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Year

Day

September 20, 2019
Viewpoint

The Advancing American Kidney Health Executive Order: An Opportunity to Enhance Organ Donation

Abstract Full Text
free access has audio
JAMA. Published online September 20, 2019. doi:10.1001/jama.2019.14500

This Viewpoint uses provisions in President Trump’s 2019 American Kidney Health Executive order calling for an increase in access to kidney transplantation to discuss strategies to increase deceased and living donor pools, improve allocation of organs from higher-risk donors, and support the long-term medical needs of living donors.

Value-Based Purchasing and Physician Professionalism

Abstract Full Text
free access
JAMA. Published online September 20, 2019. doi:10.1001/jama.2019.14990

This Viewpoint discusses the importance of structuring value-based purchasing models around principles of physician professionalism to ensure that measures that lead to more payment are clinically meaningful, do not increase administrative burden, do not displace clinicians’ intrinsic motivation to help patients with financial motivations, and do not incentivize physicians to avoid sicker, more complicated patients.

September 19, 2019
Original Investigation

Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial

Abstract Full Text
free access
JAMA. Published online September 19, 2019. doi:10.1001/jama.2019.13772

This randomized noninferiority clinical trial examines the effect of treatment with the dipeptidyl peptidase-4 inhibitor linagliptin vs the commonly used sulfonylurea glimepiride on cardiovascular safety in patients with type 2 diabetes and cardiovascular risk factors or established atherosclerotic cardiovascular disease.

Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function

Abstract Full Text
free access
JAMA. Published online September 19, 2019. doi:10.1001/jama.2019.13206

This cohort study uses data from the National Veterans Health Administration, Medicare, Medicaid, and National Death Index to compare major adverse cardiovascular events among patients with diabetes and reduced kidney function who continued treatment with metformin or sulfonylurea.

Editorial

Sulfonylureas and Cardiovascular Safety: The Final Verdict?

Abstract Full Text
free access
JAMA. Published online September 19, 2019. doi:10.1001/jama.2019.14533
September 18, 2019
Medical News & Perspectives

Quick Uptakes

In Hot, Humid Weather, Fans Benefit Health and Environment

Abstract Full Text
free access
JAMA. Published online September 18, 2019. doi:10.1001/jama.2019.14684

This Medical News article discusses a recent study about the effect of fans on relieving the physiological stress of high temperatures.

Finding the Right Words to Stop Cancer Screening in Older Adults

Abstract Full Text
free access
JAMA. Published online September 18, 2019. doi:10.1001/jama.2019.14732

In this Medical News article, experts discuss sensitive ways to tell older adults that they no longer need cancer screening when their life expectancy is less than 10 years.

September 16, 2019
Research Letter

Prevalence of e-Cigarette Use Among Adults in the United States, 2014-2018

Abstract Full Text
JAMA. Published online September 16, 2019. doi:10.1001/jama.2019.15331

This population epidemiology study uses 2014-2018 data from National Health Interview Surveys to assess trends in prevalence of current and daily e-cigarette use by US adults and to characterize trends by sociodemographic and smoking status among young adults (18-24 years).

Editorial

The Ninth International Congress on Peer Review and Scientific Publication: A Call for Research

Abstract Full Text
free access
JAMA. Published online September 16, 2019. doi:10.1001/jama.2019.15516
September 13, 2019
Viewpoint

Redefining Heart Failure With a Reduced Ejection Fraction

Abstract Full Text
free access
JAMA. Published online September 13, 2019. doi:10.1001/jama.2019.15600

In this Viewpoint, Milton Packer and colleagues argue that reliance on a threshold of LVEF ≤40% to define heart failure with reduced ejection fraction (HFrEF) may exclude patients with impaired systolic function and subnormal LVEF from evidence-based treatments that reduce morbidity and mortality, and the authors propose that the LVEF threshold for HFrEF treatment be increased to ≤50%.

September 12, 2019
Viewpoint

Primary Care Selection: A Building Block for Value-Based Health Care

Abstract Full Text
free access
JAMA. Published online September 12, 2019. doi:10.1001/jama.2019.14190

In the context of “attribution gaps” that leave payers uncertain which physicians are to be credited with patient care quality and outcome measures in accountable care organization (ACO) payment models, this Viewpoint discusses the importance of patient selection of primary care providers to patient-centered value-based care, and changes CMS will need to implement to integrate the measure.

JAMA Diagnostic Test Interpretation

Point-of-Care Hemoglobin A1c

Abstract Full Text
has active quiz
JAMA. Published online September 12, 2019. doi:10.1001/jama.2019.14063

An asymptomatic 57-year-old man with obesity, hypertension, and dyslipidemia requests screening for diabetes. Would you offer laboratory-based or point-of-care glucose or HbA1c testing?

September 11, 2019
Medical News & Perspectives

Quick Uptakes

How Old Is Too Old to Be President?

Abstract Full Text
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JAMA. Published online September 11, 2019. doi:10.1001/jama.2019.14329

This Medical News article reports on a recent analysis that concludes that older candidates’ ages shouldn’t be a concern in the 2020 presidential election.

Cardiovascular Corner: Prescription Omega-3s, Stroke Rehab, and Statins After Age 75

Abstract Full Text
free access
JAMA. Published online September 11, 2019. doi:10.1001/jama.2019.14485

This Medical News article is an update on important clinical research in the world of heart disease and stroke.

September 10, 2019
Viewpoint

Discovery of 2 Distinctive Lineages of Lymphocytes, T Cells and B Cells, as the Basis of the Adaptive Immune System and Immunologic Function: 2019 Albert Lasker Basic Medical Research Award

Abstract Full Text
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JAMA. Published online September 10, 2019. doi:10.1001/jama.2019.13815

In this Viewpoint, 2019 Albert Lasker Basic Medical Research Award winners Max Dale Cooper and Jacques F. A. P. Miller discuss their discovery of B and T cells, which provided the organizing principle of the adaptive immune system and launched the course of modern immunology.

