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Invited Commentary
January 2, 2020

Comparing Percutaneous Coronary Intervention Access Sites for ST-Elevation Myocardial Infarction—Are Radial and Femoral Access Equally Safe?

Author Affiliations
  • 1Department of Medicine–Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
JAMA Cardiol. Published online January 2, 2020. doi:10.1001/jamacardio.2019.5356

In this issue of JAMA Cardiology, Le May et al1 report on the Safety and Efficacy of Femoral Access vs Radial Access in ST-Elevation Myocardial Infarction (SAFARI-STEMI) study, a randomized clinical trial of radial vs femoral access for percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). This multicenter Canadian study enrolled 2292 patients and found a 30-day mortality rate of 1.5% in patients assigned to radial access compared with 1.3% in patients assigned to femoral access (relative risk, 1.15; 95% CI, 0.58-2.30; P = .69). Secondary outcome analyses revealed no statistically significant differences in bleeding, reinfarction, stent thrombosis, or stroke.

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