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Comment & Response
May 15, 2019

Risks of High Coronary Artery Calcium

Author Affiliations
  • 1Los Angeles Biomedical Research Institute at Harbor–UCLA Medical Center, Torrance, California
JAMA Cardiol. 2019;4(7):712. doi:10.1001/jamacardio.2019.1400

To the Editor We read with great interest the article by DeFina et al1 in a recent issue of JAMA Cardiology. The authors are to be commended on their unquestionably important observations. In this article, DeFina et al1 evaluated the prevalence of coronary artery calcium (CAC) among men with high levels of physical activity and their subsequent mortality risk. The authors concluded that high levels of physical activity (>3000 metabolic equivalent of task [MET]–minutes/week) are associated with prevalent CAC but not associated with increased all-cause or cardiovascular disease mortality after a decade of follow-up compared with lower levels of physical activity.

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