In the context of a concerning increase in rates of syphilis and congenital syphilis in the United States, this Viewpoint discusses the importance of improving screening programs and diagnostics, and it argues for legislation, media coverage, and activism by patient advocacy groups and policy makers to remove the stigma of this resurgent sexually transmitted infection (STI).
A 40-year-old woman with Graves disease presented with abdominal pain and constipation. Thyroid-stimulating hormone was undetectable and physical examination revealed a tender midline abdominal mass. Three months earlier she was evaluated for 3 to 4 months of amenorrhea, and a urine human chorionic gonadotropin test was negative for pregnancy. What would you do next?
This pharmacoepidemiology study uses Canadian health care database data to estimate the risk of encephalopathy among patients with chronic kidney disease (CKD) in Ontario prescribed higher (≥20 mg) vs lower (<20 mg) doses of baclofen.
This 2 × 2 factorial trial compares the effects of vitamin D3 vs placebo and omega-3 fatty acids vs placebo on change in glomerular filtration rate estimated from serum creatinine and cystatin C (eGFR) over 5 years in adults with type 2 diabetes.
This study pools data from 34 cohorts participating in the CKD Prognosis Consortium developed a risk equation to predict risk of incident chronic kidney disease (CKD) defined as an estimated glomerular filtration rate of less than 60 mL/min/1.73 m2.
This Viewpoint attempts to provide public health context to the 2019 emergence of e-cigarette, or vaping, product use–associated lung injury (EVALI), emphasizing that EVALI is likely caused by vaping exposure to THC-containing products and is a public health risk far less than that of smoking combustible tobacco, and suggesting ways physicians might use awareness of the phenomenon to counsel patients about the risks of smoking electronic and traditional cigarettes.
This Viewpoint reviews the features of managed care organizations (MCOs) and managed competition, which seek to incentivize high-quality care and control spending through care coordination and shared financial risk and savings, and argues that the 2 are imperfect approaches to health care and payment reform but the most promising options for controlling costs short of price controls.
This Medical Letter review summarizes types and use of commercially available inactivated and activated trivalent and quadrivalent influenza vaccines, with recommendations for which to use in patients who are pregnant, allergic, or immunocompromised.
This Medical News article discusses the urgent need for a more broadly protective, durable influenza vaccine—and advancements toward it.
This Medical News article discusses knowledge deficiencies and health system barriers that keep some primary care physicians from caring adequately for patients with prediabetes.
This study uses 2019 National Youth Tobacco Survey data to estimate the prevalence of e-cigarette use among high school and middle school students and the frequency of use, brands used (JUUL, blu, and others), and use of flavored products.
This national survey study characterizes JUUL e-cigarette flavors (mint, mango, fruit, and others) most often used by US middle school and high school students in 2019.
This Viewpoint uses findings from a 2019 Centers for Disease Control and Prevention (CDC) report detailing the prevalence and long-term harms of adverse childhood experiences (ACEs) to emphasize ways pediatricians can identify patients experiencing ACEs and intervene to prevent or reduce harms associated with the experiences.
This JAMA Insights Clinical Update summarizes treatment options for individuals with chronic idiopathic constipation, irritable bowel syndrome with constipation, and opioid-induced constipation and summarizes recent guidelines that conclude that traditional laxatives should be used as first-line agents for the management of constipation because of low cost and high benefit.
This JAMA Clinical Guidelines Synopsis summarizes the 2018 American Gastroenterological Association guideline on medical management of opioid-induced constipation.
This Viewpoint uses the example of the successes and failures of the tobacco industry’s Master Settlement Agreement to suggest a framework for redressing the current US opioid epidemic.
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