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Comment & Response
July 2017

Microangiopathy, Arterial Stiffness, and Risk Stratification in Patients With Type 2 Diabetes—Reply

Author Affiliations
  • 1TIMI Study Group, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
JAMA Cardiol. 2017;2(7):821. doi:10.1001/jamacardio.2017.0164

In Reply We thank Antonopoulos et al for their letter and in particular for highlighting the importance of microvascular complications in patients with diabetes. Risk stratification remains challenging in patients with type 2 diabetes because of the complex interplay between underlying pathologic processes. Microvascular disease (eg, nephropathy, retinopathy, and neuropathy) is both a complication of diabetes and a well-established risk factor for future complications, including renal failure, heart failure, and death.1,2

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