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October 25, 2021
US Preventive Services Task Force

USPSTF Approach to Addressing Sex and Gender When Making Recommendations for Clinical Preventive Services

Abstract Full Text
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JAMA. Published online October 25, 2021. doi:10.1001/jama.2021.15731

This report describes methods used by the US Preventive Services Task Force (USPSTF) to identify USPSTF recommendations that have sex or gender components and clarify the populations for which the recommendations should apply and also proposes an approach to making recommendations that are respectful of gender diversity.

October 24, 2021
Research Letter

Incidence of Pancreatic Cancer by Age and Sex in the US, 2000-2018

Abstract Full Text
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JAMA. Published online October 24, 2021. doi:10.1001/jama.2021.18859

This study uses data from the Surveillance Epidemiology and End Results database to perform an age- and sex-specific time trend analysis of pancreatic cancer incidence rates in US adults.

October 22, 2021
Viewpoint

Focusing on Digital Health Equity

Abstract Full Text
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JAMA. Published online October 22, 2021. doi:10.1001/jama.2021.18459

This Viewpoint describes ways in which health care digital tools and platforms can be designed and implemented to address long-standing health equity disparities.

A Policy Prescription for Reducing Health Disparities—Achieving Pharmacoequity

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JAMA. Published online October 22, 2021. doi:10.1001/jama.2021.17764

This Viewpoint discusses pharmacoequity, which is the goal of ensuring that all individuals have access to the highest-quality medications required to manage their health needs, and ways in which this can be achieved.

October 21, 2021
Original Investigation

Caring for the Critically Ill Patient

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial

Abstract Full Text
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JAMA. Published online October 21, 2021. doi:10.1001/jama.2021.18295

This multicenter randomized clinical trial compares the effects of 12 mg/d vs 6 mg/d of dexamethasone in patients with COVID-19 and severe hypoxemia.

Editorial

Glucocorticoid Dose in COVID-19: Lessons for Clinical Trials During a Pandemic

Abstract Full Text
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JAMA. Published online October 21, 2021. doi:10.1001/jama.2021.16438
Medical News & Perspectives

The Flawed Science of Antibody Testing for SARS-CoV-2 Immunity

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JAMA. Published online October 21, 2021. doi:10.1001/jama.2021.18919

This Medical News article discusses why experts recommend against patients getting antibody testing to assess their protection from SARS-CoV-2 after vaccination or infection.

October 20, 2021
Viewpoint

Administrative Simplification and the Potential for Saving a Quarter-Trillion Dollars in Health Care

Abstract Full Text
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JAMA. Published online October 20, 2021. doi:10.1001/jama.2021.17315

This Viewpoint discusses a new report that describes steps that may be taken in specific areas to simplify administrative functions, reduce administrative spending, and boost overall productivity in US health care.

Administrative Expenses in the US Health Care System: Why So High?

Abstract Full Text
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JAMA. Published online October 20, 2021. doi:10.1001/jama.2021.17318

This Viewpoint discusses administrative expenses in the US health care system and notes that attempts to address those costs in a sustainable way will require consideration of how the US health system is designed and how the system balances the use of market mechanisms with the costs they sometimes entail.

Economic Incentives for Administrative Simplification

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JAMA. Published online October 20, 2021. doi:10.1001/jama.2021.18292

This Viewpoint explores the misaligned incentives impeding administrative spending reduction and suggests potential changes for administrative simplification.

October 18, 2021
Viewpoint

The Affordable Care Act Resurrected: Curtailing the Ranks of the Uninsured

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JAMA. Published online October 18, 2021. doi:10.1001/jama.2021.17531

This Viewpoint examines the coverage gap in health insurance in the US and its potential redress by enhancing federal outreach to the uninsured, rendering permanent the health insurance benefits of the American Rescue Plan Act, and establishing a federal health insurance program for low-income adults in states that did not expand their Medicaid programs.

