Tobacco is the leading preventable cause of mortality in the Unites States, but, regrettably, society has paid less attention to tobacco compared with other causes. Prior to coronavirus disease 2019 (COVID-19) coverage, over the last few years, the media has focused awareness predominantly on suicide, gun violence, and opioid-related mortality. While these issues elicit justifiable concern, it is now time to focus more on tobacco. Cigarette smoking is the main source of tobacco’s morbidity and mortality, and its mortality is greater than that caused by activities receiving the greatest attention. In 2017, there were 47 000 deaths by suicide, 14 500 deaths by gun violence, and 70 000 opioid-related deaths.1 In contrast, tobacco accounted for nearly 500 000 deaths with a total economic cost of more than $300 billion annually and more than $156 billion in lost productivity.2