[Skip to Content]
[Skip to Content Landing]
Comment & Response
March 2017

Atrial Fibrillation and Cancer—Validation in the Real World

Author Affiliations
  • 1Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio
  • 2School of Medicine, Case Western Reserve University, Cleveland, Ohio
  • 3Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio
JAMA Cardiol. 2017;2(3):343-344. doi:10.1001/jamacardio.2016.3981

To the Editor We read with interest the article by Conen et al1 published in the April issue of JAMA Cardiology. In an analysis of the Women’s Health Study, the authors found an association between incident atrial fibrillation (AF) and cancer. While the study cohort was large, the incidences of AF and cancer were low, placing the findings at risk of a type II error. In addition, this association was not generalizable to men. Therefore, we sought to validate these findings in a larger real-world cohort among both sexes.

×