—Cardiac Screening Advised During Well-Child Visits

Abstract Full Text
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JAMA. 2021;326(9):797-799. doi:10.1001/jama.2021.13323

This Medical News article discusses new American Academy of Pediatrics policy that advises universal cardiac screening for children and adolescents.

News From the JAMA Network

Most Fully Vaccinated Patients With Cancer Have SARS-CoV-2 Antibodies

Abstract Full Text
JAMA. 2021;326(9):800. doi:10.1001/jama.2021.14707

Covering Tracheostomies Reduces Viral Spread to Health Care Staff

Abstract Full Text
JAMA. 2021;326(9):800. doi:10.1001/jama.2021.13454

Novel Oral Drug Rapidly Treats Postpartum Depression

Abstract Full Text
JAMA. 2021;326(9):800. doi:10.1001/jama.2021.14708

Guidelines for Lipid-Lowering Therapy Intensification Rarely Followed

Abstract Full Text
JAMA. 2021;326(9):800. doi:10.1001/jama.2021.14709
News From the Food and Drug Administration

First Interchangeable Biosimilar Insulin Drug Is Approved

Abstract Full Text
free access
JAMA. 2021;326(9):801. doi:10.1001/jama.2021.14729

Testing Monoclonal Antibodies for Rabies Prophylaxis

Abstract Full Text
free access
JAMA. 2021;326(9):801. doi:10.1001/jama.2021.13757

Developing Partnerships to Streamline Global Food Safety

Abstract Full Text
free access
JAMA. 2021;326(9):801. doi:10.1001/jama.2021.14730
The Arts and Medicine

Emoji for the Medical Community—Challenges and Opportunities

Abstract Full Text
free access
JAMA. 2021;326(9):795-796. doi:10.1001/jama.2021.8409

This Arts and Medicine feature reviews currently available medical emoji and proposes that an expanded set of images could improve medical communication, clinical care, and public health.

Poetry and Medicine

Sequelae

Abstract Full Text
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JAMA. 2021;326(9):874. doi:10.1001/jama.2021.9462
JAMA Revisited

Public Health and Private Practice

Abstract Full Text
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JAMA. 2021;326(9):875. doi:10.1001/jama.2020.18110
JAMA Patient Page

Variants of SARS-CoV-2

Abstract Full Text
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JAMA. 2021;326(9):880. doi:10.1001/jama.2021.14181

This JAMA Patient Page explains what virus variants are and describes several recent variants of the SARS-CoV-2 virus and the public health concerns relating to these variants.

Comment & Response

Age at Diabetes Onset and Subsequent Risk of Dementia

Abstract Full Text
JAMA. 2021;326(9):871. doi:10.1001/jama.2021.10485

Age at Diabetes Onset and Subsequent Risk of Dementia—Reply

Abstract Full Text
JAMA. 2021;326(9):871-872. doi:10.1001/jama.2021.10488

Half-Dose vs Stable-Dose Conventional Synthetic Disease-Modifying Antirheumatic Drugs and Disease Flare in Patients With Rheumatoid Arthritis

Abstract Full Text
JAMA. 2021;326(9):872-873. doi:10.1001/jama.2021.10648

Half-Dose vs Stable-Dose Conventional Synthetic Disease-Modifying Antirheumatic Drugs and Disease Flare in Patients With Rheumatoid Arthritis—Reply

Abstract Full Text
JAMA. 2021;326(9):873. doi:10.1001/jama.2021.10651
Correction

Error in Letter to the Editor

Abstract Full Text
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JAMA. 2021;326(9):873. doi:10.1001/jama.2021.12604

Incorrect Classification of Pharmaceutical Agent

Abstract Full Text
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JAMA. 2021;326(9):873. doi:10.1001/jama.2021.14278

Incorrect Description in Patient Page

Abstract Full Text
free access
JAMA. 2021;326(9):873. doi:10.1001/jama.2021.14302
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2021;326(9):793-794. doi:10.1001/jama.2020.18107
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