This case-control study uses data from the Centers for Disease Control and Prevention Increasing Community Access to Testing platform to estimate the association between receipt of 3 doses of Pfizer-BioNTech BNT162b2 or Moderna mRNA-1273 vaccine, compared with 2 doses or unvaccinated, and symptomatic SARS-CoV-2 infection, stratified by Omicron and Delta variant.
This Viewpoint proposes using large longitudinal databases of patient information that describe clinical trajectories and outcomes to preemptively quantify the risk of overdiagnosis posed by new digital screening technologies.
This Viewpoint proposes expanding the quadruple aim (improving population health, enhancing the care experience, reducing costs, and addressing clinician burnout) to the quintuple aim, adding a fifth aim of advancing health equity.
This Viewpoint argues that equitable health care is not possible without the delivery of high-quality care and vice versa.
This Viewpoint examines the recent US Supreme Court rulings on government mandates for COVID-19 vaccination and how these decisions might affect the ongoing pandemic response as well as the future of public health.
This Medical News article discusses the Supreme Court’s recent decision to allow federally mandated COVID-19 vaccinations for health care workers but not the broader US workforce.
This study examines breakthrough SARS-CoV-2 infections, hospitalizations, and mortality in March-August 2021, when the Delta variant predominated, among a general US cohort vaccinated with mRNA-1273 or BNT162b2.
This Viewpoint discusses the definitions of medical devices and low-risk general wellness products and examines the difficulties the difference between these types of products pose for regulation, consumer understanding, physician use and interpretation, privacy, reimbursement, and equity.
This Medical News article discusses the first ever malaria vaccine, which begins rolling out this year in sub-Saharan Africa.
This Medical News article is based on an interview with 3 members of the former Biden-Harris Transition COVID-19 Advisory Board.
This randomized trial assesses the effect of a single dose of subcutaneous casirivimab and imdevimab antibody combination vs placebo on 28-day progression to symptomatic COVID-19 among asymptomatic SARS-CoV-2 reverse transcriptase–quantitative polymerase chain reaction–positive individuals living with an infected household contact.
This Viewpoint discusses the implications from data on value-based payments, policy design regarding population- and episode-based payments, and the benefits of coordinated payment models that may contribute toward reaching the Centers for Medicare & Medicaid Services’ strategy, announced in November 2021, for achieving near-universal participation in value-based payment models by 2030.
This Viewpoint provides a summary of currently available therapeutics for nonhospitalized patients with COVID-19 in the setting of the Omicron variant including principles for equitable allocation.
This study examines insurer coverage of ivermectin prescriptions for COVID-19 in the US.
This Viewpoint discusses the increased long-term risks for cardiovascular disease among individuals who have had adverse pregnancy outcomes and describes mitigation strategies for physicians to use over the life span of these patients.
This Medical News feature examines the challenges that hospitals face as they prepare for a spike in severe cases of COVID-19 and other respiratory illnesses that require supplemental oxygen.
This Medical News article examines the growing business of unlicensed and unproven stem cell treatments.
This Medical News article on COVID-19 vaccines is adapted from a JAMA interview with the CDC’s Amanda Cohn, MD.
This cohort study estimates the association of a BNT162b2 (Pfizer-BioNTech) vaccine booster dose with SARS-CoV-2 infections among health care workers in Israel previously vaccinated with a 2-dose series of BNT162b2.
This study examines the incidence of false-positive results in a sample of rapid antigen tests used to serially screen asymptomatic workers throughout Canada.
This Viewpoint focuses on an emerging intervention, serious illness communication, and describes its components, presents evidence supporting the approach, and discusses areas for further research.
This Viewpoint discusses addressing the problems in the health benefits market, which contribute to wage stagnation and rising economic inequality.
This Viewpoint outlines approaches to successfully make clinical diagnoses, including coaching medical students in critical thinking and decision-making, promoting interdisciplinary teamwork, and mitigating judgment and decision-making biases.
Timely topics discussed at the American Heart Association’s Scientific Sessions in November 2021 included using apolipoprotein B to predict the risk of future myocardial infarction.