To the Editor Coronary computed tomography angiography (cCTA)–based fractional flow reserve (FFR-CT) is an evolving technology of disruptive potential to noninvasively determine the hemodynamic significance of a coronary artery stenosis. The systematic review by Cook et al1 provides an excellent overview on the status of this innovative method. In their Methods section, the authors mention the FFR-CT algorithm approved by the US Food and Drug Administration in late 2014.1 However, technology and evidence in this field are rapidly evolving, which adds new facets to their discussion.
Baumann S, Renker M, Schoepf UJ. Coronary Computed Tomography–Based Fractional Flow Reserve: A Rapidly Developing Field. JAMA Cardiol. 2018;3(1):87. doi:10.1001/jamacardio.2017.4249
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