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Invited Commentary
January 30, 2019

Extreme Physical Activity and Coronary Artery Calcification—Running Heavily and Safely With “Hearts of Stone”

Author Affiliations
  • 1Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School, University of Queensland School of Medicine, New Orleans, Louisiana
  • 2Cardiac Exercise Research Group, Department of Circulation and Medical Imaging, Faculty of Medicine and Health Science, Norwegian University of Science and Technology, Trondheim, Norway
  • 3John Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Baltimore, Maryland
JAMA Cardiol. 2019;4(2):182-183. doi:10.1001/jamacardio.2018.4647

Ozemek et al1 and Lavie et al2 have emphasized that sedentary behavior, physical inactivity, and low levels of physical activity resulting in poor cardiorespiratory fitness are among the greatest threats to health in the 21st century. For this reason, a recent health promotion series3 and recent update on physical activity guidelines4 have emphasized limiting sedentary behavior and physical inactivity and promoting appropriate physical activity and exercise to improve cardiorespiratory fitness and reduce major cardiovascular disease (CVD) and all-cause morbidity and mortality worldwide.

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