This Viewpoint discusses the use of artificial intelligence in health care and its potential effect on how patients access care and how physicians and patients make decisions.
This cohort study uses UK Biobank data to examine interactions between polygenic risk for Alzheimer disease and lifestyle (physical activity, healthy diet, moderate alcohol drinking) and their associations with incident all-cause dementia.
This Viewpoint discusses the potential risks faced by pregnant women with substance use disorders who participate in clinical research, including criminal prosecution for drug use while pregnant and custody loss of their children, and proposes changes to research procedures and disclosure provisions to encourage their participation so the evidence base informing their care and addressing the opioid epidemic more generally can advance.
This Viewpoint argues for integration of price information in electronic health records (EHRs) as a mechanism to increase price transparency and promote cost-conscious, patient-centered, shared decision making at the point of care.
In May 2019 the US Supreme Court sent back to lower courts the question of whether Merck Sharpe & Dohme Corp was liable for atypical fractures from its osteoporosis drug alendronate because it did not identify the adverse effect in the product’s label. This Viewpoint discusses the legal questions of liability raised by the case and the implication of the decision for the pharmaceutical industry and for patients alleging harmed from prescription drugs.
This JAMA Insights Clinical Update reviews bone turnover markers measurable in blood and urine and summarizes evidence supporting their use to predict osteoporosis and osteoporotic fractures, assess treatment adherence and efficacy, and monitor bone loss after drug discontinuation.
In this Arts and Medicine feature, author Samuel Shem (pen name of Stephen Bergman, MD) reflects on the origins of his classic novel The House of God, the people and events that inspired its stories, the notion of “fiction as resistance,” and the evolving meaning of the book given developments in medicine and medical education in the 40 years since its publication.
In this Arts and Medicine feature, an early-career physician discusses the ongoing relevance of Samuel Shem’s novel, The House of God, to contemporary health care and medical education on the occasion of its 40th anniversary of publication.
This Viewpoint argues for thinking about improvements in the care of new moms and infants as a single entity, and discusses regionalization of obstetric and infant care as a way to operationalize the idea and achieve simultaneous improvements in maternal and neonatal outcomes.
This Viewpoint argues that buprenorphine be made available without prescription behind the counter at retail pharmacies with age and quantity restrictions similar to those used for pseudoephedrine, and addresses concerns raised by the access model about safety and diversion.
This Viewpoint reviews new findings presented at a 2019 NIH conference about neuroendocrine, metabolic, immunologic, and physiologic abnormalities that contribute to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
A 41-year-old woman with an 8–pack-year history of tobacco use had 4 years of progressive cough and dyspnea. She had no history of neonatal respiratory distress or nasal congestion and no family history of COPD or cystic fibrosis; pulmonary function testing showed a severe obstruction and chest CT showed lower lobe predominant emphysema and bronchiectasis. What is the diagnosis and what would you do next?
This Medical News story examines the popularity of the “Marik protocol,” a combination of high–dose vitamin C, corticosteroids, and thiamine to treat sepsis.
This Medical News story discusses recent research examining whether the appendix plays a role in Parkinson disease risk.
This Viewpoint discusses the CMS Open Payments program, which publicizes payments made by medical device firms and pharmaceutical companies to physicians, and proposes ways the payment information can be better used to inform and empower patients and discourage physicians from excessively profiting from industry.
This JAMA Insights Clinical Update reviews approaches to imaging that are safe for the developing fetus in pregnant women with abdominal pain.
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