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This study examines discharge trends for opioid-related admissions from 2016-2020 with a focus on admissions with opioid use disorder and an injection-related infection.

A patient had cold, cyanotic fingertips with small ulcerations. Laboratory testing showed leukocytosis, eosinophilia, and elevated D-dimer level; results of tests for antinuclear antibodies, antiphospholipid antibodies, antineutrophil cytoplasmic antibodies against proteinase 3 and myeloperoxidase, and HIV were negative. What is the diagnosis and what would you do next?

This Arts and Medicine feature reviews 4 health-related graphic medicine (comic) projects judged as the best of 2022 by the Graphic Medicine International Collective.

This randomized trial assesses whether prone vs supine positioning decreases the time to successful weaning of extracorporeal membrane oxygenation (ECMO) in patients with severe acute respiratory distress syndrome (ARDS).

In this narrative medicine essay, an internal medicine physician, invited to speak at an International AIDS Society plenary session about his HIV work, endures a cool response from his parents upon sharing his HIV status but is met with a standing ovation and cheered by his chosen family and friends after the speech.

A 72-year-old man presented to the emergency department with fevers, night sweats, and rash 3 days after condomless vaginal intercourse. Results of a fourth-generation HIV test were positive and HIV-1-/2 antibody differentiation testing was negative. How would you interpret these results?

This JAMA Patient Page describes the condition of prediabetes and its symptoms, diagnosis, and management strategies.