Biomarker-Driven Drug Discovery in Cancer—Trastuzumab Development: 2019 Lasker-DeBakey Clinical Medical Research Award

Abstract Full Text
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JAMA. Published online September 10, 2019. doi:10.1001/jama.2019.13963

In this Viewpoint, 2019 Lasker-DeBakey Clinical Medical Research Award winner H. Michael Shepard discusses development of trastuzumab, the first fully humanized monoclonal antibody for solid tumor treatment and the first tyrosine kinase inhibitor, for treatment of breast cancer.

The Power of Vaccines and How Gavi Has Helped Make the World Healthier: 2019 Lasker-Bloomberg Public Service Award

Abstract Full Text
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JAMA. Published online September 10, 2019. doi:10.1001/jama.2019.13190

In this Viewpoint, the CEO of Lasker-Bloomberg Public Service Award winner Gavi, the Vaccine Alliance, describes its work improving access to affordable childhood vaccines in low-income countries.

September 9, 2019
Viewpoint

The Relative Value Scale Update Committee: Time for an Update

Abstract Full Text
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JAMA. Published online September 9, 2019. doi:10.1001/jama.2019.14591

This Viewpoint discusses how problems with the methodology, structure, and recommendations of the Relative Value Scale Update Committee can lead to outdated or inaccurate physician payment data and lower quality of care, and calls for the use of empirical data and patient-specific outcomes to inform physician reimbursement.

September 6, 2019
Viewpoint

Medicaid Expansion and Health: Assessing the Evidence After 5 Years

Abstract Full Text
free access has audio
JAMA. Published online September 6, 2019. doi:10.1001/jama.2019.12345

This Viewpoint reviews evidence for associations between Medicaid expansion under the Affordable Care Act and self-reported health outcomes, condition-specific outcome measures from administrative data, and state and national health indicators for low-income populations.

JAMA Insights

Clinical Update

What Is Known About Candida auris

Abstract Full Text
JAMA. Published online September 6, 2019. doi:10.1001/jama.2019.13843

This JAMA Insights Clinical Update reviews infection control and treatment strategies to manage Candida auris, a new drug-resistant fungal species that can cause severe invasive infection with high morbidity and mortality in patients with underlying comorbid illnesses.

September 5, 2019
Viewpoint

What Is the Value of Market-Wide Health Care Price Transparency?

Abstract Full Text
free access has audio
JAMA. Published online September 5, 2019. doi:10.1001/jama.2019.11578

In the wake of a 2019 executive order requiring hospitals to publicly post paid prices and requiring clinicians, insurers, and health plans to provide estimated out-of-pocket costs to patients, this Viewpoint reviews available evidence about the likelihood that price transparency might influence consumer choice, put downward pressure on prices, and influence insurers to incentivize patients to seek lower-cost care.

JAMA Clinical Challenge

Joint Pain and Proteinuria

Abstract Full Text
has active quiz
JAMA. Published online September 5, 2019. doi:10.1001/jama.2019.12704

A 66-year-old man had bilateral carpal tunnel syndrome and 6 years of chronic joint pain and stiffness of the shoulders, hips, and knees. He reported occasional bruising around his eyes; physical examination showed raised soft tissue masses around the sternoclavicular joints and scapulae, and laboratory examination was notable for significant levels of protein and albumin. What is the diagnosis and what would you do next?

September 4, 2019
Medical News & Perspectives

Green Vegetables, Herbs, and Oils May Help Stabilize Patients Taking Warfarin

Abstract Full Text
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JAMA. Published online September 4, 2019. doi:10.1001/jama.2019.13060

This Medical News article discusses recent research that shows increasing their vitamin K intake could help patients who take warfarin to maintain stable anticoagulation.

Wild Health

Pigs Model Human Brains, Snake Fangs Inspire Microneedles, and Canines Advance Cardiac Imaging

Abstract Full Text
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JAMA. Published online September 4, 2019. doi:10.1001/jama.2019.12580

This Medical News article discusses how pigs, rear-fanged snakes, and dogs may help improve our understanding of brain connectivity, vaccine delivery, and myocardial oxygenation.

Comment & Response

Clarification of Reporting of Potential Conflicts of Interest in JAMA Articles

Abstract Full Text
JAMA. Published online September 4, 2019. doi:10.1001/jama.2019.12743
Correction

Clarification of Reporting of Potential Conflicts of Interest in 2 Articles

Abstract Full Text
free access
JAMA. Published online September 4, 2019. doi:10.1001/jama.2019.14523
September 2, 2019
Original Investigation

Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease

Abstract Full Text
JAMA. Published online September 2, 2019. doi:10.1001/jama.2019.14120

This genetic epidemiology study uses UK Biobank database data to estimate the association between genetic variants associated with lower low-density lipoprotein cholesterol (LDL-C), lower systolic blood pressure (SBP), or both and cardiovascular disease (CVD), defined as coronary death, nonfatal, myocardial infarction, or coronary revascularization.

Association of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity

Abstract Full Text
has audio
JAMA. Published online September 2, 2019. doi:10.1001/jama.2019.14231

This matched-cohort study uses Cleveland Clinic Health System data to investigate the association between bariatric surgery and major adverse cardiovascular events (MACE), including mortality, coronary disease and stroke, in adult patients with type 2 diabetes and obesity.

Editorial

The Role of Bariatric Surgery in Managing the Macrovascular Complications of Obesity-Related Type 2 Diabetes

Abstract Full Text
JAMA. Published online September 2, 2019. doi:10.1001/jama.2019.14577
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