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July 28, 2021
Medical News & Perspectives

Überantibodies From Recovered COVID-19 Patients Could Spur New Therapeutics and Vaccines

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JAMA. Published online July 28, 2021. doi:10.1001/jama.2021.12915

This Medical News article describes how ultrapotent antibodies discovered in patients who recovered from COVID-19 could be key players in new treatments and vaccines.

July 26, 2021
Viewpoint

Using Updated PubMed: New Features and Functions to Enhance Literature Searches

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JAMA. Published online July 26, 2021. doi:10.1001/jama.2021.12021

This Viewpoint describes how the updated functionality of PubMed could be useful to clinicians searching for answers to important clinical questions in real time.

July 23, 2021
Research Letter

Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses

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JAMA. Published online July 23, 2021. doi:10.1001/jama.2021.12339

This study examines the antibody responses to a third dose (100 μg) of the mRNA-1273 SARS-CoV-2 vaccine among kidney transplant recipients in France who had not responded to 2 doses of the vaccine.

Viewpoint

The Triple Aim for Payment Reform in Joint Replacement Surgery: Quality, Spending, and Disparity Reduction

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JAMA. Published online July 23, 2021. doi:10.1001/jama.2021.12070

This Viewpoint discusses the Comprehensive Care for Joint Replacement model created by the Centers for Medicare & Medicaid Services and how it and other payment reforms can help reduce disparities in joint replacements and other high-priority conditions nationally.

July 22, 2021
Viewpoint

Expanding Evidence for Clinical Care of Older Adults: Beyond Clinical Trial Traditions and Finding New Approaches

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JAMA. Published online July 22, 2021. doi:10.1001/jama.2021.12134

This Viewpoint highlights why complementary approaches, which often have received less attention, are necessary to enhance the evidence needed to inform care for older adults.

July 21, 2021
Research Letter

Age-Dependent Neutralization of SARS-CoV-2 and P.1 Variant by Vaccine Immune Serum Samples

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JAMA. Published online July 21, 2021. doi:10.1001/jama.2021.11656

This study examines the relationship between age and neutralizing antibody titers against the SARS-CoV-2 USA-WA1/2020 strain and the P.1 variant after 2 doses of the BNT162b2 vaccine.

Medical News & Perspectives

Recently Approved Alzheimer Drug Raises Questions That Might Never Be Answered

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JAMA. Published online July 21, 2021. doi:10.1001/jama.2021.11558

This Medical News feature examines the debate over which patients with Alzheimer disease, if any, might benefit from the newly approved drug aducanumab.

July 19, 2021
Research Letter

Trends in Mortality From COVID-19 and Other Leading Causes of Death Among Latino vs White Individuals in Los Angeles County, 2011-2020

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JAMA. Published online July 19, 2021. doi:10.1001/jama.2021.11945

This study compares age-adjusted mortality rates before and during the COVID-19 pandemic among Latino and White individuals living in Los Angeles County.

Viewpoint

Will CMS Find Aducanumab Reasonable and Necessary for Alzheimer Disease After FDA Approval?

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JAMA. Published online July 19, 2021. doi:10.1001/jama.2021.11768

This Viewpoint discusses the recently approved drug aducanumab as a treatment for Alzheimer disease and whether it might be covered under Medicare, a decision made by CMS administrators.

July 16, 2021
Original Investigation

Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial

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JAMA. Published online July 16, 2021. doi:10.1001/jama.2021.11517

This randomized trial assesses the effect of a single dose of azithromycin vs placebo on absence of COVID-19 symptoms at posttreatment day 14 among outpatients with SARS-CoV-2 infection.

July 15, 2021
Research Letter

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents

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JAMA. Published online July 15, 2021. doi:10.1001/jama.2021.11880

This cohort study reports the prevalence of long-term symptoms in children and adolescents who had recovered from acute SARS-CoV-2 infection.

Viewpoint

Potential Benefits of Expanded COVID-19 Surveillance in the US

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JAMA. Published online July 15, 2021. doi:10.1001/jama.2021.11211

This Viewpoint proposes several important areas of surveillance expansion by US public health agencies and other institutions for COVID-19 testing, vaccination, infection, and mortality rates.

July 14, 2021
Medical News & Perspectives

Quick Uptakes

Study Suggests Lasting Immunity After COVID-19, With a Big Boost From Vaccination

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JAMA. Published online July 14, 2021. doi:10.1001/jama.2021.11717

This Medical News article discusses the duration of immunity after SARS-CoV-2 infection.

July 12, 2021
Original Investigation

Association Between BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women

Abstract Full Text
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JAMA. Published online July 12, 2021. doi:10.1001/jama.2021.11035

This cohort study explores the risk of SARS-CoV-2 infection in pregnant women vaccinated with BNT162b2 vaccine (Pfizer-BioNTech) vs those unvaccinated.

July 6, 2021
Original Investigation

Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis

Abstract Full Text
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JAMA. Published online July 6, 2021. doi:10.1001/jama.2021.11330

This prospective meta-analysis estimates the association between administration of IL-6 antagonists compared with usual care or placebo and 28-day all-cause mortality and other outcomes.

Editorial

IL-6 Receptor Antagonist Therapy for Patients Hospitalized for COVID-19: Who, When, and How?

Abstract Full Text
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JAMA. Published online July 6, 2021. doi:10.1001/jama.2021.11121
July 2, 2021
Research Letter

Lottery-Based Incentive in Ohio and COVID-19 Vaccination Rates

Abstract Full Text
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JAMA. Published online July 2, 2021. doi:10.1001/jama.2021.11048

This study assesses changes in COVID-19 vaccination rates before and after the Ohio vaccine lottery announcement compared with national rates to control for the expansion of vaccine indications to adolescents.

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