October 15, 2021
JAMA Insights

Women's Health

Cancer-Related Cognitive Impairment in Patients With a History of Breast Cancer

Abstract Full Text
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JAMA. Published online October 15, 2021. doi:10.1001/jama.2021.13309

This JAMA Insights Clinical Update discusses cancer-related cognitive impairment, including risks, management recommendations, and cognitive and behavioral treatments.

October 14, 2021
Medical News & Perspectives

Quick Uptakes

COVID-19 Precautions Help Make Music That’s Beautiful and Safe

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JAMA. Published online October 14, 2021. doi:10.1001/jama.2021.17558

This Medical News article describes simple measures like masking instruments, social distancing, and curtailing performance length to improve safety for musicians and their audiences during live performances.

Trying to Block SARS-CoV-2 Transmission With Intranasal Vaccines

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JAMA. Published online October 14, 2021. doi:10.1001/jama.2021.18143

This Medical News feature discusses the ongoing research into intranasal COVID-19 vaccines.

October 13, 2021
Research Letter

Changes in COVID-19 Vaccine Intent From April/May to June/July 2021

Abstract Full Text
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JAMA. Published online October 13, 2021. doi:10.1001/jama.2021.18761

This study uses data from a nationally representative longitudinal study of adults in the US to examine individual-level change in vaccine intent and uptake between April and July 2021.

Viewpoint

Reducing Sodium Intake in the US: Healthier Lives, Healthier Future

Abstract Full Text
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JAMA. Published online October 13, 2021. doi:10.1001/jama.2021.18611

This Viewpoint summarizes new guidance from the US Food and Drug Administration (FDA) for industry to voluntarily adhere to sodium reduction targets, particularly in processed and prepared foods.

October 11, 2021
Original Investigation

Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19: The ACTIV-4B Randomized Clinical Trial

Abstract Full Text
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JAMA. Published online October 11, 2021. doi:10.1001/jama.2021.17272

This randomized clinical trial assesses whether aspirin, prophylactic-dose apixaban, or therapeutic-dose apixaban, compared with placebo, can safely reduce major adverse cardiopulmonary outcomes among symptomatic but clinically stable US outpatients with COVID-19.

Research Letter

Temporal Trends in Stroke Thrombolysis in the US by Race and Ethnicity, 2009-2018

Abstract Full Text
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JAMA. Published online October 11, 2021. doi:10.1001/jama.2021.12966

This study investigates the temporal trend in racial and ethnic differences in use of intravenous thrombolysis for stroke treatment between 2009 and 2018 in a representative sample of US adults.

Editorial

Antithrombotic Therapy for Outpatients With COVID-19: Implications for Clinical Practice and Future Research

Abstract Full Text
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JAMA. Published online October 11, 2021. doi:10.1001/jama.2021.17460
October 6, 2021
Research Letter

COVID-19 Incidence and Mortality in Federal and State Prisons Compared With the US Population, April 5, 2020, to April 3, 2021

Abstract Full Text
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JAMA. Published online October 6, 2021. doi:10.1001/jama.2021.17575

This study examines COVID-19 cases and deaths among US federal and state prisoners from April 5, 2020, to April 3, 2021, compared with cases and deaths in the overall US population.

Correction

Error in Discussion

Abstract Full Text
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JAMA. Published online October 6, 2021. doi:10.1001/jama.2021.18428

Incorrect Patient Data Reported

Abstract Full Text
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JAMA. Published online October 6, 2021. doi:10.1001/jama.2021.18721
October 4, 2021
Original Investigation

Caring for the Critically Ill Patient

Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial

Abstract Full Text
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JAMA. Published online October 4, 2021. doi:10.1001/jama.2021.18178

This study compares the effect of convalescent plasma vs no convalescent plasma on the outcome of organ support–free days in the hospital among critically ill adults with COVID-19 who had been randomized to the immunoglobulin domain in the ongoing REMAP-CAP trial.

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